False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Cabal Ritual

Add {B}{B}{B}.
Threshold — Add {B}{B}{B}{B}{B} instead if seven or more cards are in your graveyard.

Reprieve

Return target spell to its owner's hand.
Draw a card.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Insatiable Avarice

Spree (Choose one or more additional costs.)
+ {2} — Search your library for a card, then shuffle and put that card on top.
+ {B}{B} — Target player draws three cards and loses 3 life.

Dark Ritual

Temple of Silence

Temple of Silence enters tapped.
When Temple of Silence enters, scry 1.
{T}: Add {W} or {B}.

Faith's Shield

Target permanent you control gains protection from the color of your choice until end of turn.
Fateful hour — If you have 5 or less life, instead you and each permanent you control gain protection from the color of your choice until end of turn.

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Warlock Class

(Gain the next level as a sorcery to add its ability.)
At the beginning of your end step, if a creature died this turn, each opponent loses 1 life.
{1}{B}: Level 2
When this Class becomes level 2, look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
{6}{B}: Level 3
At the beginning of your end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Flagstones of Trokair

{T}: Add {W}.
When Flagstones of Trokair is put into a graveyard from the battlefield, you may search your library for a Plains card, put it onto the battlefield tapped, then shuffle.

Life Insurance

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever a nontoken creature dies, you lose 1 life and create a Treasure token.

Hedron Archive

{T}: Add {C}{C}.
{2}, {T}, Sacrifice Hedron Archive: Draw two cards.

Holy Day

Prevent all combat damage that would be dealt this turn.

Animate Dead

Enchant creature card in a graveyard
When Animate Dead enters, if it's on the battlefield, it loses "enchant creature card in a graveyard" and gains "enchant creature put onto the battlefield with Animate Dead." Return enchanted creature card to the battlefield under your control and attach Animate Dead to it. When Animate Dead leaves the battlefield, that creature's controller sacrifices it.
Enchanted creature gets -1/-0.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Condemn

Put target attacking creature on the bottom of its owner's library. Its controller gains life equal to its toughness.

Desolate Mire

Grimclimb Pathway

Brightclimb Pathway

Brightclimb Pathway // Grimclimb Pathway

Profane Insight

You draw a card and you lose 1 life. (Then exile this card. You may cast the creature later from exile.)

Foulmire Knight

Foulmire Knight // Profane Insight

Keen Duelist

At the beginning of your upkeep, you and target opponent each reveal the top card of your library. You each lose life equal to the mana value of the card revealed by the other player. You each put the card you revealed into your hand.

Tainted Field

{T}: Add {C}.
{T}: Add {W} or {B}. Activate only if you control a Swamp.

Plunge into Darkness

Choose one —
• Sacrifice any number of creatures. You gain 3 life for each creature sacrificed this way.
• Pay any amount of life, then look at that many cards from the top of your library. Put one of those cards into your hand and exile the rest.
Entwine {B} (Choose both if you pay the entwine cost.)

Soul Shatter

Each opponent sacrifices a creature or planeswalker with the highest mana value among creatures and planeswalkers they control.

Glacial Chasm

Cumulative upkeep—Pay 2 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
When Glacial Chasm enters, sacrifice a land.
Creatures you control can't attack.
Prevent all damage that would be dealt to you.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Hatred

As an additional cost to cast this spell, pay X life.
Target creature gets +X/+0 until end of turn.

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Wrath of God

Destroy all creatures. They can't be regenerated.

Defiler of Faith

Vigilance
As an additional cost to cast white permanent spells, you may pay 2 life. Those spells cost {W} less to cast if you paid life this way. This effect reduces only the amount of white mana you pay.
Whenever you cast a white permanent spell, create a 1/1 white Soldier creature token.

Restless Fortress

Restless Fortress enters tapped.
{T}: Add {W} or {B}.
{2}{W}{B}: Restless Fortress becomes a 1/4 white and black Nightmare creature until end of turn. It's still a land.
Whenever Restless Fortress attacks, defending player loses 2 life and you gain 2 life.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Shadowy Backstreet

({T}: Add {W} or {B}.)
Shadowy Backstreet enters tapped.
When Shadowy Backstreet enters, surveil 1. (Look at the top card of your library. You may put it into your graveyard.)

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Rout

You may cast Rout as though it had flash if you pay {2} more to cast it. (You may cast it any time you could cast an instant.)
Destroy all creatures. They can't be regenerated.

Lapse of Certainty

Counter target spell. If that spell is countered this way, put it on top of its owner's library instead of into that player's graveyard.

Phyrexian Reclamation

{1}{B}, Pay 2 life: Return target creature card from your graveyard to your hand.

Final Showdown

Spree (Choose one or more additional costs.)
+ {1} — All creatures lose all abilities until end of turn.
+ {1} — Choose a creature you control. It gains indestructible until end of turn.
+ {3}{W}{W} — Destroy all creatures.

Grafdigger's Cage

Creature cards in graveyards and libraries can't enter the battlefield.
Players can't cast spells from graveyards or libraries.

Mirror Universe

{T}, Sacrifice Mirror Universe: Exchange life totals with target opponent. Activate only during your upkeep.

White Orchid Phantom

Flying, first strike
When White Orchid Phantom enters, destroy up to one target nonbasic land. Its controller may search their library for a basic land card, put it onto the battlefield tapped, then shuffle.

Aura Blast

Loran's Escape

Target artifact or creature gains hexproof and indestructible until end of turn. Scry 1.

Mother of Runes

{T}: Target creature you control gains protection from the color of your choice until end of turn.

