Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Dimir House Guard

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
Sacrifice a creature: Regenerate Dimir House Guard.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Profane Tutor

Suspend 2—{1}{B} (Rather than cast this card from your hand, pay {1}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search your library for a card, put that card into your hand, then shuffle.

Neutralize

Counter target spell.
Cycling {2} ({2}, Discard this card: Draw a card.)

Drogskol Reaver

Flying, double strike, lifelink
Whenever you gain life, draw a card.

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Trazyn the Infinite

Deathtouch
Prismatic Gallery — As long as Trazyn the Infinite is on the battlefield, it has all activated abilities of all artifact cards in your graveyard.

Dark Ritual

Gravecrawler

Gravecrawler can't block.
You may cast Gravecrawler from your graveyard as long as you control a Zombie.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

The One Ring

Indestructible
When The One Ring enters, if you cast it, you gain protection from everything until your next turn.
At the beginning of your upkeep, you lose 1 life for each burden counter on The One Ring.
{T}: Put a burden counter on The One Ring, then draw a card for each burden counter on The One Ring.

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

God-Pharaoh's Statue

Spells your opponents cast cost {2} more to cast.
At the beginning of your end step, each opponent loses 1 life.

Myr Welder

Imprint — {T}: Exile target artifact card from a graveyard.
Myr Welder has all activated abilities of all cards exiled with it.

Mystical Tutor

Search your library for an instant or sorcery card, reveal it, then shuffle and put that card on top.

Greed

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Spelltithe Enforcer

Whenever an opponent casts a spell, that player sacrifices a permanent unless they pay {1}.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Precognitive Perception

Draw three cards.
Addendum — If you cast this spell during your main phase, instead scry 3, then draw three cards.

Miscalculation

Counter target spell unless its controller pays {2}.
Cycling {2} ({2}, Discard this card: Draw a card.)

Fracture

Destroy target artifact, enchantment, or planeswalker.

Ensnaring Bridge

Creatures with power greater than the number of cards in your hand can't attack.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Dizzy Spell

Target creature gets -3/-0 until end of turn.
Transmute {1}{U}{U} ({1}{U}{U}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Arcane Sanctum

Arcane Sanctum enters tapped.
{T}: Add {W}, {U}, or {B}.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Mortify

Clutch of the Undercity

Return target permanent to its owner's hand. Its controller loses 3 life.
Transmute {1}{U}{B} ({1}{U}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Purity

Flying
If noncombat damage would be dealt to you, prevent that damage. You gain life equal to the damage prevented this way.
When Purity is put into a graveyard from anywhere, shuffle it into its owner's library.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Defiler of Flesh

Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Oloro, Ageless Ascetic

At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro, Ageless Ascetic is in the command zone, you gain 2 life.

Perplex

Counter target spell unless its controller discards their hand.
Transmute {1}{U}{B} ({1}{U}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Soulless Jailer

Permanent cards in graveyards can't enter the battlefield.
Players can't cast noncreature spells from graveyards or exile.

Muddle the Mixture

Counter target instant or sorcery spell.
Transmute {1}{U}{U} ({1}{U}{U}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Basilisk Collar

Equipped creature has deathtouch and lifelink.
Equip {2}

Mana Leak

Counter target spell unless its controller pays {3}.

Viscera Seer

Sacrifice a creature: Scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Ashnod's Altar

Light of Promise

Enchant creature
Enchanted creature has "Whenever you gain life, put that many +1/+1 counters on this creature."

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.

Ponder

Look at the top three cards of your library, then put them back in any order. You may shuffle.
Draw a card.

Karn's Touch

Target noncreature artifact becomes an artifact creature with power and toughness each equal to its mana value until end of turn. (It retains its abilities.)

Sol Ring

Dimir Signet

Shred Memory

Exile up to four target cards from a single graveyard.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Norn's Annex

({W/P} can be paid with either {W} or 2 life.)
Creatures can't attack you or planeswalkers you control unless their controller pays {W/P} for each of those creatures.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Aven Mindcensor

Flash
Flying
If an opponent would search a library, that player searches the top four cards of that library instead.

Mystic Remora

Cumulative upkeep {1} (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
Whenever an opponent casts a noncreature spell, you may draw a card unless that player pays {4}.

Netherborn Phalanx

When Netherborn Phalanx enters, each opponent loses 1 life for each creature they control.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then then shuffle. Transmute only as a sorcery.)

