Myrkul, Lord of Bones

As long as your life total is less than or equal to half your starting life total, Myrkul, Lord of Bones has indestructible.
Whenever another nontoken creature you control dies, you may exile it. If you do, create a token that's a copy of that card, except it's an enchantment and loses all other card types.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Anointed Procession

If an effect would create one or more tokens under your control, it creates twice that many of those tokens instead.

Archon of Sun's Grace

Flying, lifelink
Pegasus creatures you control have lifelink.
Constellation — Whenever an enchantment you control enters, create a 2/2 white Pegasus creature token with flying.

Assassin's Trophy

Destroy target permanent an opponent controls. Its controller may search their library for a basic land card, put it onto the battlefield, then shuffle.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Avacyn's Pilgrim

Barrenton Medic

{T}: Prevent the next 1 damage that would be dealt to any target this turn.
Put a -1/-1 counter on Barrenton Medic: Untap Barrenton Medic.

Bayou

Beast Within

Destroy target permanent. Its controller creates a 3/3 green Beast creature token.

Beledros Witherbloom

Flying
At the beginning of each upkeep, create a 1/1 black and green Pest creature token with "When this creature dies, you gain 1 life."
Pay 10 life: Untap all lands you control. Activate only once each turn.

Birds of Paradise

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Boseiju, Who Endures

{T}: Add {G}.
Channel — {1}{G}, Discard Boseiju, Who Endures: Destroy target artifact, enchantment, or nonbasic land an opponent controls. That player may search their library for a land card with a basic land type, put it onto the battlefield, then shuffle. This ability costs {1} less to activate for each legendary creature you control.

Bountiful Promenade

Bountiful Promenade enters tapped unless you have two or more opponents.
{T}: Add {G} or {W}.

Celestine, the Living Saint

Flying, lifelink
Healing Tears — At the beginning of your end step, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the amount of life you gained this turn.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Cruel Celebrant

Whenever Cruel Celebrant or another creature or planeswalker you control dies, each opponent loses 1 life and you gain 1 life.

Cultivate

Search your library for up to two basic land cards, reveal those cards, put one onto the battlefield tapped and the other into your hand, then shuffle.

Delighted Halfling

{T}: Add {C}.
{T}: Add one mana of any color. Spend this mana only to cast a legendary spell, and that spell can't be countered.

Devoted Druid

{T}: Add {G}.
Put a -1/-1 counter on Devoted Druid: Untap Devoted Druid.

Dina, Soul Steeper

Whenever you gain life, each opponent loses 1 life.
{1}, Sacrifice another creature: Dina, Soul Steeper gets +X/+0 until end of turn, where X is the sacrificed creature's power.

Eidolon of Blossoms

Constellation — Whenever Eidolon of Blossoms or another enchantment you control enters, draw a card.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Elves of Deep Shadow

{T}: Add {B}. Elves of Deep Shadow deals 1 damage to you.

Essence Warden

Whenever another creature enters, you gain 1 life.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Forest

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters, you may pay 2 life. If you don't, it enters tapped.

Heroic Intervention

Permanents you control gain hexproof and indestructible until end of turn.

High Market

{T}: Add {C}.
{T}, Sacrifice a creature: You gain 1 life.

Indatha Triome

({T}: Add {W}, {B}, or {G}.)
Indatha Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Jaheira, Friend of the Forest

Tokens you control have "{T}: Add {G}."
Choose a Background (You can have a Background as a second commander.)

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Kambal, Profiteering Mayor

Whenever one or more tokens your opponents control enter, for each of them, create a tapped token that's a copy of it. This ability triggers only once each turn.
Whenever one or more tokens you control enter, each opponent loses 1 life and you gain 1 life.

Kodama's Reach

Llanowar Elves

Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Mondrak, Glory Dominus

If one or more tokens would be created under your control, twice that many of those tokens are created instead.
{1}{W/P}{W/P}, Sacrifice two other artifacts and/or creatures: Put an indestructible counter on Mondrak, Glory Dominus. ({W/P} can be paid with either {W} or 2 life.)

