Auriok Champion

Protection from black and from red
Whenever another creature enters, you may gain 1 life.

Demon's Horn

Whenever a player casts a black spell, you may gain 1 life.

Dragon's Claw

Whenever a player casts a red spell, you may gain 1 life.

Thunderstaff

As long as Thunderstaff is untapped, if a creature would deal combat damage to you, prevent 1 of that damage.
{2}, {T}: Attacking creatures get +1/+0 until end of turn.

Urza's Armor

If a source would deal damage to you, prevent 1 of that damage.

Boon Reflection

If you would gain life, you gain twice that much life instead.

Fire Diamond

Fire Diamond enters tapped.
{T}: Add {R}.

Bilbo, Birthday Celebrant

If you would gain life, you gain that much life plus 1 instead.
{2}{W}{B}{G}, {T}, Exile Bilbo, Birthday Celebrant: Search your library for any number of creature cards, put them onto the battlefield, then shuffle. Activate only if you have 111 or more life.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Ivory Tower

At the beginning of your upkeep, you gain X life, where X is the number of cards in your hand minus 4.

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Norn's Annex

({W/P} can be paid with either {W} or 2 life.)
Creatures can't attack you or planeswalkers you control unless their controller pays {W/P} for each of those creatures.

Forced Fruition

Whenever an opponent casts a spell, that player draws seven cards.

Charcoal Diamond

Charcoal Diamond enters tapped.
{T}: Add {B}.

Sky Diamond

Ob Nixilis of the Black Oath

+2: Each opponent loses 1 life. You gain life equal to the life lost this way.
−2: Create a 5/5 black Demon creature token with flying. You lose 2 life.
−8: You get an emblem with "{1}{B}, Sacrifice a creature: You gain X life and draw X cards, where X is the sacrificed creature's power."
Ob Nixilis of the Black Oath can be your commander.

Kenrith, the Returned King

{R}: All creatures gain trample and haste until end of turn.
{1}{G}: Put a +1/+1 counter on target creature.
{2}{W}: Target player gains 5 life.
{3}{U}: Target player draws a card.
{4}{B}: Put target creature card from a graveyard onto the battlefield under its owner's control.

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Kraken's Eye

Whenever a player casts a blue spell, you may gain 1 life.

Horizon Chimera

Flash
Flying, trample
Whenever you draw a card, you gain 1 life.

Staff of the Wild Magus

Whenever you cast a green spell or a Forest you control enters, you gain 1 life.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Golem's Heart

Whenever a player casts an artifact spell, you may gain 1 life.

Moss Diamond

Moss Diamond enters tapped.
{T}: Add {G}.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Sigarda's Splendor

As Sigarda's Splendor enters, note your life total.
At the beginning of your upkeep, draw a card if your life total is greater than or equal to the last noted life total for Sigarda's Splendor. Then note your life total.
Whenever you cast a white spell, you gain 1 life.

Staff of the Mind Magus

Whenever you cast a blue spell or an Island you control enters, you gain 1 life.

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis, the Hate-Twisted deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Essence Warden

Whenever another creature enters, you gain 1 life.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.

Venser's Journal

You have no maximum hand size.
At the beginning of your upkeep, you gain 1 life for each card in your hand.

Well of Ideas

When Well of Ideas enters, draw two cards.
At the beginning of each other player's draw step, that player draws an additional card.
At the beginning of your draw step, draw two additional cards.

Nekusar, the Mindrazer

At the beginning of each player's draw step, that player draws an additional card.
Whenever an opponent draws a card, Nekusar, the Mindrazer deals 1 damage to that player.

Soul's Attendant

Whenever another creature enters, you may gain 1 life.

Lifegift

Whenever a land enters, you may gain 1 life.

Ob Nixilis Reignited

+1: You draw a card and you lose 1 life.
−3: Destroy target creature.
−8: Target opponent gets an emblem with "Whenever a player draws a card, you lose 2 life."

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

On the Trail

Whenever you draw your second card each turn, you may put a land card from your hand onto the battlefield tapped.

Darksteel Reactor

Indestructible (Effects that say "destroy" don't destroy this artifact.)
At the beginning of your upkeep, you may put a charge counter on Darksteel Reactor.
When Darksteel Reactor has twenty or more charge counters on it, you win the game.

Marble Diamond

Marble Diamond enters tapped.
{T}: Add {W}.

Phyrexian Tyranny

Whenever a player draws a card, that player loses 2 life unless they pay {2}.

Profane Memento

Whenever a creature card is put into an opponent's graveyard from anywhere, you gain 1 life.

Staff of the Sun Magus

Whenever you cast a white spell or a Plains you control enters, you gain 1 life.

Soul Warden

Valkmira, Protector's Shield

If a source an opponent controls would deal damage to you or a permanent you control, prevent 1 of that damage.
Whenever you or another permanent you control becomes the target of a spell or ability an opponent controls, counter that spell or ability unless its controller pays {1}.

Reidane, God of the Worthy

Flying, vigilance
Snow lands your opponents control enter tapped.
Noncreature spells your opponents cast with mana value 4 or greater cost {2} more to cast.

Reidane, God of the Worthy // Valkmira, Protector's Shield

Orbs of Warding

You have hexproof. (You can't be the target of spells or abilities your opponents control.)
If a creature would deal damage to you, prevent 1 of that damage.

Staff of the Death Magus

Whenever you cast a black spell or a Swamp you control enters, you gain 1 life.

Knight of Dawn's Light

First strike
If you would gain life, you gain that much life plus 1 instead.
{1}{W}: Knight of Dawn's Light gets +1/+1 until end of turn.

Wurm's Tooth

Whenever a player casts a green spell, you may gain 1 life.

Angel's Feather

Whenever a player casts a white spell, you may gain 1 life.

Wilderness Reclamation

At the beginning of your end step, untap all lands you control.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Helix Pinnacle

Shroud (This enchantment can't be the target of spells or abilities.)
{X}: Put X tower counters on Helix Pinnacle.
At the beginning of your upkeep, if there are 100 or more tower counters on Helix Pinnacle, you win the game.

Ivory Crane Netsuke

At the beginning of your upkeep, if you have seven or more cards in hand, you gain 4 life.

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

The Gaffer

At the beginning of each end step, if you gained 3 or more life this turn, draw a card.

Spiteful Visions

At the beginning of each player's draw step, that player draws an additional card.
Whenever a player draws a card, Spiteful Visions deals 1 damage to that player.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.