Essence Flux

Exile target creature you control, then return that card to the battlefield under its owner's control. If it's a Spirit, put a +1/+1 counter on it.

Clutch of the Undercity

Return target permanent to its owner's hand. Its controller loses 3 life.
Transmute {1}{U}{B} ({1}{U}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Undermine

Counter target spell. Its controller loses 3 life.

Panharmonicon

If an artifact or creature entering causes a triggered ability of a permanent you control to trigger, that ability triggers an additional time.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Underground River

{T}: Add {C}.
{T}: Add {U} or {B}. Underground River deals 1 damage to you.

Profane Command

Choose two —
• Target player loses X life.
• Return target creature card with mana value X or less from your graveyard to the battlefield.
• Target creature gets -X/-X until end of turn.
• Up to X target creatures gain fear until end of turn. (They can't be blocked except by artifact creatures and/or black creatures.)

Leyline of Anticipation

If Leyline of Anticipation is in your opening hand, you may begin the game with it on the battlefield.
You may cast spells as though they had flash.

Temple of Deceit

Temple of Deceit enters tapped.
When Temple of Deceit enters, scry 1.
{T}: Add {U} or {B}.

Seer's Lantern

{T}: Add {C}.
{2}, {T}: Scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Thassa, Deep-Dwelling

Indestructible
As long as your devotion to blue is less than five, Thassa isn't a creature.
At the beginning of your end step, exile up to one other target creature you control, then return that card to the battlefield under your control.
{3}{U}: Tap another target creature.

Thirst for Knowledge

Draw three cards. Then discard two cards unless you discard an artifact card.

Dire Fleet Ravager

Menace, deathtouch
When Dire Fleet Ravager enters, each player loses a third of their life, rounded up.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters, you may pay 2 life. If you don't, it enters tapped.

Howling Banshee

Flying
When Howling Banshee enters, each player loses 3 life.

Laquatus's Champion

When Laquatus's Champion enters, target player loses 6 life.
When Laquatus's Champion leaves the battlefield, that player gains 6 life.
{B}: Regenerate Laquatus's Champion.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters tapped unless you control two or more basic lands.

Urza's Guilt

Each player draws two cards, then discards three cards, then loses 4 life.

Narset's Reversal

Copy target instant or sorcery spell, then return it to its owner's hand. You may choose new targets for the copy.

Sword-Point Diplomacy

Reveal the top three cards of your library. For each of those cards, put that card into your hand unless any opponent pays 3 life. Then exile the rest.

Phyrexian Metamorph

({U/P} can be paid with either {U} or 2 life.)
You may have Phyrexian Metamorph enter as a copy of any artifact or creature on the battlefield, except it's an artifact in addition to its other types.

Sovereign's Bite

Target player loses 3 life and you gain 3 life.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Sygg, River Cutthroat

At the beginning of each end step, if an opponent lost 3 or more life this turn, you may draw a card. (Damage causes loss of life.)

Ashiok, Dream Render

Spells and abilities your opponents control can't cause their controller to search their library.
−1: Target player mills four cards. Then exile each opponent's graveyard.

Ravenous Chupacabra

When Ravenous Chupacabra enters, destroy target creature an opponent controls.

Vampire Sovereign

Flying
When Vampire Sovereign enters, target opponent loses 3 life and you gain 3 life.

Island

Ob Nixilis, the Fallen

Landfall — Whenever a land you control enters, you may have target player lose 3 life. If you do, put three +1/+1 counters on Ob Nixilis, the Fallen.

Loyal Subordinate

Menace (This creature can't be blocked except by two or more creatures.)
Lieutenant — At the beginning of combat on your turn, if you control your commander, each opponent loses 3 life.

Dimir Signet

Baleful Strix

Flying, deathtouch
When Baleful Strix enters, draw a card.

Solemn Simulacrum

When Solemn Simulacrum enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When Solemn Simulacrum dies, you may draw a card.

Netherborn Phalanx

When Netherborn Phalanx enters, each opponent loses 1 life for each creature they control.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then then shuffle. Transmute only as a sorcery.)

