Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

The One Ring

Indestructible
When The One Ring enters, if you cast it, you gain protection from everything until your next turn.
At the beginning of your upkeep, you lose 1 life for each burden counter on The One Ring.
{T}: Put a burden counter on The One Ring, then draw a card for each burden counter on The One Ring.

Polluted Delta

{T}, Pay 1 life, Sacrifice this land: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Mortify

Guard Gomazoa

Defender, flying
Prevent all combat damage that would be dealt to this creature.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Mystic Gate

{T}: Add {C}.
{W/U}, {T}: Add {W}{W}, {W}{U}, or {U}{U}.

Cleric Class

(Gain the next level as a sorcery to add its ability.)
If you would gain life, you gain that much life plus 1 instead.
{3}{W}: Level 2
Whenever you gain life, put a +1/+1 counter on target creature you control.
{4}{W}: Level 3
When this Class becomes level 3, return target creature card from your graveyard to the battlefield. You gain life equal to that creature's toughness.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Maeve, Insidious Singer

{2}{U}: Goad target creature. Whenever that creature attacks one of your opponents this turn, you draw a card. (A goaded creature attacks each combat if able and attacks a player other than you if able, until your next turn.)

Angel of Vitality

Flying
If you would gain life, you gain that much life plus 1 instead.
This creature gets +2/+2 as long as you have 25 or more life.

Sea of Clouds

This land enters tapped unless you have two or more opponents.
{T}: Add {W} or {U}.

Nyx-Fleece Ram

At the beginning of your upkeep, you gain 1 life.

Liliana's Contract

When this enchantment enters, you draw four cards and you lose 4 life.
At the beginning of your upkeep, if you control four or more Demons with different names, you win the game.

Shattered Sanctum

This land enters tapped unless you control two or more other lands.
{T}: Add {W} or {B}.

Fetid Heath

{T}: Add {C}.
{W/B}, {T}: Add {W}{W}, {W}{B}, or {B}{B}.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

Hallowed Fountain

({T}: Add {W} or {U}.)
As this land enters, you may pay 2 life. If you don't, it enters tapped.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Fog Bank

Defender (This creature can't attack.)
Flying
Prevent all combat damage that would be dealt to and dealt by this creature.

Cathedral Membrane

({W/P} can be paid with either {W} or 2 life.)
Defender
When this creature dies during combat, it deals 6 damage to each creature it blocked this combat.

Dawn

Aftermath (Cast this spell only from your graveyard. Then exile it.)
Return all creature cards with power 2 or less from your graveyard to your hand.

Dusk

Destroy all creatures with power 3 or greater.

Dusk // Dawn

Archivist of Oghma

Flash
Whenever an opponent searches their library, you gain 1 life and draw a card.

Triskaidekaphobia

At the beginning of your upkeep, choose one —
• Each player with exactly 13 life loses the game, then each player gains 1 life.
• Each player with exactly 13 life loses the game, then each player loses 1 life.

Desolate Mire

Deserted Beach

This land enters tapped unless you control two or more other lands.
{T}: Add {W} or {U}.

Wall of Omens

Defender
When this creature enters, draw a card.

Sigarda's Splendor

As this enchantment enters, note your life total.
At the beginning of your upkeep, draw a card if your life total is greater than or equal to the last noted life total for this enchantment. Then note your life total.
Whenever you cast a white spell, you gain 1 life.

Speaker of the Heavens

Vigilance, lifelink (Attacking doesn't cause this creature to tap. Damage dealt by this creature also causes you to gain that much life.)
{T}: Create a 4/4 white Angel creature token with flying. Activate only if you have at least 7 life more than your starting life total and only as a sorcery.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Azorius Signet

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Marsh Flats

{T}, Pay 1 life, Sacrifice this land: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. This land deals 1 damage to you.

The Battle of Bywater

Destroy all creatures with power 3 or greater. Then create a Food token for each creature you control. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")

Boon Reflection

If you would gain life, you gain twice that much life instead.

Oloro, Ageless Ascetic

At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro is in the command zone, you gain 2 life.

Orzhov Signet

Nimbus Maze

{T}: Add {C}.
{T}: Add {W}. Activate only if you control an Island.
{T}: Add {U}. Activate only if you control a Plains.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Mana Confluence

{T}, Pay 1 life: Add one mana of any color.

Wall of Reverence

Defender, flying
At the beginning of your end step, you may gain life equal to the power of target creature you control.

Heliod, Sun-Crowned

Indestructible
As long as your devotion to white is less than five, Heliod isn't a creature.
Whenever you gain life, put a +1/+1 counter on target creature or enchantment you control.
{1}{W}: Another target creature gains lifelink until end of turn.

