Prisoner's Dilemma

Each opponent secretly chooses silence or snitch, then the choices are revealed. If each opponent chose silence, Prisoner's Dilemma deals 4 damage to each of them. If each opponent chose snitch, Prisoner's Dilemma deals 8 damage to each of them. Otherwise, Prisoner's Dilemma deals 12 damage to each opponent who chose silence.
Flashback {5}{R}{R}

Moonsilver Key

{1}, {T}, Sacrifice Moonsilver Key: Search your library for an artifact card with a mana ability or a basic land card, reveal it, put it into your hand, then shuffle.

Secrets of the Key

Investigate. If this spell was cast from a graveyard, investigate twice instead. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")
Flashback {3}{U}

Staff of Eden, Vault's Key

When Staff of Eden, Vault's Key enters, put target legendary permanent card not named Staff of Eden, Vault's Key from a graveyard onto the battlefield under your control.
{T}: Draw a card for each permanent you control but don't own.

Diviner's Lockbox

{1}, {T}: Choose a card name, then reveal the top card of your library. If that card has the chosen name, sacrifice Diviner's Lockbox and draw three cards. Activate only as a sorcery.

Galvanic Key

Monkey Cage

When a creature enters, sacrifice Monkey Cage and create X 2/2 green Monkey creature tokens, where X is that creature's mana value.

Doc Aurlock, Grizzled Genius

Spells you cast from your graveyard or from exile cost {2} less to cast.
Plotting cards from your hand costs {2} less.

Slickshot Vault-Buster

Vigilance
Slickshot Vault-Buster gets +2/+0 as long as you've committed a crime this turn. (Targeting opponents, anything they control, and/or cards in their graveyards is a crime.)

Key to the City

{T}, Discard a card: Up to one target creature can't be blocked this turn.
Whenever Key to the City becomes untapped, you may pay {2}. If you do, draw a card.

Locked in the Cemetery

Enchant creature
When Locked in the Cemetery enters, if there are five or more cards in your graveyard, tap enchanted creature.
Enchanted creature doesn't untap during its controller's untap step.

Phyrexian Vault

{2}, {T}, Sacrifice a creature: Draw a card.

Voltaic Key

Chain Reaction

Chain Reaction deals X damage to each creature, where X is the number of creatures on the battlefield.

Reckless Lackey

First strike, haste
{2}{R}, Sacrifice Reckless Lackey: Draw a card and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Free the Fae

Mill four cards. Then put an instant, sorcery, or Faerie card from among the milled cards into your hand.

Picklock Prankster

Picklock Prankster // Free the Fae

Case of the Locked Hothouse

You may play an additional land on each of your turns.
To solve — You control seven or more lands. (If unsolved, solve at the beginning of your end step.)
Solved — You may look at the top card of your library any time, and you may play lands and cast creature and enchantment spells from the top of your library.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Gridlock

Vault of Catlacan

(Transforms from Storm the Vault.)
{T}: Add one mana of any color.
{T}: Add {U} for each artifact you control.

Storm the Vault

Whenever one or more creatures you control deal combat damage to a player, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
At the beginning of your end step, if you control five or more artifacts, transform Storm the Vault.

Storm the Vault // Vault of Catlacan

You Find Some Prisoners

Choose one —
• Break Their Chains — Destroy target artifact.
• Interrogate Them — Exile the top three cards of target opponent's library. Choose one of them. Until the end of your next turn, you may play that card, and you may spend mana as though it were mana of any color to cast it.

The Key to the Vault

Whenever equipped creature deals combat damage to a player, look at that many cards from the top of your library. You may exile a nonland card from among them. Put the rest on the bottom of your library in a random order. You may cast the exiled card without paying its mana cost.
Equip {2}{U}

Simic Locket

{T}: Add {G} or {U}.
{G/U}{G/U}{G/U}{G/U}, {T}, Sacrifice Simic Locket: Draw two cards.

Vault 21: House Gambit

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I, II — Discard a card, then draw a card.
III — Reveal up to five nonland cards from your hand. For each of those cards that has the same mana value as another card revealed this way, create a Treasure token.

Helvault

{1}, {T}: Exile target creature you control.
{7}, {T}: Exile target creature you don't control.
When Helvault is put into a graveyard from the battlefield, return all cards exiled with it to the battlefield under their owners' control.

