Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Sorin, Ravenous Neonate

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
+2: Create a Food token.
−1: Sorin, Ravenous Neonate deals damage equal to the amount of life you gained this turn to any target.
−6: Gain control of target creature. It becomes a Vampire in addition to its other types. Put a lifelink counter on it if you control a white permanent other than that creature or Sorin.

Sorin of House Markov

Lifelink
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
At the beginning of your second main phase, if you gained 3 or more life this turn, exile Sorin of House Markov, then return him to the battlefield transformed under his owner's control.

Sorin of House Markov // Sorin, Ravenous Neonate

Disenchant

Invoke the Divine

Destroy target artifact or enchantment. You gain 4 life.

Suture Priest

Whenever another creature you control enters, you may gain 1 life.
Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Promise of Tomorrow

Whenever a creature you control dies, exile it.
At the beginning of each end step, if you control no creatures, sacrifice Promise of Tomorrow and return all cards exiled with it to the battlefield under your control.

Beloved Princess

Lifelink
Beloved Princess can't be blocked by creatures with power 3 or greater.

Silverquill Command

Choose two —
• Target creature gets +3/+3 and gains flying until end of turn.
• Return target creature card with mana value 2 or less from your graveyard to the battlefield.
• Target player draws a card and loses 1 life.
• Target opponent sacrifices a creature.

Cruel Celebrant

Whenever Cruel Celebrant or another creature or planeswalker you control dies, each opponent loses 1 life and you gain 1 life.

Orzhov Signet

Orzhov Basilica

Orzhov Basilica enters tapped.
When Orzhov Basilica enters, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Gift of Orzhova

Enchant creature
Enchanted creature gets +1/+1 and has flying and lifelink.

Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)

Plains

Swamp

Lunar Convocation

At the beginning of your end step, if you gained life this turn, each opponent loses 1 life.
At the beginning of your end step, if you gained and lost life this turn, create a 1/1 black Bat creature token with flying.
{1}{B}, Pay 2 life: Draw a card.

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Kambal, Profiteering Mayor

Whenever one or more tokens your opponents control enter, for each of them, create a tapped token that's a copy of it. This ability triggers only once each turn.
Whenever one or more tokens you control enter, each opponent loses 1 life and you gain 1 life.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Murder

Infernal Grasp

Destroy target creature. You lose 2 life.

Single Combat

Each player chooses a creature or planeswalker they control, then sacrifices the rest. Players can't cast creature or planeswalker spells until the end of your next turn.

Tithe Drinker

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Black Sun's Twilight

Up to one target creature gets -X/-X until end of turn. If X is 5 or more, return a creature card with mana value X or less from your graveyard to the battlefield tapped.

White Sun's Twilight

You gain X life. Create X 1/1 colorless Phyrexian Mite artifact creature tokens with toxic 1 and "This creature can't block." If X is 5 or more, destroy all other creatures. (Players dealt combat damage by a creature with toxic 1 also get a poison counter.)

Tomik, Wielder of Law

Affinity for planeswalkers (This spell costs {1} less to cast for each planeswalker you control.)
Flying, vigilance
Whenever an opponent attacks with creatures, if two or more of those creatures are attacking you and/or planeswalkers you control, that opponent loses 3 life and you draw a card.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Witch's Oven

{T}, Sacrifice a creature: Create a Food token. If the sacrificed creature's toughness was 4 or greater, create two Food tokens instead. (They're artifacts with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")

Fell Stinger

Deathtouch
Exploit (When this creature enters, you may sacrifice a creature.)
When Fell Stinger exploits a creature, target player draws two cards and loses 2 life.

Deathgreeter

Whenever another creature dies, you may gain 1 life.

Dash Hopes

When you cast this spell, any player may pay 5 life. If a player does, counter Dash Hopes.
Counter target spell.

Wishclaw Talisman

Wishclaw Talisman enters with three wish counters on it.
{1}, {T}, Remove a wish counter from Wishclaw Talisman: Search your library for a card, put it into your hand, then shuffle. An opponent gains control of Wishclaw Talisman. Activate only during your turn.

Scheming Symmetry

Choose two target players. Each of them searches their library for a card, then shuffles and puts that card on top.

Kor Cartographer

When Kor Cartographer enters, you may search your library for a Plains card, put it onto the battlefield tapped, then shuffle.

Divine Gambit

Exile target artifact, creature, or enchantment an opponent controls. That player may put a permanent card from their hand onto the battlefield.

Faith's Fetters

Enchant permanent
When Faith's Fetters enters, you gain 4 life.
Enchanted permanent can't attack or block, and its activated abilities can't be activated unless they're mana abilities.

Angelic Gift

Enchant creature
When Angelic Gift enters, draw a card.
Enchanted creature has flying.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Sol Ring

Liesa, Shroud of Dusk

Rather than pay {2} for each previous time you've cast this spell from the command zone this game, pay 2 life that many times.
Flying, lifelink
Whenever a player casts a spell, they lose 2 life.

Shadows of the Past

Whenever a creature dies, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{4}{B}: Each opponent loses 2 life and you gain 2 life. Activate only if there are four or more creature cards in your graveyard.

Shadows' Lair

(Transforms from Grasping Shadows.)
{T}: Add {B}.
{B}, {T}, Remove a dread counter from Shadows' Lair: You draw a card and you lose 1 life.

Grasping Shadows

Whenever a creature you control attacks alone, it gains deathtouch and lifelink until end of turn. Put a dread counter on Grasping Shadows. Then if there are three or more dread counters on it, transform it.

Grasping Shadows // Shadows' Lair

Markov Purifier

Lifelink
At the beginning of your end step, if you gained life this turn, you may pay {2}. If you do, draw a card.

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Fracture

Destroy target artifact, enchantment, or planeswalker.

Abstruse Appropriation

Devoid (This card has no color.)
Exile target nonland permanent. You may cast that card for as long as it remains exiled, and you may spend colorless mana as though it were mana of any color to cast that spell.

Crypt Incursion

Exile all creature cards from target player's graveyard. You gain 3 life for each card exiled this way.

Village Rites

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

Night's Whisper

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Filigree Familiar

When Filigree Familiar enters, you gain 2 life.
When Filigree Familiar dies, draw a card.

Radiant Fountain

When Radiant Fountain enters, you gain 2 life.
{T}: Add {C}.

Pristine Talisman

Midnight Reaper

Whenever a nontoken creature you control dies, Midnight Reaper deals 1 damage to you and you draw a card.

Morbid Opportunist

Whenever one or more other creatures die, draw a card. This ability triggers only once each turn.

Sinister Monolith

At the beginning of combat on your turn, each opponent loses 1 life and you gain 1 life.
{T}, Pay 2 life, Sacrifice Sinister Monolith: Draw two cards. Activate only as a sorcery.