Swamp

Massacre Wurm

When Massacre Wurm enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Pierce Strider

When Pierce Strider enters, target opponent loses 3 life.

Lim-Dûl's Vault

Look at the top five cards of your library. As many times as you choose, you may pay 1 life, put those cards on the bottom of your library in any order, then look at the top five cards of your library. Then shuffle and put the last cards you looked at this way on top in any order.

Phyrexian Delver

When Phyrexian Delver enters, return target creature card from your graveyard to the battlefield. You lose life equal to that card's mana value.

Strionic Resonator

{2}, {T}: Copy target triggered ability you control. You may choose new targets for the copy. (A triggered ability uses the words "when," "whenever," or "at.")

Rite of Replication

Kicker {5} (You may pay an additional {5} as you cast this spell.)
Create a token that's a copy of target creature. If this spell was kicked, create five of those tokens instead.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Cavern Harpy

Flying
When Cavern Harpy enters, return a blue or black creature you control to its owner's hand.
Pay 1 life: Return Cavern Harpy to its owner's hand.

Preordain

Scry 2, then draw a card. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Quickling

Flash (You may cast this spell any time you could cast an instant.)
Flying
When Quickling enters, sacrifice it unless you return another creature you control to its owner's hand.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Drowned Catacomb

Drowned Catacomb enters tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

Duplicant

Imprint — When Duplicant enters, you may exile target nontoken creature.
As long as a card exiled with Duplicant is a creature card, Duplicant has the power, toughness, and creature types of the last creature card exiled with Duplicant. It's still a Shapeshifter.

Phthisis

Destroy target creature. Its controller loses life equal to its power plus its toughness.
Suspend 5—{1}{B} (Rather than cast this card from your hand, you may pay {1}{B} and exile it with five time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)

Thieving Skydiver

Kicker {X}. X can't be 0. (You may pay an additional {X} as you cast this spell.)
Flying
When Thieving Skydiver enters, if it was kicked, gain control of target artifact with mana value X or less. If that artifact is an Equipment, attach it to Thieving Skydiver.

Mirrormade

You may have Mirrormade enter as a copy of any artifact or enchantment on the battlefield.

Conjurer's Closet

At the beginning of your end step, you may exile target creature you control, then return that card to the battlefield under your control.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent or discards a card.

Dimir Locket

{T}: Add {U} or {B}.
{U/B}{U/B}{U/B}{U/B}, {T}, Sacrifice Dimir Locket: Draw two cards.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Ghostly Flicker

Exile two target artifacts, creatures, and/or lands you control, then return those cards to the battlefield under your control.

Soldevi Excavations

If Soldevi Excavations would enter, sacrifice an untapped Island instead. If you do, put Soldevi Excavations onto the battlefield. If you don't, put it into its owner's graveyard.
{T}: Add {C}{U}.
{1}, {T}: Scry 1.

Tyrant's Choice

Will of the council — Starting with you, each player votes for death or torture. If death gets more votes, each opponent sacrifices a creature. If torture gets more votes or the vote is tied, each opponent loses 4 life.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Sol Ring

Dimir Cluestone

{T}: Add {U} or {B}.
{U}{B}, {T}, Sacrifice Dimir Cluestone: Draw a card.

Mox Amber

{T}: Add one mana of any color among legendary creatures and planeswalkers you control.

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Titan Hunter

At the beginning of each player's end step, if no creatures died this turn, Titan Hunter deals 4 damage to that player.
{1}{B}, Sacrifice a creature: You gain 4 life.

Ponder

Look at the top three cards of your library, then put them back in any order. You may shuffle.
Draw a card.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Reliquary Tower

Vile Consumption

All creatures have "At the beginning of your upkeep, sacrifice this creature unless you pay 1 life."

Displace

Exile up to two target creatures you control, then return those cards to the battlefield under their owner's control.

Darkwater Catacombs

Illusionist's Stratagem

Exile up to two target creatures you control, then return those cards to the battlefield under their owner's control.
Draw a card.

Duskmantle Seer

Flying
At the beginning of your upkeep, each player reveals the top card of their library, loses life equal to that card's mana value, then puts it into their hand.