Damnation

Destroy all creatures. They can't be regenerated.

Foundation Breaker

When Foundation Breaker enters, you may destroy target artifact or enchantment.
Evoke {1}{G} (You may cast this spell for its evoke cost. If you do, it's sacrificed when it enters.)

Trygon Predator

Flying
Whenever this creature deals combat damage to a player, you may destroy target artifact or enchantment that player controls.

Assassin's Trophy

Destroy target permanent an opponent controls. Its controller may search their library for a basic land card, put it onto the battlefield, then shuffle.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Beast Within

Destroy target permanent. Its controller creates a 3/3 green Beast creature token.

Acidic Slime

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
When Acidic Slime enters, destroy target artifact, enchantment, or land.

Atomize

Destroy target nonland permanent. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Primaris Eliminator

When Primaris Eliminator enters, choose one —
• Executioner Round — Destroy target creature.
• Hyperfrag Round — Creatures target player controls get -2/-2 until end of turn.

Druid of Purification

When Druid of Purification enters, starting with you, each player may choose an artifact or enchantment you don't control. Destroy each permanent chosen this way.

Reclamation Sage

When this creature enters, you may destroy target artifact or enchantment.

Mandate of Abaddon

Choose target creature you control. Destroy all creatures with power less than that creature's power.

Windgrace's Judgment

For any number of opponents, destroy target nonland permanent that player controls.