Sludge Monster

Whenever Sludge Monster enters or attacks, put a slime counter on up to one other target creature.
Non-Horror creatures with slime counters on them lose all abilities and have base power and toughness 2/2.

Massacre Wurm

When this creature enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Black Sun's Zenith

Put X -1/-1 counters on each creature. Shuffle Black Sun's Zenith into its owner's library.

Typhoid Rats

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)

Glistening Deluge

All creatures get -1/-1 until end of turn. Creatures that are green and/or white get an additional -2/-2 until end of turn.

Crippling Blight

Enchant creature
Enchanted creature gets -1/-1 and can't block.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Toxrill, the Corrosive

At the beginning of each end step, put a slime counter on each creature you don't control.
Creatures you don't control get -1/-1 for each slime counter on them.
Whenever a creature you don't control with a slime counter on it dies, create a 1/1 black Slug creature token.
{U}{B}, Sacrifice a Slug: Draw a card.

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Grim Affliction

Put a -1/-1 counter on target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Kaervek, the Spiteful

Festergloom

Nonblack creatures get -1/-1 until end of turn.

Festering March

Creatures your opponents control get -1/-1 until end of turn. Exile Festering March with three time counters on it.
Suspend 3—{2}{B} (Rather than cast this card from your hand, you may pay {2}{B} and exile it with three time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)

Crumbling Ashes

At the beginning of your upkeep, destroy target creature with a -1/-1 counter on it.

Clawing Torment

Enchant artifact or creature
As long as enchanted permanent is a creature, it gets -1/-1 and can't block.
Enchanted permanent has "At the beginning of your upkeep, you lose 1 life."

Night of Souls' Betrayal

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Festering Mummy

When Festering Mummy dies, you may put a -1/-1 counter on target creature.

Ascendant Evincar

Flying (This creature can't be blocked except by creatures with flying or reach.)
Other black creatures get +1/+1.
Nonblack creatures get -1/-1.

Bogbrew Witch

{2}, {T}: Search your library for a card named Festering Newt or Bubbling Cauldron, put it onto the battlefield tapped, then shuffle.

Festering Newt

When Festering Newt dies, target creature an opponent controls gets -1/-1 until end of turn. That creature gets -4/-4 instead if you control a creature named Bogbrew Witch.

Noxious Field

Enchant land
Enchanted land has "{T}: This land deals 1 damage to each creature and each player."

Massacre Girl, Known Killer

Menace
Creatures you control have wither. (They deal damage to creatures in the form of -1/-1 counters.)
Whenever a creature an opponent controls dies, if its toughness was less than 1, draw a card.

Fume Spitter

Sacrifice Fume Spitter: Put a -1/-1 counter on target creature.

Grim Physician

When Grim Physician dies, target creature an opponent controls gets -1/-1 until end of turn.

Blowfly Infestation

Whenever a creature dies, if it had a -1/-1 counter on it, put a -1/-1 counter on target creature.

Gnawing Vermin

When Gnawing Vermin enters, target player mills two cards.
When Gnawing Vermin dies, target creature you don't control gets -1/-1 until end of turn.

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Cower in Fear

Creatures your opponents control get -1/-1 until end of turn.

Maha, Its Feathers Night

Flying, trample
Ward—Discard a card.
Creatures your opponents control have base toughness 1.

Grasping Dunes

{T}: Add {C}.
{1}, {T}, Sacrifice Grasping Dunes: Put a -1/-1 counter on target creature. Activate only as a sorcery.

Bubbling Cauldron

{1}, {T}, Sacrifice a creature: You gain 4 life.
{1}, {T}, Sacrifice a creature named Festering Newt: Each opponent loses 4 life. You gain life equal to the life lost this way.

Doomwake Giant

Constellation — Whenever Doomwake Giant or another enchantment you control enters, creatures your opponents control get -1/-1 until end of turn.