Price of Knowledge

Players have no maximum hand size.
At the beginning of each opponent's upkeep, this enchantment deals damage to that player equal to the number of cards in that player's hand.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Infernal Grasp

Destroy target creature. You lose 2 life.

Kagemaro, First to Suffer

Kagemaro's power and toughness are each equal to the number of cards in your hand.
{B}, Sacrifice Kagemaro: All creatures get -X/-X until end of turn, where X is the number of cards in your hand.

Leaden Myr

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Blood Pact

Target player draws two cards and loses 2 life.

Fell Stinger

Deathtouch
Exploit (When this creature enters, you may sacrifice a creature.)
When this creature exploits a creature, target player draws two cards and loses 2 life.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Mikokoro, Center of the Sea

{T}: Add {C}.
{2}, {T}: Each player draws a card.

Basilica Screecher

Flying
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Baleful Mastery

You may pay {1}{B} rather than pay this spell's mana cost.
If the {1}{B} cost was paid, an opponent draws a card.
Exile target creature or planeswalker.

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Fate Unraveler

Whenever an opponent draws a card, this creature deals 1 damage to that player.

Sudden Spoiling

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Until end of turn, creatures target player controls lose all abilities and have base power and toughness 0/2.

Ivory Tower

At the beginning of your upkeep, you gain X life, where X is the number of cards in your hand minus 4.

Hero's Downfall

Rankle, Master of Pranks

Flying, haste
Whenever Rankle deals combat damage to a player, choose any number —
• Each player discards a card.
• Each player loses 1 life and draws a card.
• Each player sacrifices a creature of their choice.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice this artifact: Draw a card.

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.

Sign in Blood

Dread Presence

Whenever a Swamp you control enters, choose one —
• You draw a card and you lose 1 life.
• This creature deals 2 damage to any target and you gain 2 life.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Erebos's Intervention

Choose one —
• Target creature gets -X/-X until end of turn. You gain X life.
• Exile up to twice X target cards from graveyards.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice this artifact: Draw a card.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Howling Mine

At the beginning of each player's draw step, if this artifact is untapped, that player draws an additional card.

Gixian Puppeteer

Whenever you draw your second card each turn, each opponent loses 2 life and you gain 2 life.
When this creature dies, return another target creature card with mana value 3 or less from your graveyard to the battlefield.

Charcoal Diamond

This artifact enters tapped.
{T}: Add {B}.

Kothophed, Soul Hoarder

Flying
Whenever a permanent owned by another player is put into a graveyard from the battlefield, you draw a card and you lose 1 life.

Wayfarer's Bauble

{2}, {T}, Sacrifice this artifact: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Sol Ring

Elder Brain

Menace
Whenever this creature attacks a player, exile all cards from that player's hand, then they draw that many cards. You may play lands and cast spells from among the exiled cards for as long as they remain exiled. If you cast a spell this way, you may spend mana as though it were mana of any color to cast it.

Gray Merchant of Asphodel

When this creature enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Greed

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Zenith Chronicler

Whenever a player casts their first multicolored spell each turn, each other player draws a card.

Underworld Dreams

Whenever an opponent draws a card, this enchantment deals 1 damage to that player.

Reliquary Tower

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Swamp

Dark Ritual

Insatiable Avarice

Spree (Choose one or more additional costs.)
+ {2} — Search your library for a card, then shuffle and put that card on top.
+ {B}{B} — Target player draws three cards and loses 3 life.

Offer Immortality

Target creature gains deathtouch and indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Iron Maiden

At the beginning of each opponent's upkeep, this artifact deals X damage to that player, where X is the number of cards in their hand minus 4.

Damnable Pact

Target player draws X cards and loses X life.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature of their choice and you return up to one target creature card from your graveyard to your hand.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Doom Blade

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Howling Golem

Whenever this creature attacks or blocks, each player draws a card.

Temple Bell

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Black Vise

As this artifact enters, choose an opponent.
At the beginning of the chosen player's upkeep, this artifact deals X damage to that player, where X is the number of cards in their hand minus 4.

Veinwitch Coven

Menace
Whenever you gain life, you may pay {B}. If you do, return target creature card from your graveyard to your hand.

Noxious Gearhulk

Menace
When this creature enters, you may destroy another target creature. If a creature is destroyed this way, you gain life equal to its toughness.

Myriad Landscape

This land enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice this land: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Clockwork Fox

When this creature leaves the battlefield, you draw two cards and each opponent draws a card.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Decanter of Endless Water

You have no maximum hand size.
{T}: Add one mana of any color.

Bojuka Bog

This land enters tapped.
When this land enters, exile target player's graveyard.
{T}: Add {B}.