Skullcage

At the beginning of each opponent's upkeep, Skullcage deals 2 damage to that player unless they have exactly three or exactly four cards in hand.

Darkness

Prevent all combat damage that would be dealt this turn.

Runeflare Trap

If an opponent drew three or more cards this turn, you may pay {R} rather than pay this spell's mana cost.
Runeflare Trap deals damage to target player equal to the number of cards in that player's hand.

Darigaaz, the Igniter

Flying
Whenever Darigaaz, the Igniter deals combat damage to a player, you may pay {2}{R}. If you do, choose a color, then that player reveals their hand and Darigaaz deals damage to the player equal to the number of cards of that color revealed this way.

Misers' Cage

At the beginning of each opponent's upkeep, if that player has five or more cards in hand, Misers' Cage deals 2 damage to that player.

Wheel of Misfortune

Each player secretly chooses a number 0 or greater, then all players reveal those numbers simultaneously and determine the highest and lowest numbers revealed this way. Wheel of Misfortune deals damage equal to the highest number to each player who chose that number. Each player who didn't choose the lowest number discards their hand, then draws seven cards.

Gaze of Adamaro

Gaze of Adamaro deals damage to target player equal to the number of cards in that player's hand.

Iron Maiden

At the beginning of each opponent's upkeep, Iron Maiden deals X damage to that player, where X is the number of cards in their hand minus 4.

Black Vise

As Black Vise enters, choose an opponent.
At the beginning of the chosen player's upkeep, Black Vise deals X damage to that player, where X is the number of cards in their hand minus 4.

Kederekt Parasite

Whenever an opponent draws a card, if you control a red permanent, you may have Kederekt Parasite deal 1 damage to that player.

Chains of Mephistopheles

If a player would draw a card except the first one they draw in each of their draw steps, that player discards a card instead. If the player discards a card this way, they draw a card. If the player doesn't discard a card this way, they mill a card.

Adamaro, First to Desire

Adamaro, First to Desire's power and toughness are each equal to the number of cards in the hand of the opponent with the most cards in hand.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Wheel of Fortune

Each player discards their hand, then draws seven cards.

Ebony Owl Netsuke

At the beginning of each opponent's upkeep, if that player has seven or more cards in hand, Ebony Owl Netsuke deals 4 damage to that player.

Vicious Shadows

Whenever a creature dies, you may have Vicious Shadows deal damage to target player equal to the number of cards in that player's hand.

Dark Suspicions

At the beginning of each opponent's upkeep, that player loses X life, where X is the number of cards in that player's hand minus the number of cards in your hand.

Sword of War and Peace

Equipped creature gets +2/+2 and has protection from red and from white.
Whenever equipped creature deals combat damage to a player, Sword of War and Peace deals damage to that player equal to the number of cards in their hand and you gain 1 life for each card in your hand.
Equip {2}

Molten Psyche

Each player shuffles the cards from their hand into their library, then draws that many cards.
Metalcraft — If you control three or more artifacts, Molten Psyche deals damage to each opponent equal to the number of cards that player has drawn this turn.

Chandra Ablaze

+1: Discard a card. If a red card is discarded this way, Chandra Ablaze deals 4 damage to any target.
−2: Each player discards their hand, then draws three cards.
−7: Cast any number of red instant and/or sorcery cards from your graveyard without paying their mana costs.

Anvil of Bogardan

Players have no maximum hand size.
At the beginning of each player's draw step, that player draws an additional card, then discards a card.

Sudden Impact

Sudden Impact deals damage to target player equal to the number of cards in that player's hand.

Spiteful Visions

At the beginning of each player's draw step, that player draws an additional card.
Whenever a player draws a card, Spiteful Visions deals 1 damage to that player.