Quietus Spike

Equipped creature has deathtouch.
Whenever equipped creature deals combat damage to a player, that player loses half their life, rounded up.
Equip {3}

Ramses, Assassin Lord

Deathtouch
Other Assassins you control get +1/+1.
Whenever a player loses the game, if they were attacked this turn by an Assassin you controlled, you win the game.

Mystical Tutor

Search your library for an instant or sorcery card, reveal it, then shuffle and put that card on top.

Aqueous Form

Enchant creature
Enchanted creature can't be blocked.
Whenever enchanted creature attacks, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Arcane Denial

Counter target spell. Its controller may draw up to two cards at the beginning of the next turn's upkeep.
You draw a card at the beginning of the next turn's upkeep.

Smoke Bomb

Flash
All creatures have shroud. (They can't be the targets of spells or abilities.)
At the beginning of your upkeep, sacrifice Smoke Bomb. When you do, target creature you control can't be blocked this turn.

Hookblade Veteran

During your turn, Hookblade Veteran has flying. (It can't be blocked except by creatures with flying or reach.)

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Virtus the Veiled

Partner with Gorm the Great (When this creature enters, target player may put Gorm into their hand from their library, then shuffle.)
Deathtouch
Whenever Virtus the Veiled deals combat damage to a player, that player loses half their life, rounded up.

Achilles Davenport

Freerunning {U}{B} (You may cast this spell for its freerunning cost if you dealt combat damage to a player this turn with an Assassin or commander.)
Menace (This creature can't be blocked except by two or more creatures.)
Other Assassins you control get +1/+1.

Back in Town

Return X target outlaw creature cards from your graveyard to the battlefield. (Assassins, Mercenaries, Pirates, Rogues, and Warlocks are outlaws.)

Hired Poisoner

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Chain Assassination

Freerunning {1}{B} (You may cast this spell for its freerunning cost if you dealt combat damage to a player this turn with an Assassin or commander.)
Destroy target creature. If another creature died this turn, draw a card.

Ezio, Blade of Vengeance

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Whenever an Assassin you control deals combat damage to a player, draw a card.

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Pongify

Destroy target creature. It can't be regenerated. Its controller creates a 3/3 green Ape creature token.

Jacob Frye

Partner with Evie Frye (When this creature enters, target player may put Evie into their hand from their library, then shuffle.)
Whenever one or more Assassins you control deal combat damage to a player, exile up to one target Assassin card or card with freerunning from your graveyard. If you do, copy it. You may cast the copy.

Platinum Angel

Flying
You can't lose the game and your opponents can't win the game.

Island

Fierce Guardianship

If you control a commander, you may cast this spell without paying its mana cost.
Counter target noncreature spell.

Aetherize

Return all attacking creatures to their owner's hand.

Infernal Grasp

Destroy target creature. You lose 2 life.

Changeling Outcast

Changeling (This card is every creature type.)
Changeling Outcast can't block and can't be blocked.

Force of Negation

If it's not your turn, you may exile a blue card from your hand rather than pay this spell's mana cost.
Counter target noncreature spell. If that spell is countered this way, exile it instead of putting it into its owner's graveyard.

Big Game Hunter

When Big Game Hunter enters, destroy target creature with power 4 or greater. It can't be regenerated.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Assassin Initiate

{1}: Assassin Initiate gains your choice of flying, deathtouch, or lifelink until end of turn.

Mana Drain

Counter target spell. At the beginning of your next main phase, add an amount of {C} equal to that spell's mana value.

Swamp

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this artifact: Add one mana of any color.")

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Pact of Negation

Counter target spell.
At the beginning of your next upkeep, pay {3}{U}{U}. If you don't, you lose the game.

Desmond Miles

Menace
Desmond Miles gets +1/+0 for each other Assassin you control and each Assassin card in your graveyard.
Whenever Desmond Miles deals combat damage to a player, surveil X, where X is the amount of damage it dealt to that player.

