Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

Cunning Lethemancer

At the beginning of your upkeep, each player discards a card.

Innocent Blood

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Dictate of Kruphix

Flash
At the beginning of each player's draw step, that player draws an additional card.

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Delirium Skeins

Blood-Toll Harpy

Flying
When Blood-Toll Harpy enters the battlefield, each player loses 1 life.

Blood Clock

At the beginning of each player's upkeep, that player returns a permanent they control to its owner's hand unless they pay 2 life.

Deathcurse Ogre

When Deathcurse Ogre dies, each player loses 3 life.

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Butcher of Malakir

Flying
Whenever Butcher of Malakir or another creature you control dies, each opponent sacrifices a creature.

Archfiend of Depravity

Flying
At the beginning of each opponent's end step, that player chooses up to two creatures they control, then sacrifices the rest.

Umbilicus

At the beginning of each player's upkeep, that player may pay 2 life. If they don't, they return a permanent they control to its owner's hand.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Share the Spoils

When Share the Spoils enters the battlefield or an opponent loses the game, exile the top card of each player's library.
During each player's turn, that player may play a land or cast a spell from among cards exiled with Share the Spoils, and they may spend mana as though it were mana of any color to cast that spell. When they do, exile the top card of their library.

Clockwork Fox

When Clockwork Fox leaves the battlefield, you draw two cards and each opponent draws a card.

Festering Evil

At the beginning of your upkeep, Festering Evil deals 1 damage to each creature and each player.
{B}{B}, Sacrifice Festering Evil: It deals 3 damage to each creature and each player.

Reign of the Pit

Each player sacrifices a creature. Create an X/X black Demon creature token with flying, where X is the total power of the creatures sacrificed this way.

Day's Undoing

Each player shuffles their hand and graveyard into their library, then draws seven cards. If it's your turn, end the turn. (Exile all spells and abilities from the stack, including this card. Discard down to your maximum hand size. Damage wears off, and "this turn" and "until end of turn" effects end.)

Citadel of Pain

At the beginning of each player's end step, Citadel of Pain deals X damage to that player, where X is the number of untapped lands they control.

Burglar Rat

When Burglar Rat enters the battlefield, each opponent discards a card.

Bringer of the Last Gift

Flying
When Bringer of the Last Gift enters the battlefield, if you cast it, each player sacrifices all other creatures they control. Then each player returns all creature cards from their graveyard that weren't put there this way to the battlefield.

Cackling Fiend

When Cackling Fiend enters the battlefield, each opponent discards a card.

Howling Banshee

Flying
When Howling Banshee enters the battlefield, each player loses 3 life.

Urborg Stalker

At the beginning of each player's upkeep, if that player controls a nonblack, nonland permanent, Urborg Stalker deals 1 damage to that player.

Miasmic Mummy

When Miasmic Mummy enters the battlefield, each player discards a card.

Font of Mythos

At the beginning of each player's draw step, that player draws two additional cards.

Plague Spitter

At the beginning of your upkeep, Plague Spitter deals 1 damage to each creature and each player.
When Plague Spitter dies, it deals 1 damage to each creature and each player.

Demon's Disciple

When Demon's Disciple enters the battlefield, each player sacrifices a creature or planeswalker.

Roiling Vortex

At the beginning of each player's upkeep, Roiling Vortex deals 1 damage to them.
Whenever a player casts a spell, if no mana was spent to cast that spell, Roiling Vortex deals 5 damage to that player.
{R}: Your opponents can't gain life this turn.

Court of Ambition

When Court of Ambition enters the battlefield, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Magma Giant

When Magma Giant enters the battlefield, it deals 2 damage to each creature and each player.

Merciless Executioner

When Merciless Executioner enters the battlefield, each player sacrifices a creature.

Blistergrub

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
When Blistergrub dies, each opponent loses 2 life.

Elderfang Disciple

When Elderfang Disciple enters the battlefield, each opponent discards a card.

Flare of Malice

You may sacrifice a nontoken black creature rather than pay this spell's mana cost.
Each opponent sacrifices a creature or planeswalker with the greatest mana value among creatures and planeswalkers they control.

Duskmantle Seer

Flying
At the beginning of your upkeep, each player reveals the top card of their library, loses life equal to that card's mana value, then puts it into their hand.