Lockjaw Snapper

Wither (This deals damage to creatures in the form of -1/-1 counters.)
When Lockjaw Snapper dies, put a -1/-1 counter on each creature with a -1/-1 counter on it.

Keymaster Rogue

Keymaster Rogue can't be blocked.
When Keymaster Rogue enters, return a creature you control to its owner's hand.

Simic Keyrune

{T}: Add {G} or {U}.
{G}{U}: Simic Keyrune becomes a 2/3 green and blue Crab artifact creature with hexproof until end of turn. (It can't be the target of spells or abilities your opponents control.)

Mystery Key

When equipped creature deals combat damage to a player, sacrifice Mystery Key. If you do, draw three cards.
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Vault 112: Sadistic Simulation

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I, II — Tap up to one target creature and put a stun counter on it. You get {E}{E} (two energy counters).
III — Pay any amount of {E}. If you paid one or more {E} this way, shuffle your library, then exile that many cards from the top. You may play one of those cards without paying its mana cost.

Goblin Chainwhirler

First strike
When Goblin Chainwhirler enters, it deals 1 damage to each opponent and each creature and planeswalker they control.

Chain Lightning

Chain Lightning deals 3 damage to any target. Then that player or that permanent's controller may pay {R}{R}. If the player does, they may copy this spell and may choose a new target for that copy.

Wastes

Loot, the Key to Everything

Ward {1}
At the beginning of your upkeep, exile the top X cards of your library, where X is the number of card types among other nonland permanents you control. You may play those cards this turn.

Chain of Plasma

Chain of Plasma deals 3 damage to any target. Then that player or that permanent's controller may discard a card. If the player does, they may copy this spell and may choose a new target for that copy.

Wrathful Jailbreaker

Wrathful Jailbreaker attacks each combat if able.
Nightbound (If a player casts at least two spells during their own turn, it becomes day next turn.)

Weary Prisoner

Defender
Daybound (If a player casts no spells during their own turn, it becomes night next turn.)

Weary Prisoner // Wrathful Jailbreaker

Uro, Titan of Nature's Wrath

When Uro enters, sacrifice it unless it escaped.
Whenever Uro enters or attacks, you gain 3 life and draw a card, then you may put a land card from your hand onto the battlefield.
Escape—{G}{G}{U}{U}, Exile five other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Karn Liberated

+4: Target player exiles a card from their hand.
−3: Exile target permanent.
−14: Restart the game, leaving in exile all non-Aura permanent cards exiled with Karn Liberated. Then put those cards onto the battlefield under your control.

Vault 87: Forced Evolution

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Gain control of target non-Mutant creature for as long as you control Vault 87.
II — Put a +1/+1 counter on target creature you control. It becomes a Mutant in addition to its other types.
III — Draw cards equal to the greatest power among Mutants you control.

Skeleton Key

Equipped creature has skulk. (It can't be blocked by creatures with greater power.)
Whenever equipped creature deals combat damage to a player, you may draw a card. If you do, discard a card.
Equip {2}

Mindlock Orb

Betrayal at the Vault

Target creature you control deals damage equal to its power to each of two other target creatures.

Gruul Keyrune

{T}: Add {R} or {G}.
{R}{G}: Gruul Keyrune becomes a 3/2 red and green Beast artifact creature with trample until end of turn.

Ox of Agonas

When Ox of Agonas enters, discard your hand, then draw three cards.
Escape—{R}{R}, Exile eight other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)
Ox of Agonas escapes with a +1/+1 counter on it.

Spectral Prison

Enchant creature
Enchanted creature doesn't untap during its controller's untap step.
When enchanted creature becomes the target of a spell, sacrifice Spectral Prison.

Manifold Key

{1}, {T}: Untap another target artifact.
{3}, {T}: Target creature can't be blocked this turn.

Treasure Vault

{T}: Add {C}.
{X}{X}, {T}, Sacrifice Treasure Vault: Create X Treasure tokens.

