Skymarch Bloodletter

Flying
When this creature enters, target opponent loses 1 life and you gain 1 life.

Ghastly Gloomhunter

Kicker {3}{B} (You may pay an additional {3}{B} as you cast this spell.)
Flying, lifelink
If this creature was kicked, it enters with two +1/+1 counters on it.

Unexpected Fangs

Put a +1/+1 counter and a lifelink counter on target creature.

Nocturnal Hunger

Gift a Food (You may promise an opponent a gift as you cast this spell. If you do, they create a Food token before its other effects. It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")
Destroy target creature. If the gift wasn't promised, you lose 2 life.

Don't Have

Maestros Theater

When this land enters, sacrifice it. When you do, search your library for a basic Island, Swamp, or Mountain card, put it onto the battlefield tapped, then shuffle and you gain 1 life.

Spirit of Malevolence

When this creature dies, each opponent loses 1 life and you gain 1 life.

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Pendulum of Patterns

When this artifact enters, you gain 3 life.
{5}, {T}, Sacrifice this artifact: Draw a card.

Desperate Bloodseeker

Lifelink
When this creature enters, target player mills two cards. (They put the top two cards of their library into their graveyard.)

Merciless Harlequin

Freerunning {1}{B} (You may cast this spell for its freerunning cost if you dealt combat damage to a player this turn with an Assassin or commander.)
When this creature enters, you draw a card and you lose 1 life.

Kami of Terrible Secrets

When this creature enters, if you control an artifact and an enchantment, you draw a card and you gain 1 life.

Grotesque Mutation

Target creature gets +3/+1 and gains lifelink until end of turn. (Damage dealt by the creature also causes its controller to gain that much life.)

Getting

Witch's Cauldron

{1}{B}, {T}, Sacrifice a creature: You gain 1 life and draw a card.

Serrated Scorpion

When this creature dies, it deals 2 damage to each opponent and you gain 2 life.

Crushing Disappointment

Each player loses 2 life. You draw two cards.

Breathe Your Last

Destroy target creature or planeswalker. You gain 1 life for each of its colors.

Lampad of Death's Vigil

{1}, Sacrifice a creature: Each opponent loses 1 life and you gain 1 life.

Have

Swamp

Herald of Hadar

Circle of Death — {5}{B}: Roll a d20.
1—9 | Each opponent loses 2 life.
10—19 | Each opponent loses 2 life and you gain 2 life.
20 | Each opponent loses 2 life and you gain 2 life. Create two Treasure tokens. (They're artifacts with "{T}, Sacrifice this token: Add one mana of any color.")

Basilica Screecher

Flying
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Terramorphic Expanse

{T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Evolving Wilds

Toxin Analysis

Target creature gains deathtouch and lifelink until end of turn. Investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this token: Draw a card.")

Brotherhood Patriarch

When this creature dies, each opponent loses 2 life and you gain 2 life.

Sign in Blood

Target player draws two cards and loses 2 life.

Lembas

When this artifact enters, scry 1, then draw a card.
{2}, {T}, Sacrifice this artifact: You gain 3 life.
When this artifact is put into a graveyard from the battlefield, its owner shuffles it into their library.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Nezumi Road Captain

Menace
Vehicles you control have menace. (They can't be blocked except by two or more creatures.)

Okiba Reckoner Raid

(As this Saga enters and after your draw step, add a lore counter.)
I, II — Each opponent loses 1 life and you gain 1 life.
III — Exile this Saga, then return it to the battlefield transformed under your control.

Okiba Reckoner Raid // Nezumi Road Captain

Reckoner's Bargain

As an additional cost to cast this spell, sacrifice an artifact or creature.
You gain life equal to the sacrificed permanent's mana value. Draw two cards.

Creeping Bloodsucker

At the beginning of your upkeep, this creature deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Candy Trail

When this artifact enters, scry 2.
{2}, {T}, Sacrifice this artifact: You gain 3 life and draw a card.

Rooftop Assassin

Flash
Flying, lifelink
When this creature enters, destroy target creature an opponent controls that was dealt damage this turn.

Vampire's Kiss

Target player loses 2 life and you gain 2 life. Create two Blood tokens. (They're artifacts with "{1}, {T}, Discard a card, Sacrifice this token: Draw a card.")

Demon's Due

Scry 2, then draw two cards. You lose 2 life.

Starlit Soothsayer

Flying
At the beginning of your end step, if you gained or lost life this turn, surveil 1. (Look at the top card of your library. You may put it into your graveyard.)

Drossclaw

Living weapon (When this Equipment enters, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +1/+1.
Whenever equipped creature attacks, each opponent loses 1 life.
Equip {2}

Nocturnal Feeder

Flying
When this creature dies, each opponent loses 2 life and you gain 2 life.

Filigree Familiar

When this creature enters, you gain 2 life.
When this creature dies, draw a card.

Alley Assailant

This creature enters tapped.
Disguise {4}{B}{B} (You may cast this card face down for {3} as a 2/2 creature with ward {2}. Turn it face up any time for its disguise cost.)
When this creature is turned face up, target opponent loses 3 life and you gain 3 life.

Courier Bat

Flying
When this creature enters, if you gained life this turn, return up to one target creature card from your graveyard to your hand.

Urborg Syphon-Mage

{2}{B}, {T}, Discard a card: Each other player loses 2 life. You gain life equal to the life lost this way.

Etched Host Doombringer

When this creature enters, choose one —
• Target opponent loses 2 life and you gain 2 life.
• Choose target battle. If an opponent protects it, remove three defense counters from it. Otherwise, put three defense counters on it.

