Akroma's Vengeance

Destroy all artifacts, creatures, and enchantments.
Cycling {3} ({3}, Discard this card: Draw a card.)

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Blood Money

Destroy all creatures. For each nontoken creature destroyed this way, you create a tapped Treasure token.

Blood on the Snow

Choose one —
• Destroy all creatures.
• Destroy all planeswalkers.
Then return a creature or planeswalker card with mana value X or less from your graveyard to the battlefield, where X is the amount of {S} spent to cast this spell. ({S} is mana from a snow source.)

Blot Out the Sky

Create X tapped 2/1 white and black Inkling creature tokens with flying. If X is 6 or more, destroy all noncreature, nonland permanents.

Bontu's Last Reckoning

Destroy all creatures. Lands you control don't untap during your next untap step.

Catastrophe

Destroy all lands or all creatures. Creatures destroyed this way can't be regenerated.

Citywide Bust

Destroy all creatures with toughness 4 or greater.

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Crisis of Conscience

Choose one —
• Destroy all tokens.
• Destroy all nonland, nontoken permanents.

Crux of Fate

Choose one —
• Destroy all Dragon creatures.
• Destroy all non-Dragon creatures.

Damnation

Destroy all creatures. They can't be regenerated.

Damning Verdict

Destroy all creatures with no counters on them.

Day of Judgment

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Deathbringer Regent

Flying
When Deathbringer Regent enters, if you cast it from your hand and there are five or more other creatures on the battlefield, destroy all other creatures.

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle Decree of Pain, all creatures get -2/-2 until end of turn.

Depopulate

Each player who controls a multicolored creature draws a card. Then destroy all creatures.

Devastating Mastery

You may pay {2}{W}{W} rather than pay this spell's mana cost.
If the {2}{W}{W} cost was paid, an opponent chooses up to two nonland permanents they control and returns them to their owner's hand.
Destroy all nonland permanents.

Don't Move

Destroy all tapped creatures. Until your next turn, whenever a creature becomes tapped, destroy it.

End Hostilities

Destroy all creatures and all permanents attached to creatures.

Doomskar

Destroy all creatures.
Foretell {1}{W}{W} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Dawn

Aftermath (Cast this spell only from your graveyard. Then exile it.)
Return all creature cards with power 2 or less from your graveyard to your hand.

Dusk

Destroy all creatures with power 3 or greater.

Dusk // Dawn

Elspeth, Sun's Champion

+1: Create three 1/1 white Soldier creature tokens.
−3: Destroy all creatures with power 4 or greater.
−7: You get an emblem with "Creatures you control get +2/+2 and have flying."

Expel the Interlopers

Choose a number between 0 and 10. Destroy all creatures with power greater than or equal to the chosen number.

Exterminatus

Nonland permanents your opponents control lose indestructible until end of turn.
Destroy all nonland permanents.

Extinguish All Hope

Extinction

Destroy all creatures of the creature type of your choice.

Final Showdown

Spree (Choose one or more additional costs.)
+ {1} — All creatures lose all abilities until end of turn.
+ {1} — Choose a creature you control. It gains indestructible until end of turn.
+ {3}{W}{W} — Destroy all creatures.

Final Act

Choose one or more —
• Destroy all creatures.
• Destroy all planeswalkers.
• Destroy all battles.
• Exile all graveyards.
• Each opponent loses all counters.

Fell the Mighty

Destroy all creatures with power greater than target creature's power.

Fated Retribution

Destroy all creatures and planeswalkers. If it's your turn, scry 2.

Fortunate Few

Choose a nonland permanent you don't control, then each other player chooses a nonland permanent they don't control that hasn't been chosen this way. Destroy all other nonland permanents.

Guan Yu's 1,000-Li March

Hellfire

Destroy all nonblack creatures. Hellfire deals X plus 3 damage to you, where X is the number of creatures that died this way.

Hour of Revelation

This spell costs {3} less to cast if there are ten or more nonland permanents on the battlefield.
Destroy all nonland permanents.

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Marchesa, Resolute Monarch

Menace, deathtouch
Whenever Marchesa, Resolute Monarch attacks, remove all counters from up to one target permanent.
At the beginning of your upkeep, if you haven't been dealt combat damage since your last turn, you draw a card and you lose 1 life.

Invasion of Fiora

(As a Siege enters, choose an opponent to protect it. You and others can attack it. When it's defeated, exile it, then cast it transformed.)
When Invasion of Fiora enters, choose one or both —
• Destroy all legendary creatures.
• Destroy all nonlegendary creatures.

Invasion of Fiora // Marchesa, Resolute Monarch

Jokulhaups

Destroy all artifacts, creatures, and lands. They can't be regenerated.

Kindred Dominance

Choose a creature type. Destroy all creatures that aren't of the chosen type.

Kirtar's Wrath

Destroy all creatures. They can't be regenerated.
Threshold — If seven or more cards are in your graveyard, instead destroy all creatures, then create two 1/1 white Spirit creature tokens with flying. Creatures destroyed this way can't be regenerated.

Life's Finale

Destroy all creatures, then search target opponent's library for up to three creature cards and put them into their graveyard. Then that player shuffles.

Mageta the Lion

{2}{W}{W}, {T}, Discard two cards: Destroy all creatures except for Mageta the Lion. Those creatures can't be regenerated.

March of Souls

Destroy all creatures. They can't be regenerated. For each creature destroyed this way, its controller creates a 1/1 white Spirit creature token with flying.