Dimir Signet

Callidus Assassin

Flash
Polymorphine — You may have Callidus Assassin enter tapped as a copy of any creature on the battlefield, except it has "When this creature enters, destroy up to one other target creature with the same name as this creature."

Evie Frye

Partner with Jacob Frye (When this creature enters, target player may put Jacob into their hand from their library, then shuffle.)
{1}, {T}: Draw a card, then discard a card. When you discard a creature card this way, target creature you control can't be blocked this turn.

Rapid Hybridization

Destroy target creature. It can't be regenerated. That creature's controller creates a 3/3 green Frog Lizard creature token.

The Golden Throne

Arcane Life-support — If you would lose the game, instead exile The Golden Throne and your life total becomes 1.
A Thousand Souls Die Every Day — {T}, Sacrifice a creature: Add three mana in any combination of colors.

Royal Assassin

Sol Ring

Counterspell

Desynchronization

Return each nonland permanent that's not historic to its owner's hand. (Artifacts, legendaries, and Sagas are historic.)

Go for the Throat

Termination Facilitator

{T}: Put a bounty counter on target creature or planeswalker. Activate only as a sorcery.
Whenever a creature or planeswalker an opponent controls with a bounty counter on it is dealt damage, destroy it.

Nekrataal

First strike
When Nekrataal enters, destroy target nonartifact, nonblack creature. That creature can't be regenerated.

Brotherhood Spy

At the beginning of combat on your turn, if you control a legendary Assassin, Brotherhood Spy gets +1/+0 until end of turn and can't be blocked this turn.

Lydia Frye

Lydia Frye can't be blocked by creatures with power 3 or greater.
At the beginning of your end step, surveil X, where X is the number of tapped Assassins you control. (Look at the top X cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Negate

Dispel

Swan Song

Counter target enchantment, instant, or sorcery spell. Its controller creates a 2/2 blue Bird creature token with flying.

Midnight Assassin

Eagle Vision

Freerunning {1}{U} (You may cast this spell for its freerunning cost if you dealt combat damage to a player this turn with an Assassin or commander.)
Draw three cards.

Escape Detection

Freerunning—Return a blue creature you control to its owner's hand. (You may cast this spell for its freerunning cost if you dealt combat damage to a player this turn with an Assassin or commander.)
Return target creature to its owner's hand.
Draw a card.

Drown in the Loch

Choose one —
• Counter target spell with mana value less than or equal to the number of cards in its controller's graveyard.
• Destroy target creature with mana value less than or equal to the number of cards in its controller's graveyard.

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Countersquall

Counter target noncreature spell. Its controller loses 2 life.

Lich's Mirror

If you would lose the game, instead shuffle your hand, your graveyard, and all permanents you own into your library, then draw seven cards and your life total becomes 20.

Brotherhood Patriarch

When Brotherhood Patriarch dies, each opponent loses 2 life and you gain 2 life.

Etrata, the Silencer

Etrata, the Silencer can't be blocked.
Whenever Etrata deals combat damage to a player, exile target creature that player controls and put a hit counter on that card. That player loses the game if they own three or more exiled cards with hit counters on them. Etrata's owner shuffles Etrata into their library.

Mari, the Killing Quill

Whenever a creature an opponent controls dies, exile it with a hit counter on it.
Assassins, Mercenaries, and Rogues you control have deathtouch and "Whenever this creature deals combat damage to a player, you may remove a hit counter from a card that player owns in exile. If you do, draw a card and create two Treasure tokens."

Become Anonymous

Exile target nontoken creature you own and the top two cards of your library in a face-down pile, shuffle that pile, then cloak those cards. They enter tapped. (To cloak a card, put it onto the battlefield face down as a 2/2 creature with ward {2}. Turn it face up any time for its mana cost if it's a creature card.)

Assassin Gauntlet

When Assassin Gauntlet enters, attach it to up to one target creature you control. Tap all creatures target opponent controls.
Equipped creature gets +1/+1 and has "Whenever this creature deals combat damage to a player, draw a card, then discard a card."
Equip {2}