Lupine Prototype

Lupine Prototype can't attack or block unless a player has no cards in hand.

Groundbreaker

Trample, haste
At the beginning of the end step, sacrifice Groundbreaker.

Daemogoth Woe-Eater

At the beginning of your upkeep, sacrifice a creature.
When you sacrifice Daemogoth Woe-Eater, each opponent discards a card, you draw a card, and you gain 2 life.

Phyrexian Soulgorger

Cumulative upkeep—Sacrifice a creature. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Doomgape

Trample
At the beginning of your upkeep, sacrifice a creature. You gain life equal to that creature's toughness.

Grim Giganotosaurus

{10}{B}{G}: Monstrosity 10. This ability costs {1} less to activate for each creature with power 4 or greater your opponents control. (If this creature isn't monstrous, put ten +1/+1 counters on it and it becomes monstrous.)
When Grim Giganotosaurus becomes monstrous, destroy all artifacts and creatures other than Grim Giganotosaurus.

Rumbleweed

This spell costs {1} less to cast for each land card in your graveyard.
Vigilance, reach, trample
When Rumbleweed enters, other creatures you control get +3/+3 and gain trample until end of turn.

The Gitrog, Ravenous Ride

Trample, haste
Whenever The Gitrog, Ravenous Ride deals combat damage to a player, you may sacrifice a creature that saddled it this turn. If you do, draw X cards, then put up to X land cards from your hand onto the battlefield tapped, where X is the sacrificed creature's power.
Saddle 1

Yargle and Multani

Nyxathid

As Nyxathid enters, choose an opponent.
Nyxathid gets -1/-1 for each card in the chosen player's hand.

Impervious Greatwurm

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Indestructible

Steel Leaf Champion

Steel Leaf Champion can't be blocked by creatures with power 2 or less.

Grothama, All-Devouring

Other creatures have "Whenever this creature attacks, you may have it fight Grothama, All-Devouring."
When Grothama leaves the battlefield, each player draws cards equal to the amount of damage dealt to Grothama this turn by sources they controlled.

Drinker of Sorrow

Drinker of Sorrow can't block.
Whenever Drinker of Sorrow deals combat damage, sacrifice a permanent.

Ghalta, Primal Hunger

This spell costs {X} less to cast, where X is the total power of creatures you control.
Trample

Hunted Bonebrute

Menace
When Hunted Bonebrute enters, target opponent creates two 1/1 white Dog creature tokens.
When Hunted Bonebrute dies, each opponent loses 3 life.
Disguise {1}{B}

Ghoultree

This spell costs {1} less to cast for each creature card in your graveyard.

Daemogoth Titan

Whenever Daemogoth Titan attacks or blocks, sacrifice a creature.

Sheltering Ancient

Trample
Cumulative upkeep—Put a +1/+1 counter on a creature an opponent controls. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Traxos, Scourge of Kroog

Trample
Traxos, Scourge of Kroog enters tapped and doesn't untap during your untap step.
Whenever you cast a historic spell, untap Traxos. (Artifacts, legendaries, and Sagas are historic.)

Relic Golem

Relic Golem can't attack or block unless an opponent has eight or more cards in their graveyard.
{2}, {T}: Target player mills two cards. (They put the top two cards of their library into their graveyard.)

Yargle, Glutton of Urborg

Wayward Swordtooth

Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
You may play an additional land on each of your turns.
Wayward Swordtooth can't attack or block unless you have the city's blessing.

Hunted Horror

Trample
When Hunted Horror enters, target opponent creates two 3/3 green Centaur creature tokens with protection from black.