Zimone and Dina

Whenever you draw your second card each turn, target opponent loses 2 life and you gain 2 life.
{T}, Sacrifice another creature: Draw a card. You may put a land card from your hand onto the battlefield tapped. If you control eight or more lands, repeat this process once.

Kraum, Ludevic's Opus

Flying, haste
Whenever an opponent casts their second spell each turn, draw a card.
Partner (You can have two commanders if both have partner.)

Detective of the Month

Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
As long as you have the city's blessing, Detectives you control can't be blocked.
Whenever you draw your second card each turn, create a 2/2 white and blue Detective creature token.

Saruman the White

Ward {2}
Whenever you cast your second spell each turn, amass Orcs 2. (Put two +1/+1 counters on an Army you control. It's also an Orc. If you don't control an Army, create a 0/0 black Orc Army creature token first.)

Faerie Vandal

Flash (You may cast this spell any time you could cast an instant.)
Flying
Whenever you draw your second card each turn, put a +1/+1 counter on Faerie Vandal.

Jaded Analyst

Defender
Whenever you draw your second card each turn, Jaded Analyst loses defender and gains vigilance until end of turn.

Elrond, Lord of Rivendell

Whenever Elrond, Lord of Rivendell or another creature you control enters, scry 1. If this is the second time this ability has resolved this turn, the Ring tempts you.

Raging Battle Mouse

The second spell you cast each turn costs {1} less to cast.
Celebration — At the beginning of combat on your turn, if two or more nonland permanents entered the battlefield under your control this turn, target creature you control gets +1/+1 until end of turn.

Tomb of Horrors Adventurer

When Tomb of Horrors Adventurer enters, you take the initiative.
Whenever you cast your second spell each turn, copy it. If you've completed a dungeon, copy that spell twice instead. You may choose new targets for the copies. (A copy of a permanent spell becomes a token.)

Mantle of Tides

Equipped creature gets +1/+2.
Whenever you draw your second card each turn, attach Mantle of Tides to target creature you control.
Equip {3} ({3}: Attach to target creature you control. Equip only as a sorcery.)

Saruman of Many Colors

Ward—Discard an enchantment, instant, or sorcery card.
Whenever you cast your second spell each turn, each opponent mills two cards. When one or more cards are milled this way, exile target enchantment, instant, or sorcery card with equal or lesser mana value than that spell from an opponent's graveyard. Copy the exiled card. You may cast the copy without paying its mana cost.

Jolrael, Mwonvuli Recluse

Whenever you draw your second card each turn, create a 2/2 green Cat creature token.
{4}{G}{G}: Until end of turn, creatures you control have base power and toughness X/X, where X is the number of cards in your hand.

Monologue Tax

Whenever an opponent casts their second spell each turn, you create a Treasure token.

Dogged Detective

When Dogged Detective enters, surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)
Whenever an opponent draws their second card each turn, you may return Dogged Detective from your graveyard to your hand.

Rammas Echor, Ancient Shield

Whenever you cast your second spell each turn, draw a card, then create a 0/3 white Wall creature token with defender.
At the beginning of combat on your turn, creatures you control with defender gain exalted until end of turn. (Whenever a creature you control attacks alone, it gets +1/+1 until end of turn for each instance of exalted among permanents you control.)

Loxodon Eavesdropper

When Loxodon Eavesdropper enters, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")
Whenever you draw your second card each turn, Loxodon Eavesdropper gets +1/+1 and gains vigilance until end of turn.

Improbable Alliance

Whenever you draw your second card each turn, create a 1/1 blue Faerie creature token with flying.
{4}{U}{R}: Draw a card, then discard a card.

Breeches, the Blastmaker

Menace
Whenever you cast your second spell each turn, you may sacrifice an artifact. If you do, flip a coin. When you win the flip, copy that spell. You may choose new targets for the copy. When you lose the flip, Breeches, the Blastmaker deals damage equal to that spell's mana value to any target.

Morska, Undersea Sleuth

You have no maximum hand size.
At the beginning of your upkeep, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")
Whenever you draw your second card each turn, put two +1/+1 counters on Morska, Undersea Sleuth.

Monk of the Open Hand

Flurry of Blows — Whenever you cast your second spell each turn, put a +1/+1 counter on Monk of the Open Hand.

Mystic Skyfish

Whenever you draw your second card each turn, Mystic Skyfish gains flying until end of turn.

Razzle-Dazzler

Whenever you cast your second spell each turn, put a +1/+1 counter on Razzle-Dazzler. It can't be blocked this turn.

Goldbug, Scrappy Scout

Living metal (During your turn, this Vehicle is also a creature.)
Human spells you control can't be countered.
Whenever Goldbug and at least one Human attack, draw a card and convert Goldbug.