Nature's Lore

Search your library for a Forest card, put that card onto the battlefield, then shuffle.

Overgrown Tomb

({T}: Add {B} or {G}.)
As Overgrown Tomb enters, you may pay 2 life. If you don't, it enters tapped.

Parallel Lives

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Phyrexian Tower

{T}: Add {C}.
{T}, Sacrifice a creature: Add {B}{B}.

Plains

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Sanctum Weaver

{T}: Add X mana of any one color, where X is the number of enchantments you control.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Savannah

Scrubland

Setessan Champion

Constellation — Whenever an enchantment you control enters, put a +1/+1 counter on Setessan Champion and draw a card.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Soul Warden

Soul's Attendant

Whenever another creature enters, you may gain 1 life.

Sterling Grove

Other enchantments you control have shroud. (They can't be the targets of spells or abilities.)
{1}, Sacrifice Sterling Grove: Search your library for an enchantment card, reveal it, then shuffle and put that card on top.

Sunpetal Grove

Sunpetal Grove enters tapped unless you control a Forest or a Plains.
{T}: Add {G} or {W}.

Suture Priest

Whenever another creature you control enters, you may gain 1 life.
Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Swamp

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Sylvan Library

At the beginning of your draw step, you may draw two additional cards. If you do, choose two cards in your hand drawn this turn. For each of those cards, pay 4 life or put the card on top of your library.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Temple Garden

({T}: Add {G} or {W}.)
As Temple Garden enters, you may pay 2 life. If you don't, it enters tapped.

The Gaffer

At the beginning of each end step, if you gained 3 or more life this turn, draw a card.

Three Visits

Search your library for a Forest card, put it onto the battlefield, then shuffle.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Underground Mortuary

({T}: Add {B} or {G}.)
Underground Mortuary enters tapped.
When Underground Mortuary enters, surveil 1. (Look at the top card of your library. You may put it into your graveyard.)

Undergrowth Stadium

Undergrowth Stadium enters tapped unless you have two or more opponents.
{T}: Add {B} or {G}.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Vault of Champions

Vault of Champions enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Viscera Seer

Sacrifice a creature: Scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Woodland Cemetery

Woodland Cemetery enters tapped unless you control a Swamp or a Forest.
{T}: Add {B} or {G}.

Yavimaya, Cradle of Growth

Each land is a Forest in addition to its other land types.

Zulaport Cutthroat

Whenever Zulaport Cutthroat or another creature you control dies, each opponent loses 1 life and you gain 1 life.

Talisman of Unity

{T}: Add {C}.
{T}: Add {G} or {W}. Talisman of Unity deals 1 damage to you.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Talisman of Resilience

{T}: Add {C}.
{T}: Add {B} or {G}. Talisman of Resilience deals 1 damage to you.

Overgrown Farmland

Overgrown Farmland enters tapped unless you control two or more other lands.
{T}: Add {G} or {W}.

Deathcap Glade

Deathcap Glade enters tapped unless you control two or more other lands.
{T}: Add {B} or {G}.

Llanowar Wastes

{T}: Add {C}.
{T}: Add {B} or {G}. Llanowar Wastes deals 1 damage to you.

Shattered Sanctum

Shattered Sanctum enters tapped unless you control two or more other lands.
{T}: Add {W} or {B}.

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. Caves of Koilos deals 1 damage to you.

Sandsteppe Citadel

Sandsteppe Citadel enters tapped.
{T}: Add {W}, {B}, or {G}.

Brushland

{T}: Add {C}.
{T}: Add {G} or {W}. Brushland deals 1 damage to you.

Demolition Field

{T}: Add {C}.
{2}, {T}, Sacrifice Demolition Field: Destroy target nonbasic land an opponent controls. That land's controller may search their library for a basic land card, put it onto the battlefield, then shuffle. You may search your library for a basic land card, put it onto the battlefield, then shuffle.