Barter in Blood

Plaguecrafter

When Plaguecrafter enters the battlefield, each player sacrifices a creature or planeswalker. Each player who can't discards a card.

Howling Golem

Whenever Howling Golem attacks or blocks, each player draws a card.

Earsplitting Rats

When Earsplitting Rats enters the battlefield, each player discards a card.
Discard a card: Regenerate Earsplitting Rats.

Diminishing Returns

Each player shuffles their hand and graveyard into their library. You exile the top ten cards of your library. Then each player draws up to seven cards.

Spiteful Visions

At the beginning of each player's draw step, that player draws an additional card.
Whenever a player draws a card, Spiteful Visions deals 1 damage to that player.

Chain Devil

Animate Chains — When Chain Devil enters the battlefield, each player sacrifices a nontoken creature.

Collapsing Borders

Domain — At the beginning of each player's upkeep, that player gains 1 life for each basic land type among lands they control. Then Collapsing Borders deals 3 damage to that player.

Empty the Catacombs

Each player returns all creature cards from their graveyard to their hand.

Rotting Rats

When Rotting Rats enters the battlefield, each player discards a card.
Unearth {1}{B} ({1}{B}: Return this card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step or if it would leave the battlefield. Unearth only as a sorcery.)

Dire Fleet Ravager

Menace, deathtouch
When Dire Fleet Ravager enters the battlefield, each player loses a third of their life, rounded up.

Call to the Grave

At the beginning of each player's upkeep, that player sacrifices a non-Zombie creature.
At the beginning of the end step, if no creatures are on the battlefield, sacrifice Call to the Grave.

Bellowing Mauler

At the beginning of your end step, each player loses 4 life unless they sacrifice a nontoken creature.

Inferno

Inferno deals 6 damage to each creature and each player.

Breath of Malfegor

Breath of Malfegor deals 5 damage to each opponent.

Dusk Mangler

As an additional cost to cast this spell, sacrifice a creature, discard a card, or pay 4 life.
When Dusk Mangler enters the battlefield, each opponent sacrifices a creature, discards a card, and loses 4 life.

Slum Reaper

When Slum Reaper enters the battlefield, each player sacrifices a creature.

Crimson Honor Guard

Trample
At the beginning of each player's end step, Crimson Honor Guard deals 4 damage to that player unless they control a commander.

Patriarch's Bidding

Each player chooses a creature type. Each player returns all creature cards of a type chosen this way from their graveyard to the battlefield.

Elvish Doomsayer

When Elvish Doomsayer dies, each opponent discards a card.

Molten Psyche

Each player shuffles the cards from their hand into their library, then draws that many cards.
Metalcraft — If you control three or more artifacts, Molten Psyche deals damage to each opponent equal to the number of cards that player has drawn this turn.

Boldwyr Heavyweights

Trample
When Boldwyr Heavyweights enters the battlefield, each opponent may search their library for a creature card and put it onto the battlefield. Then each player who searched their library this way shuffles.

Accursed Marauder

When Accursed Marauder enters the battlefield, each player sacrifices a nontoken creature.

Maggot Carrier

When Maggot Carrier enters the battlefield, each player loses 1 life.

Fleshbag Marauder

When Fleshbag Marauder enters the battlefield, each player sacrifices a creature.

Baneful Omen

At the beginning of your end step, you may reveal the top card of your library. If you do, each opponent loses life equal to that card's mana value.

Doomsday Excruciator

Flying
When Doomsday Excruciator enters, if it was cast, each player exiles all but the bottom six cards of their library face down.
At the beginning of your upkeep, draw a card.

Havoc Festival

Players can't gain life.
At the beginning of each player's upkeep, that player loses half their life, rounded up.

Famine

Famine deals 3 damage to each creature and each player.

Earth-Cult Elemental

Siege Monster — When Earth-Cult Elemental enters the battlefield, roll a d20.
1—9 | Each player sacrifices a permanent.
10—19 | Each opponent sacrifices a permanent.
20 | Each opponent sacrifices two permanents.

Brotherhood Patriarch

When Brotherhood Patriarch dies, each opponent loses 2 life and you gain 2 life.

Abyssal Gorestalker

When Abyssal Gorestalker enters the battlefield, each player sacrifices two creatures.