Goldbug, Humanity's Ally

More Than Meets the Eye {W}{U} (You may cast this card converted for {W}{U}.)
Prevent all combat damage that would be dealt to attacking Humans you control.
Whenever you cast your second spell each turn, convert Goldbug.

Goldbug, Humanity's Ally // Goldbug, Scrappy Scout

Clarion Spirit

Whenever you cast your second spell each turn, create a 1/1 white Spirit creature token with flying.

Stalwarts of Osgiliath

When Stalwarts of Osgiliath enters, the Ring tempts you.
Whenever you draw your second card each turn, put a +1/+1 counter on Stalwarts of Osgiliath.

Jori En, Ruin Diver

Whenever you cast your second spell each turn, draw a card.

Steelgaze Griffin

Flying
Whenever you draw your second card each turn, Steelgaze Griffin gets +2/+0 until end of turn.

Gurgling Anointer

Flying
Whenever you draw your second card each turn, put a +1/+1 counter on Gurgling Anointer.
When Gurgling Anointer dies, return another target creature card with mana value less than or equal to Gurgling Anointer's power from your graveyard to the battlefield.

Shackle Slinger

Whenever you cast your second spell each turn, choose target creature an opponent controls. If it's tapped, put a stun counter on it. Otherwise, tap it. (If a permanent with a stun counter would become untapped, remove one from it instead.)

On the Trail

Whenever you draw your second card each turn, you may put a land card from your hand onto the battlefield tapped.

The Council of Four

Whenever a player draws their second card during their turn, you draw a card.
Whenever a player casts their second spell during their turn, you create a 2/2 white Knight creature token.

Howling Moon

At the beginning of combat on your turn, target Wolf or Werewolf you control gets +2/+2 until end of turn.
Whenever an opponent casts their second spell each turn, create a 2/2 green Wolf creature token.

Gixian Puppeteer

Whenever you draw your second card each turn, each opponent loses 2 life and you gain 2 life.
When Gixian Puppeteer dies, return another target creature card with mana value 3 or less from your graveyard to the battlefield.

Private Eye

Other Detectives you control get +1/+1.
Whenever you draw your second card each turn, target Detective can't be blocked this turn.

Lavinia, Foil to Conspiracy

Vigilance
Whenever you cast your second spell each turn, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")
{T}: Add {C}{C}. Activate only during an opponent's turn.

Mad Ratter

Whenever you draw your second card each turn, create two 1/1 black Rat creature tokens.

Eris, Roar of the Storm

This spell costs {2} less to cast for each different mana value among instant and sorcery cards in your graveyard.
Flying, prowess
Whenever you cast your second spell each turn, create a 4/4 red Dragon Elemental creature token with flying and prowess.

Thopter Mechanic

Whenever you draw your second card each turn, put a +1/+1 counter on Thopter Mechanic.
When Thopter Mechanic dies, create a 1/1 colorless Thopter artifact creature token with flying.

Stella Lee, Wild Card

Whenever you cast your second spell each turn, exile the top card of your library. Until the end of your next turn, you may play that card.
{T}: Copy target instant or sorcery spell you control. You may choose new targets for the copy. Activate only if you've cast three or more spells this turn.

Emrakul's Messenger

Devoid (This card has no color.)
Flying
Whenever you draw your second card each turn, create a 0/1 colorless Eldrazi Spawn creature token with "Sacrifice this creature: Add {C}."

Knights of Dol Amroth

Whenever you draw your second card each turn, put a +1/+1 counter on Knights of Dol Amroth.

Minn, Wily Illusionist

Whenever you draw your second card each turn, create a 1/1 blue Illusion creature token with "This creature gets +1/+0 for each other Illusion you control."
Whenever an Illusion you control dies, you may put a permanent card with mana value less than or equal to that creature's power from your hand onto the battlefield.

Thunder Drake

Flying
Whenever you cast your second spell each turn, put a +1/+1 counter on Thunder Drake.

Ledger Shredder

Flying
Whenever a player casts their second spell each turn, Ledger Shredder connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on this creature.)

Edgin, Larcenous Lutenist

Each nonland card in your hand without foretell has foretell. Its foretell cost is equal to its mana cost reduced by {2}. (During your turn, you may pay {2} and exile it from your hand face down. Cast it on a later turn for its foretell cost.)
Whenever you cast your second spell each turn, goad target creature an opponent controls.

Oji, the Exquisite Blade

When Oji, the Exquisite Blade enters, you gain 2 life and scry 2.
Whenever you cast your second spell each turn, exile up to one target creature you control, then return it to the battlefield under its owner's control.

Faerie Mastermind

Flash
Flying
Whenever an opponent draws their second card each turn, you draw a card.
{3}{U}: Each player draws a card.

Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Bloodsky Berserker

Whenever you cast your second spell each turn, put two +1/+1 counters on Bloodsky Berserker. It gains menace until end of turn. (It can't be blocked except by two or more creatures.)

Gavi, Nest Warden

You may pay {0} rather than pay the cycling cost of the first card you cycle each turn.
Whenever you draw your second card each turn, create a 2/2 red and white Dinosaur Cat creature token.

Trouble in Pairs

If an opponent would begin an extra turn, that player skips that turn instead.
Whenever an opponent attacks you with two or more creatures, draws their second card each turn, or casts their second spell each turn, you draw a card.

Jace, Arcane Strategist

Whenever you draw your second card each turn, put a +1/+1 counter on target creature you control.
+1: Draw a card.
−7: Creatures you control can't be blocked this turn.

Iron-Fist Pulverizer

Reach
Whenever you cast your second spell each turn, Iron-Fist Pulverizer deals 2 damage to target opponent. Scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Prince Imrahil the Fair

Whenever you draw your second card each turn, create a 1/1 white Human Soldier creature token.

Codespell Cleric

Vigilance
When Codespell Cleric enters, if it was the second spell you cast this turn, put a +1/+1 counter on target creature.

Irencrag Pyromancer

Whenever you draw your second card each turn, Irencrag Pyromancer deals 3 damage to any target.

Infernal Pet

Whenever you cast your second spell each turn, put a +1/+1 counter on Infernal Pet and it gains flying until end of turn.

Storm of Saruman

Ward {3}
Whenever you cast your second spell each turn, copy it, except the copy isn't legendary. You may choose new targets for the copy. (A copy of a permanent spell becomes a token.)

Mangara, the Diplomat

Lifelink
Whenever an opponent attacks with creatures, if two or more of those creatures are attacking you and/or planeswalkers you control, draw a card.
Whenever an opponent casts their second spell each turn, draw a card.

Ian Malcolm, Chaotician

Whenever a player draws their second card each turn, that player exiles the top card of their library.
During each player's turn, that player may cast a spell from among the cards they don't own exiled with Ian Malcolm, Chaotician, and mana of any type can be spent to cast it.

Ethereal Investigator

Flying
When Ethereal Investigator enters, investigate X times, where X is the number of opponents you have. (To investigate, create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")
Whenever you draw your second card each turn, create a 1/1 white Spirit creature token with flying.

Ashling, Flame Dancer

You don't lose unspent red mana as steps and phases end.
Magecraft — Whenever you cast or copy an instant or sorcery spell, discard a card, then draw a card. If this is the second time this ability has resolved this turn, Ashling, Flame Dancer deals 2 damage to each opponent and each creature they control. If it's the third time, add {R}{R}{R}{R}.

Kraum, Violent Cacophony

Flying
Whenever you cast your second spell each turn, put a +1/+1 counter on Kraum, Violent Cacophony and draw a card.

Malcolm, the Eyes

Flying, haste
Whenever you cast your second spell each turn, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

Doomskar Oracle

Whenever you cast your second spell each turn, you gain 2 life.
Foretell {W} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Monk Class

(Gain the next level as a sorcery to add its ability.)
The second spell you cast each turn costs {1} less to cast.
{W}{U}: Level 2
When this Class becomes level 2, return up to one target nonland permanent to its owner's hand.
{1}{W}{U}: Level 3
At the beginning of your upkeep, exile the top card of your library. For as long as it remains exiled, it has "You may cast this card from exile as long as you've cast another spell this turn."

Elmar, Ulvenwald Informant

Haste
Whenever you cast your second spell each turn, untap target creature, then investigate. (Create a colorless Clue artifact token with "{2}, Sacrifice this artifact: Draw a card.")
Friends forever (You can have two commanders if both have friends forever.)

Pyromancer's Assault

Whenever you cast your second spell each turn, Pyromancer's Assault deals 2 damage to any target.

Incursion Specialist

Whenever you cast your second spell each turn, Incursion Specialist gets +2/+0 until end of turn and can't be blocked this turn.

Brimstone Roundup

Whenever you cast your second spell each turn, create a 1/1 red Mercenary creature token with "{T}: Target creature you control gets +1/+0 until end of turn. Activate only as a sorcery."
Plot {2}{R} (You may pay {2}{R} and exile this card from your hand. Cast it as a sorcery on a later turn without paying its mana cost. Plot only as a sorcery.)

Firja, Judge of Valor

Flying, lifelink
Whenever you cast your second spell each turn, look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.

Bloodhaze Wolverine

Whenever you draw your second card each turn, Bloodhaze Wolverine gets +1/+1 and gains first strike until end of turn.

Lat-Nam Adept

Whenever you draw your second card each turn, put a +1/+1 counter on Lat-Nam Adept.