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Negate

Ethereal Usher

{U}, {T}: Target creature can't be blocked this turn.
Transmute {1}{U}{U} ({1}{U}{U}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Render Silent

Counter target spell. Its controller can't cast spells this turn.

Will, Scion of Peace

Vigilance
{T}: Spells you cast this turn that are white and/or blue cost {X} less to cast, where X is the amount of life you gained this turn. Activate only as a sorcery.

Crush Contraband

Choose one or both —
• Exile target artifact.
• Exile target enchantment.

Leshrac's Sigil

Whenever an opponent casts a green spell, you may pay {B}{B}. If you do, look at that player's hand and choose a card from it. The player discards that card.
{B}{B}: Return Leshrac's Sigil to its owner's hand.

Queza, Augur of Agonies

Whenever you draw a card, target opponent loses 1 life and you gain 1 life.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Orzhov Signet

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this artifact: Add one mana of any color.")

No Mercy

Whenever a creature deals damage to you, destroy it.

Hushbringer

Flying, lifelink
Creatures entering or dying don't cause abilities to trigger.

Boon Reflection

If you would gain life, you gain twice that much life instead.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Drift of Phantasms

Defender (This creature can't attack.)
Flying
Transmute {1}{U}{U} ({1}{U}{U}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Silence

Your opponents can't cast spells this turn.

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Smokestack

At the beginning of your upkeep, you may put a soot counter on Smokestack.
At the beginning of each player's upkeep, that player sacrifices a permanent for each soot counter on Smokestack.

Grozoth

Defender (This creature can't attack.)
When Grozoth enters, you may search your library for any number of cards that have mana value 9, reveal them, put them into your hand, then shuffle.
{4}: Grozoth loses defender until end of turn.
Transmute {1}{U}{U} ({1}{U}{U}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

Sydri, Galvanic Genius

{U}: Target noncreature artifact becomes an artifact creature with power and toughness each equal to its mana value until end of turn.
{W}{B}: Target artifact creature gains deathtouch and lifelink until end of turn.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Arcane Signet

Xenic Poltergeist

{T}: Until your next upkeep, target noncreature artifact becomes an artifact creature with power and toughness each equal to its mana value.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Crookclaw Transmuter

Flash
Flying
When Crookclaw Transmuter enters, switch target creature's power and toughness until end of turn.

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

Crested Sunmare

Other Horses you control have indestructible.
At the beginning of each end step, if you gained life this turn, create a 5/5 white Horse creature token.

Cradle of Vitality

Whenever you gain life, you may pay {1}{W}. If you do, put a +1/+1 counter on target creature for each 1 life you gained.

Surge of Salvation

You and permanents you control gain hexproof until end of turn. Prevent all damage that black and/or red sources would deal to creatures you control this turn.

Brainspoil

Destroy target creature that isn't enchanted. It can't be regenerated.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Fellwar Stone

Windborn Muse

Flying
Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Katsumasa, the Animator

Flying
{2}{U}: Until end of turn, target noncreature artifact you control becomes an artifact creature and gains flying. If it's not a Vehicle, it has base power and toughness 1/1 until end of turn.
At the beginning of your upkeep, put a +1/+1 counter on each of up to three target noncreature artifacts.

Azorius Signet

Tolaria West

Tolaria West enters tapped.
{T}: Add {U}.
Transmute {1}{U}{U} ({1}{U}{U}, Discard this card: Search your library for a card with mana value 0, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Dimir Machinations

Look at the top three cards of target player's library. Exile any number of those cards, then put the rest back in any order.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Carrion Feeder

Carrion Feeder can't block.
Sacrifice a creature: Put a +1/+1 counter on Carrion Feeder.

Grand Arbiter Augustin IV

White spells you cast cost {1} less to cast.
Blue spells you cast cost {1} less to cast.
Spells your opponents cast cost {1} more to cast.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Winter Orb

As long as Winter Orb is untapped, players can't untap more than one land during their untap steps.

Chromatic Lantern

Lands you control have "{T}: Add one mana of any color."
{T}: Add one mana of any color.

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Karn, the Great Creator

Activated abilities of artifacts your opponents control can't be activated.
+1: Until your next turn, up to one target noncreature artifact becomes an artifact creature with power and toughness each equal to its mana value.
−2: You may reveal an artifact card you own from outside the game or choose a face-up artifact card you own in exile. Put that card into your hand.