Professor Onyx

Magecraft — Whenever you cast or copy an instant or sorcery spell, each opponent loses 2 life and you gain 2 life.
+1: You lose 1 life. Look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
−3: Each opponent sacrifices a creature with the greatest power among creatures that player controls.
−8: Each opponent may discard a card. If they don't, they lose 3 life. Repeat this process six more times.

Delirium Skeins

Soul Shatter

Each opponent sacrifices a creature or planeswalker with the highest mana value among creatures and planeswalkers they control.

Elderfang Disciple

When this creature enters, each opponent discards a card.

Castle Locthwain

This land enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Mind Rot

Greed

Harvest Fear

Target opponent discards two cards. (Then exile this card. You may cast the creature later from exile.)

Reaper of Night

Whenever this creature attacks, if defending player has two or fewer cards in hand, it gains flying until end of turn.

Reaper of Night // Harvest Fear

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Eliminate

Destroy target creature or planeswalker with mana value 3 or less.

Hideous End

Destroy target nonblack creature. Its controller loses 2 life.

Mind Rake

Target player discards two cards.
Overload {1}{B} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Liliana Vess

+1: Target player discards a card.
−2: Search your library for a card, then shuffle and put that card on top.
−8: Put all creature cards from all graveyards onto the battlefield under your control.

Miasmic Mummy

When this creature enters, each player discards a card.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Gray Merchant of Asphodel

When this creature enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Thoughtseize

Target player reveals their hand. You choose a nonland card from it. That player discards that card. You lose 2 life.

Sol Ring

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Court of Ambition

When this enchantment enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Viper's Kiss

Enchant creature
Enchanted creature gets -1/-1, and its activated abilities can't be activated.

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Tragic Slip

Target creature gets -1/-1 until end of turn.
Morbid — That creature gets -13/-13 until end of turn instead if a creature died this turn.

Dark Ritual

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Swamp

Liliana's Triumph

Each opponent sacrifices a creature of their choice. If you control a Liliana planeswalker, each opponent also discards a card.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Each player loses a third of their life, then discards a third of the cards in their hand, then sacrifices a third of the creatures they control of their choice, then sacrifices a third of the lands they control of their choice. Round up each time.

Go for the Throat

Burglar Rat

Myriad Landscape

This land enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice this land: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Eye Collector

Flying
Whenever this creature deals combat damage to a player, each player mills a card. (Each player puts the top card of their library into their graveyard.)

Plaguecrafter

When this creature enters, each player sacrifices a creature or planeswalker of their choice. Each player who can't discards a card.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Vermin Gorger

{T}, Sacrifice another creature: Each opponent loses 2 life and you gain 2 life.

Bone Shards

As an additional cost to cast this spell, sacrifice a creature or discard a card.
Destroy target creature or planeswalker.

Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Persist

Return target nonlegendary creature card from your graveyard to the battlefield with a -1/-1 counter on it.

Fleshbag Marauder

When this creature enters, each player sacrifices a creature of their choice.

Sign in Blood

Target player draws two cards and loses 2 life.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Diabolic Edict

Target player sacrifices a creature of their choice.

Liliana, Waker of the Dead

+1: Each player discards a card. Each opponent who can't loses 3 life.
−3: Target creature gets -X/-X until end of turn, where X is the number of cards in your graveyard.
−7: You get an emblem with "At the beginning of combat on your turn, put target creature card from a graveyard onto the battlefield under your control. It gains haste."

Tourach's Canticle

Target opponent reveals their hand. You choose a card from it. That player discards that card, then discards a card at random.

Doom Blade

Hedron Archive

{T}: Add {C}{C}.
{2}, {T}, Sacrifice this artifact: Draw two cards.

Black Cat

When this creature dies, target opponent discards a card at random.

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Innocent Blood

Each player sacrifices a creature of their choice.

Pharika's Libation

Choose one —
• Target opponent sacrifices a creature of their choice.
• Target opponent sacrifices an enchantment of their choice.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Cabal Ritual

Add {B}{B}{B}.
Threshold — Add {B}{B}{B}{B}{B} instead if seven or more cards are in your graveyard.

Death Watch

Enchant creature
When enchanted creature dies, its controller loses life equal to its power and you gain life equal to its toughness.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Archfiend of Depravity

Flying
At the beginning of each opponent's end step, that player chooses up to two creatures they control, then sacrifices the rest.

Agonizing Remorse

Target opponent reveals their hand. You choose a nonland card from it or a card from their graveyard. Exile that card. You lose 1 life.

Archon of Cruelty

Flying
Whenever this creature enters or attacks, target opponent sacrifices a creature or planeswalker of their choice, discards a card, and loses 3 life. You draw a card and gain 3 life.

Command Beacon

{T}: Add {C}.
{T}, Sacrifice this land: Put your commander into your hand from the command zone.

Hellish Rebuke

Until end of turn, permanents your opponents control gain "When this permanent deals damage to the player who cast Hellish Rebuke, sacrifice this permanent. You lose 2 life."

Tinybones Joins Up

When Tinybones Joins Up enters, any number of target players each discard a card.
Whenever a legendary creature you control enters, any number of target players each mill a card and lose 1 life.

Vona's Hunger

Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
Each opponent sacrifices a creature of their choice. If you have the city's blessing, instead each opponent sacrifices half the creatures they control of their choice, rounded up.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Tinybones, the Pickpocket

Deathtouch
Whenever Tinybones deals combat damage to a player, you may cast target nonland permanent card from that player's graveyard, and mana of any type can be spent to cast that spell.

Black Market

Whenever a creature dies, put a charge counter on this enchantment.
At the beginning of your first main phase, add {B} for each charge counter on this enchantment.

Rankle, Master of Pranks

Flying, haste
Whenever Rankle deals combat damage to a player, choose any number —
• Each player discards a card.
• Each player loses 1 life and draws a card.
• Each player sacrifices a creature of their choice.