Perimeter Captain

Defender
Whenever a creature you control with defender blocks, you may gain 2 life.

Godless Shrine

({T}: Add {W} or {B}.)
As this land enters, you may pay 2 life. If you don't, it enters tapped.

Ancient Ziggurat

{T}: Add one mana of any color. Spend this mana only to cast a creature spell.

Skycloud Expanse

Felidar Sovereign

Vigilance (Attacking doesn't cause this creature to tap.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Silent Clearing

{T}, Pay 1 life: Add {W} or {B}.
{1}, {T}, Sacrifice this land: Draw a card.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Eye of Vecna

When Eye of Vecna enters, you draw a card and you lose 2 life.
At the beginning of your upkeep, you may pay {2}. If you do, you draw a card and you lose 2 life.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Adarkar Wastes

{T}: Add {C}.
{T}: Add {W} or {U}. This land deals 1 damage to you.

Wall of Denial

Defender, flying
Shroud (This creature can't be the target of spells or abilities.)

Isolated Chapel

This land enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Wall of Essence

Defender (This creature can't attack.)
Whenever this creature is dealt combat damage, you gain that much life.

Plains

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Wall of Runes

Defender (This creature can't attack.)
When this creature enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Pristine Talisman

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, this creature gets +5/+5 and has flying.

Fortified Rampart

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Voice of the Blessed

Whenever you gain life, put a +1/+1 counter on this creature.
As long as this creature has four or more +1/+1 counters on it, it has flying and vigilance.
As long as this creature has ten or more +1/+1 counters on it, it has indestructible.

Flooded Strand

{T}, Pay 1 life, Sacrifice this land: Search your library for a Plains or Island card, put it onto the battlefield, then shuffle.

City of Brass

Whenever this land becomes tapped, it deals 1 damage to you.
{T}: Add one mana of any color.

Vault of Champions

This land enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Propaganda

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with this creature's toughness.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: This artifact deals 50 damage to any target.

Riptide Turtle

Sinner's Judgment

Enchant player
At the beginning of your upkeep, put a judgment counter on this Aura. Then if there are three or more judgment counters on it, enchanted player loses the game.
If Sinner's Judgment would be put into a graveyard from anywhere, exile it instead.

Faithbound Judge

Defender, flying, vigilance
At the beginning of your upkeep, if this creature has two or fewer judgment counters on it, put a judgment counter on it.
As long as this creature has three or more judgment counters on it, it can attack as though it didn't have defender.
Disturb {5}{W}{W}

Faithbound Judge // Sinner's Judgment

Wall of Hope

Defender (This creature can't attack.)
Whenever this creature is dealt damage, you gain that much life.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Command Tower

Wall of Air

Defender, flying (This creature can't attack, and it can block creatures with flying.)

Three Tree City

As Three Tree City enters, choose a creature type.
{T}: Add {C}.
{2}, {T}: Choose a color. Add an amount of mana of that color equal to the number of creatures you control of the chosen type.

Glacial Fortress

This land enters tapped unless you control a Plains or an Island.
{T}: Add {W} or {U}.

Reflecting Pool

{T}: Add one mana of any type that a land you control could produce.

Prairie Stream

({T}: Add {W} or {U}.)
This land enters tapped unless you control two or more basic lands.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Celestial Convergence

This enchantment enters with seven omen counters on it.
At the beginning of your upkeep, remove an omen counter from this enchantment. If there are no omen counters on this enchantment, the player with the highest life total wins the game. If two or more players are tied for highest life total, the game is a draw.

Hover Barrier

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on this creature.

Arcane Adaptation

As this enchantment enters, choose a creature type.
Creatures you control are the chosen type in addition to their other types. The same is true for creature spells you control and creature cards you own that aren't on the battlefield.

Nykthos, Shrine to Nyx

{T}: Add {C}.
{2}, {T}: Choose a color. Add an amount of mana of that color equal to your devotion to that color. (Your devotion to a color is the number of mana symbols of that color in the mana costs of permanents you control.)

Griffin Aerie

At the beginning of your end step, if you gained 3 or more life this turn, create a 2/2 white Griffin creature token with flying.

Ajani's Pridemate

Whenever you gain life, put a +1/+1 counter on this creature.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

The Gaffer

At the beginning of each end step, if you gained 3 or more life this turn, draw a card.

Esper Sentinel

Whenever an opponent casts their first noncreature spell each turn, draw a card unless that player pays {X}, where X is this creature's power.

Wall of Frost

Defender
Whenever this creature blocks a creature, that creature doesn't untap during its controller's next untap step.