Caustic Hound

When Caustic Hound dies, each player loses 4 life.

Mana Cache

At the beginning of each player's end step, put a charge counter on Mana Cache for each untapped land that player controls.
Remove a charge counter from Mana Cache: Add {C}. Any player may activate this ability but only during their turn before the end step.

Descent into Avernus

At the beginning of your upkeep, put two descent counters on Descent into Avernus. Then each player creates X Treasure tokens and Descent into Avernus deals X damage to each player, where X is the number of descent counters on Descent into Avernus.

Dreamborn Muse

At the beginning of each player's upkeep, that player mills X cards, where X is the number of cards in their hand.

Rivalry

At the beginning of each player's upkeep, if that player controls more lands than each other player, Rivalry deals 2 damage to them.

Urza's Guilt

Each player draws two cards, then discards three cards, then loses 4 life.

Dark Suspicions

At the beginning of each opponent's upkeep, that player loses X life, where X is the number of cards in that player's hand minus the number of cards in your hand.

Rabid Bloodsucker

Flying (This creature can't be blocked except by creatures with flying or reach.)
When Rabid Bloodsucker enters the battlefield, each player loses 2 life.

Necrotic Hex

Each player sacrifices six creatures. You create six tapped 2/2 black Zombie creature tokens.

Flamebreak

Flamebreak deals 3 damage to each creature without flying and each player. Creatures dealt damage this way can't be regenerated this turn.

Price of Progress

Price of Progress deals damage to each player equal to twice the number of nonbasic lands that player controls.

Abyssal Gatekeeper

When Abyssal Gatekeeper dies, each player sacrifices a creature.

Ancient Runes

At the beginning of each player's upkeep, Ancient Runes deals damage to that player equal to the number of artifacts they control.

Stormfist Crusader

Menace
At the beginning of your upkeep, each player draws a card and loses 1 life.

Underworld Cerberus

Underworld Cerberus can't be blocked except by three or more creatures.
Cards in graveyards can't be the targets of spells or abilities.
When Underworld Cerberus dies, exile it and each player returns all creature cards from their graveyard to their hand.

Call to the Void

Each player secretly chooses a creature they control and a creature they don't control. Then those choices are revealed. Destroy each creature chosen this way.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Etched Familiar

When Etched Familiar dies, each opponent loses 2 life and you gain 2 life.

Magus of the Abyss

At the beginning of each player's upkeep, destroy target nonartifact creature that player controls of their choice. It can't be regenerated.

Crack the Earth

Antagonism

At the beginning of each player's end step, Antagonism deals 2 damage to that player unless one of their opponents was dealt damage this turn.

Blood Tithe

Each opponent loses 3 life. You gain life equal to the life lost this way.

Marching Duodrone

Whenever Marching Duodrone attacks, each player creates a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Lim-Dûl's Hex

At the beginning of your upkeep, for each player, Lim-Dûl's Hex deals 1 damage to that player unless they pay {B} or {3}.

Creeping Dread

At the beginning of your upkeep, each player discards a card. Each opponent who discarded a card that shares a card type with the card you discarded loses 3 life. (Players reveal the discarded cards simultaneously.)

Howling Mine

At the beginning of each player's draw step, if Howling Mine is untapped, that player draws an additional card.

Sulfuric Vortex

At the beginning of each player's upkeep, Sulfuric Vortex deals 2 damage to that player.
If a player would gain life, that player gains no life instead.

Flame Rift

Flame Rift deals 4 damage to each player.

Vision Skeins

Fevered Visions

At the beginning of each player's end step, that player draws a card. If the player is your opponent and has four or more cards in hand, Fevered Visions deals 2 damage to that player.

Forsaken Wastes

Players can't gain life.
At the beginning of each player's upkeep, that player loses 1 life.
Whenever Forsaken Wastes becomes the target of a spell, that spell's controller loses 5 life.

Gravelighter

Flying
When Gravelighter enters the battlefield, draw a card if a creature died this turn. Otherwise, each player sacrifices a creature.

Fractured Sanity

Each opponent mills fourteen cards.
Cycling {1}{U} ({1}{U}, Discard this card: Draw a card.)
When you cycle Fractured Sanity, each opponent mills four cards.