Bloodbraid Challenger

Cascade
Haste
Escape—{3}{R}{G}, Exile three other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Slickshot Lockpicker

When Slickshot Lockpicker enters, target instant or sorcery card in your graveyard gains flashback until end of turn. The flashback cost is equal to its mana cost. (You may cast that card from your graveyard for its flashback cost. Then exile it.)
Plot {2}{U} (You may pay {2}{U} and exile this card from your hand. Cast it as a sorcery on a later turn without paying its mana cost. Plot only as a sorcery.)

Perilous Vault

{5}, {T}, Exile Perilous Vault: Exile all nonland permanents.

Izzet Locket

{T}: Add {U} or {R}.
{U/R}{U/R}{U/R}{U/R}, {T}, Sacrifice Izzet Locket: Draw two cards.

Escape Tunnel

{T}, Sacrifice Escape Tunnel: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.
{T}, Sacrifice Escape Tunnel: Target creature with power 2 or less can't be blocked this turn.

Thought Prison

Imprint — When Thought Prison enters, you may have target player reveal their hand. If you do, choose a nonland card from it and exile that card.
Whenever a player casts a spell that shares a color or mana value with the exiled card, Thought Prison deals 2 damage to that player.

Deadlock Trap

Deadlock Trap enters tapped.
When Deadlock Trap enters, you get {E}{E} (two energy counters).
{T}, Pay {E}: Tap target creature or planeswalker. Its activated abilities can't be activated this turn.

Sol Ring

Lock and Load

Draw a card, then draw a card for each other instant and sorcery spell you've cast this turn.
Plot {3}{U} (You may pay {3}{U} and exile this card from your hand. Cast it as a sorcery on a later turn without paying its mana cost. Plot only as a sorcery.)

Mana Chains

Enchant creature
Enchanted creature has "Cumulative upkeep {1}." (At the beginning of its controller's upkeep, that player puts an age counter on it, then sacrifices it unless they pay its upkeep cost for each age counter on it.)

Sealock Monster

Sealock Monster can't attack unless defending player controls an Island.
{5}{U}{U}: Monstrosity 3. (If this creature isn't monstrous, put three +1/+1 counters on it and it becomes monstrous.)
When Sealock Monster becomes monstrous, target land becomes an Island in addition to its other types.

Izzet Keyrune

{T}: Add {U} or {R}.
{U}{R}: Until end of turn, Izzet Keyrune becomes a 2/1 blue and red Elemental artifact creature.
Whenever Izzet Keyrune deals combat damage to a player, you may draw a card. If you do, discard a card.

Warden of the Chained

Trample
Warden of the Chained can't attack unless you control another creature with power 4 or greater.

Collector's Vault

{2}, {T}: Draw a card, then discard a card. Create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Escape Artist

Escape Artist can't be blocked.
{U}, Discard a card: Return Escape Artist to its owner's hand.

Imprisoned in the Moon

Enchant creature, land, or planeswalker
Enchanted permanent is a colorless land with "{T}: Add {C}" and loses all other card types and abilities.

Lunar Hatchling

Flying, trample
Basic landcycling {2} ({2}, Discard this card: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.)
Escape—{4}{G}{U}, Exile a land you control, Exile five other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Oracle's Vault

{2}, {T}: Exile the top card of your library. Until end of turn, you may play that card. Put a brick counter on Oracle's Vault.
{T}: Exile the top card of your library. Until end of turn, you may play that card without paying its mana cost. Activate only if there are three or more brick counters on Oracle's Vault.

Chain of Acid

Destroy target noncreature permanent. Then that permanent's controller may copy this spell and may choose a new target for that copy.

Keeper of Keys

When Keeper of Keys enters, you become the monarch.
At the beginning of your upkeep, if you're the monarch, creatures you control can't be blocked this turn.

Cloud Key

As Cloud Key enters, choose artifact, creature, enchantment, instant, or sorcery.
Spells you cast of the chosen type cost {1} less to cast.

Goblin Locksmith

Whenever Goblin Locksmith attacks, creatures with defender can't block this turn.

Skyway Robber

Flying
Escape—{3}{U}, Exile five other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)
Skyway Robber escapes with "Whenever Skyway Robber deals combat damage to a player, you may cast an artifact, instant, or sorcery spell from among cards exiled with Skyway Robber without paying its mana cost."

Gruul Locket

{T}: Add {R} or {G}.
{R/G}{R/G}{R/G}{R/G}, {T}, Sacrifice Gruul Locket: Draw two cards.