Search for Blex

Look at the top five cards of your library. You may put any number of them into your hand and the rest into your graveyard. You lose 3 life for each card you put into your hand this way.

Blex, Vexing Pest

Other Pests, Bats, Insects, Snakes, and Spiders you control get +1/+1.
When Blex, Vexing Pest dies, you gain 4 life.

Blex, Vexing Pest // Search for Blex

Fabled Passage

{T}, Sacrifice Fabled Passage: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle. Then if you control four or more lands, untap that land.

Arachnogenesis

Create X 1/2 green Spider creature tokens with reach, where X is the number of creatures attacking you. Prevent all combat damage that would be dealt this turn by non-Spider creatures.

Skyfisher Spider

Reach
When Skyfisher Spider enters, you may sacrifice another creature. When you do, destroy target nonland permanent.
When Skyfisher Spider dies, you may gain 1 life for each creature card in your graveyard. If you do, exile Skyfisher Spider from your graveyard.

Worldly Tutor

Search your library for a creature card, reveal it, then shuffle and put the card on top.

Penumbra Spider

Reach
When Penumbra Spider dies, create a 2/4 black Spider creature token with reach.

Bayou

Ishkanah, Grafwidow

Reach
Delirium — When Ishkanah, Grafwidow enters, if there are four or more card types among cards in your graveyard, create three 1/2 green Spider creature tokens with reach.
{6}{B}: Target opponent loses 1 life for each Spider you control.

Arasta of the Endless Web

Reach
Whenever an opponent casts an instant or sorcery spell, create a 1/2 green Spider creature token with reach.

Swarmyard

{T}: Add {C}.
{T}: Regenerate target Insect, Rat, Spider, or Squirrel. (The next time it would be destroyed this turn, instead tap it, remove it from combat, and heal all damage on it.)

Arachnus Web

Enchant creature
Enchanted creature can't attack or block, and its activated abilities can't be activated.
At the beginning of the end step, if enchanted creature's power is 4 or greater, destroy Arachnus Web.

Forest

Arachnus Spinner

Reach
Tap an untapped Spider you control: Search your graveyard and/or library for a card named Arachnus Web and put it onto the battlefield attached to target creature. If you search your library this way, shuffle.

Lolth, Spider Queen

Whenever a creature you control dies, put a loyalty counter on Lolth, Spider Queen.
0: You draw a card and you lose 1 life.
−3: Create two 2/1 black Spider creature tokens with menace and reach.
−8: You get an emblem with "Whenever an opponent is dealt combat damage by one or more creatures you control, if that player lost less than 8 life this turn, they lose life equal to the difference."

Rotwidow Pack

Reach
{3}{B}{G}, Exile a creature card from your graveyard: Create a 1/2 green Spider creature token with reach, then each opponent loses 1 life for each Spider you control.

Swamp

Riveteers Overlook

When Riveteers Overlook enters, sacrifice it. When you do, search your library for a basic Swamp, Mountain, or Forest card, put it onto the battlefield tapped, then shuffle and you gain 1 life.

Curse of Clinging Webs

Enchant player
Whenever a nontoken creature enchanted player controls dies, exile it and you create a 1/2 green Spider creature token with reach.

Birds of Paradise

Nyx Weaver

Reach
At the beginning of your upkeep, mill two cards. (Put the top two cards of your library into your graveyard.)
{1}{B}{G}, Exile Nyx Weaver: Return target card from your graveyard to your hand.

Shelob, Child of Ungoliant

Deathtouch, ward {2}
Other Spiders you control have deathtouch and ward {2}.
Whenever another creature dealt damage this turn by a Spider you controlled dies, create a token that's a copy of that creature, except it's a Food artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life," and it loses all other card types.

Ignoble Hierarch

Exalted (Whenever a creature you control attacks alone, that creature gets +1/+1 until end of turn.)
{T}: Add {B}, {R}, or {G}.