Parasitic Impetus

Enchant creature
Enchanted creature gets +2/+2 and is goaded. (It attacks each combat if able and attacks a player other than you if able.)
Whenever enchanted creature attacks, its controller loses 2 life and you gain 2 life.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Marauding Blight-Priest

Lich's Caress

Destroy target creature. You gain 3 life.

Basilica Stalker

Flying
Whenever this creature deals combat damage to a player, you gain 1 life and surveil 1. (Look at the top card of your library. You may put it into your graveyard.)
Disguise {4}{B} (You may cast this card face down for {3} as a 2/2 creature with ward {2}. Turn it face up any time for its disguise cost.)

Glidedive Duo

Flying
When this creature enters, each opponent loses 2 life and you gain 2 life.

Diresight

Surveil 2, then draw two cards. You lose 2 life. (To surveil 2, look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Vampire Spawn

When this creature enters, each opponent loses 2 life and you gain 2 life.

Peace Strider

When this creature enters, you gain 3 life.

Riveteers Overlook

When this land enters, sacrifice it. When you do, search your library for a basic Swamp, Mountain, or Forest card, put it onto the battlefield tapped, then shuffle and you gain 1 life.

Dreamdrinker Vampire

Lifelink
{1}{B}: Adapt 1. (If this creature has no +1/+1 counters on it, put a +1/+1 counter on it.)
Whenever one or more +1/+1 counters are put on this creature, it gains menace until end of turn.

Extinguish the Light

Destroy target creature or planeswalker. If its mana value was 3 or less, you gain 3 life.

Bloodhunter Bat

Flying
When this creature enters, target player loses 2 life and you gain 2 life.

Etched Familiar

Blood Pact

Starscape Cleric

Offspring {2}{B} (You may pay an additional {2}{B} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Flying
This creature can't block.
Whenever you gain life, each opponent loses 1 life.

Pristine Talisman

Consuming Sepulcher

At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Tithing Blade

When this artifact enters, each opponent sacrifices a creature of their choice.
Craft with creature {4}{B} ({4}{B}, Exile this artifact, Exile a creature you control or a creature card from your graveyard: Return this card transformed under its owner's control. Craft only as a sorcery.)

Tithing Blade // Consuming Sepulcher

Tendrils of Corruption

Tendrils of Corruption deals X damage to target creature and you gain X life, where X is the number of Swamps you control.

Raven of Fell Omens

Flying
Whenever you commit a crime, each opponent loses 1 life and you gain 1 life. This ability triggers only once each turn. (Targeting opponents, anything they control, and/or cards in their graveyards is a crime.)

Radiant Fountain

When this land enters, you gain 2 life.
{T}: Add {C}.

Scales of Shale

Affinity for Lizards (This spell costs {1} less to cast for each Lizard you control.)
Target creature gets +2/+0 and gains lifelink and indestructible until end of turn.

Agate-Blade Assassin

Whenever this creature attacks, defending player loses 1 life and you gain 1 life.

Blight Keeper

Flying
{7}{B}, {T}, Sacrifice this creature: Target opponent loses 4 life and you gain 4 life.

Vermin Gorger

{T}, Sacrifice another creature: Each opponent loses 2 life and you gain 2 life.

Campfire

{1}, {T}: You gain 2 life.
{2}, {T}, Exile this artifact: Put all commanders you own from the command zone and from your graveyard into your hand. Then shuffle your graveyard into your library.

Sanguine Indulgence

This spell costs {3} less to cast if you've gained 3 or more life this turn.
Return up to two target creature cards from your graveyard to your hand.

Night's Whisper

Vampire Sovereign

Flying
When this creature enters, target opponent loses 3 life and you gain 3 life.

Leech Fanatic

During your turn, this creature has lifelink.

Specter of the Fens

Flying
{5}{B}: Target opponent loses 2 life and you gain 2 life.

Sweettooth Witch

When this creature enters, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")
{2}, Sacrifice a Food: Target player loses 2 life.

Moment of Defiance

Target creature gets +2/+1 and gains lifelink until end of turn.
Draw a card.

Sovereign's Bite

Target player loses 3 life and you gain 3 life.

Ill-Gotten Inheritance

At the beginning of your upkeep, this enchantment deals 1 damage to each opponent and you gain 1 life.
{5}{B}, Sacrifice this enchantment: It deals 4 damage to target opponent and you gain 4 life.

Obscura Storefront

When this land enters, sacrifice it. When you do, search your library for a basic Plains, Island, or Swamp card, put it onto the battlefield tapped, then shuffle and you gain 1 life.

Vampire Neonate

{2}, {T}: Each opponent loses 1 life and you gain 1 life.

Kami of Jealous Thirst

Deathtouch
{4}{B}: Each opponent loses 2 life and you gain 2 life. This ability costs {4}{B} less to activate if you've drawn three or more cards this turn. Activate only once each turn.

Severed Strands

As an additional cost to cast this spell, sacrifice a creature.
You gain life equal to the sacrificed creature's toughness. Destroy target creature an opponent controls.

Arrogant Outlaw

When this creature enters, if an opponent lost life this turn, each opponent loses 2 life and you gain 2 life.

Orcish Medicine

Target creature gains your choice of lifelink or indestructible until end of turn.
Amass Orcs 1. (Put a +1/+1 counter on an Army you control. It's also an Orc. If you don't control an Army, create a 0/0 black Orc Army creature token first.)