Hour of Revelation

This spell costs {3} less to cast if there are ten or more nonland permanents on the battlefield.
Destroy all nonland permanents.

Razaketh's Rite

Search your library for a card, put that card into your hand, then shuffle.
Cycling {B} ({B}, Discard this card: Draw a card.)

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Lively Dirge

Spree (Choose one or more additional costs.)
+ {1} — Search your library for a card, put it into your graveyard, then shuffle.
+ {2} — Return up to two creature cards with total mana value 4 or less from your graveyard to the battlefield.

Tinybones, the Pickpocket

Deathtouch
Whenever Tinybones, the Pickpocket deals combat damage to a player, you may cast target nonland permanent card from that player's graveyard, and mana of any type can be spent to cast that spell.

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Temple of Aclazotz

(Transforms from Arguel's Blood Fast.)
{T}: Add {B}.
{T}, Sacrifice a creature: You gain life equal to the sacrificed creature's toughness.

Arguel's Blood Fast

{1}{B}, Pay 2 life: Draw a card.
At the beginning of your upkeep, if you have 5 or less life, you may transform Arguel's Blood Fast.

Arguel's Blood Fast // Temple of Aclazotz

Wall of Reverence

Defender, flying
At the beginning of your end step, you may gain life equal to the power of target creature you control.

Plague of Vermin

Starting with you, each player may pay any amount of life. Repeat this process until no one pays life. Each player creates a 1/1 black Rat creature token for each 1 life they paid this way.

Succumb to Temptation

Marble Diamond

Marble Diamond enters tapped.
{T}: Add {W}.

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revival // Revenge

Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)

Ocelot Pride

First strike, lifelink
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your end step, if you gained life this turn, create a 1/1 white Cat creature token. Then if you have the city's blessing, for each token you control that entered this turn, create a token that's a copy of it.

Doomsday

Search your library and graveyard for five cards and exile the rest. Put the chosen cards on top of your library in any order. You lose half your life, rounded up.

Enlightened Tutor

Search your library for an artifact or enchantment card, reveal it, then shuffle and put that card on top.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Weathered Wayfarer

{W}, {T}: Search your library for a land card, reveal it, put it into your hand, then shuffle. Activate only if an opponent controls more lands than you.

Shambling Vent

Shambling Vent enters tapped.
{T}: Add {W} or {B}.
{1}{W}{B}: Shambling Vent becomes a 2/3 white and black Elemental creature with lifelink until end of turn. It's still a land.

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Death Grasp

Death Grasp deals X damage to any target. You gain X life.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Pain's Reward

Each player may bid life. You start the bidding with a bid of any number. In turn order, each player may top the high bid. The bidding ends if the high bid stands. The high bidder loses life equal to the high bid and draws four cards.

Wall of Shards

Defender, flying
Cumulative upkeep—An opponent gains 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Children of Korlis

Sacrifice Children of Korlis: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Soul Rend

Destroy target creature if it's white. A creature destroyed this way can't be regenerated.
Draw a card at the beginning of the next turn's upkeep.

Sunlit Marsh

({T}: Add {W} or {B}.)
Sunlit Marsh enters tapped.

Temporal Aperture

{5}, {T}: Shuffle your library, then reveal the top card. Until end of turn, for as long as that card remains on top of your library, play with the top card of your library revealed and you may play that card without paying its mana cost. (If it has X in its mana cost, X is 0.)

Planar Collapse

At the beginning of your upkeep, if there are four or more creatures on the battlefield, sacrifice Planar Collapse and destroy all creatures. They can't be regenerated.

Scrubland

Vona, Butcher of Magan

Vigilance, lifelink
{T}, Pay 7 life: Destroy target nonland permanent. Activate only during your turn.

Thriving Heath

Thriving Heath enters tapped. As it enters, choose a color other than white.
{T}: Add {W} or one mana of the chosen color.

Intervention Pact

The next time a source of your choice would deal damage to you this turn, prevent that damage. You gain life equal to the damage prevented this way.
At the beginning of your next upkeep, pay {1}{W}{W}. If you don't, you lose the game.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Inner Sanctum

Cumulative upkeep—Pay 2 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
Prevent all damage that would be dealt to creatures you control.

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Sign in Blood

Target player draws two cards and loses 2 life.

Pest Control

Destroy all nonland permanents with mana value 1 or less.
Cycling {2} ({2}, Discard this card: Draw a card.)

Aurora of Emrakul

Flying, deathtouch
Whenever Aurora of Emrakul attacks, each opponent loses 3 life.

Cryptolith Fragment

Cryptolith Fragment enters tapped.
{T}: Add one mana of any color. Each player loses 1 life.
At the beginning of your upkeep, if each player has 10 or less life, transform Cryptolith Fragment.

Cryptolith Fragment // Aurora of Emrakul

Hex Parasite

{X}{B/P}: Remove up to X counters from target permanent. For each counter removed this way, Hex Parasite gets +1/+0 until end of turn. ({B/P} can be paid with either {B} or 2 life.)

Bloodgift Demon

Flying
At the beginning of your upkeep, target player draws a card and loses 1 life.

Moonlight Bargain

Look at the top five cards of your library. For each card, put that card into your graveyard unless you pay 2 life. Then put the rest into your hand.

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Plains

Vindicate

Ancient Tomb

{T}: Add {C}{C}. Ancient Tomb deals 2 damage to you.

Rowan's Grim Search

Bargain (You may sacrifice an artifact, enchantment, or token as you cast this spell.)
If this spell was bargained, look at the top four cards of your library, then put up to two of them back on top of your library in any order and the rest into your graveyard.
You draw two cards and you lose 2 life.