Magus of the Disk

Magus of the Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Mandate of Abaddon

Choose target creature you control. Destroy all creatures with power less than that creature's power.

Martial Coup

Create X 1/1 white Soldier creature tokens. If X is 5 or more, destroy all other creatures.

Mass Calcify

Myojin of Cleansing Fire

Myojin of Cleansing Fire enters with a divinity counter on it if you cast it from your hand.
Myojin of Cleansing Fire has indestructible as long as it has a divinity counter on it.
Remove a divinity counter from Myojin of Cleansing Fire: Destroy all other creatures.

Necromantic Selection

Destroy all creatures, then return a creature card put into a graveyard this way to the battlefield under your control. It's a black Zombie in addition to its other colors and types. Exile Necromantic Selection.

Nevinyrral's Disk

Nevinyrral's Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Nevinyrral, Urborg Tyrant

Hexproof from artifacts, creatures, and enchantments
When Nevinyrral, Urborg Tyrant enters, create a tapped 2/2 black Zombie creature token for each creature that died this turn.
When Nevinyrral dies, you may pay {1}. When you do, destroy all artifacts, creatures, and enchantments.

Novablast Wurm

Whenever Novablast Wurm attacks, destroy all other creatures.

Obliterate

This spell can't be countered.
Destroy all artifacts, creatures, and lands. They can't be regenerated.

Ondu Skyruins

Ondu Skyruins enters tapped.
{T}: Add {W}.

Ondu Inversion

Ondu Inversion // Ondu Skyruins

One Ring to Rule Them All

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — The Ring tempts you, then each player mills cards equal to your Ring-bearer's power.
II — Destroy all nonlegendary creatures.
III — Each opponent loses 1 life for each creature card in that player's graveyard.

Path of Peril

Cleave {4}{W}{B} (You may cast this spell for its cleave cost. If you do, remove the words in square brackets.)
Destroy all creatures [with mana value 2 or less].

Pest Control

Destroy all nonland permanents with mana value 1 or less.
Cycling {2} ({2}, Discard this card: Draw a card.)

Phyrexian Rebirth

Destroy all creatures, then create an X/X colorless Phyrexian Horror artifact creature token, where X is the number of creatures destroyed this way.

Phyrexian Scriptures

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Put a +1/+1 counter on up to one target creature. That creature becomes an artifact in addition to its other types.
II — Destroy all nonartifact creatures.
III — Exile all opponents' graveyards.

Plague Wind

Destroy all creatures you don't control. They can't be regenerated.

Planar Cleansing

Planar Outburst

Destroy all nonland creatures.
Awaken 4—{5}{W}{W}{W} (If you cast this spell for {5}{W}{W}{W}, also put four +1/+1 counters on target land you control and it becomes a 0/0 Elemental creature with haste. It's still a land.)

Retribution of the Meek

Destroy all creatures with power 4 or greater. They can't be regenerated.

Ritual of Soot

Destroy all creatures with mana value 3 or less.

Rout

You may cast Rout as though it had flash if you pay {2} more to cast it. (You may cast it any time you could cast an instant.)
Destroy all creatures. They can't be regenerated.

Ruinous Ultimatum

Destroy all nonland permanents your opponents control.

Shatter the Sky

Each player who controls a creature with power 4 or greater draws a card. Then destroy all creatures.

Slash the Ranks

Destroy all creatures and planeswalkers except for commanders.

Solar Tide

Choose one —
• Destroy all creatures with power 2 or less.
• Destroy all creatures with power 3 or greater.
Entwine—Sacrifice two lands. (Choose both if you pay the entwine cost.)

Soulscour

Sunblast Angel

Flying
When Sunblast Angel enters, destroy all tapped creatures.

Sunscour

You may exile two white cards from your hand rather than pay this spell's mana cost.
Destroy all creatures.

Structural Assault

Destroy all artifacts, then Structural Assault deals damage to each creature equal to the number of artifacts that were put into graveyards from the battlefield this turn.

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

The Battle of Bywater

Destroy all creatures with power 3 or greater. Then create a Food token for each creature you control. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")

Their Name Is Death

The Night of the Doctor

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after II.)
I — Destroy all creatures.
II — Return target legendary creature card from your graveyard to the battlefield. Put your choice of a first strike, vigilance, or lifelink counter on it.

The Nipton Lottery

Choose a creature at random. You gain control of that creature until end of turn. Untap it. It gains haste until end of turn. Then destroy all other creatures.

Time Wipe

Return a creature you control to its owner's hand, then destroy all creatures.

Urza's Sylex

{2}{W}{W}, {T}, Exile Urza's Sylex: Each player chooses six lands they control. Destroy all other permanents. Activate only as a sorcery.
When Urza's Sylex is put into exile from the battlefield, you may pay {2}. If you do, search your library for a planeswalker card, reveal it, put it into your hand, then shuffle.

Sandswirl Wanderglyph

Flying
Whenever an opponent casts a spell during their turn, they can't attack you or planeswalkers you control this turn.
Each opponent who attacked you or a planeswalker you control this turn can't cast spells.

Unstable Glyphbridge

When Unstable Glyphbridge enters, if you cast it, for each player, choose a creature with power 2 or less that player controls. Then destroy all creatures except creatures chosen this way.
Craft with artifact {3}{W}{W} ({3}{W}{W}, Exile this artifact, Exile another artifact you control or an artifact card from your graveyard: Return this card transformed under its owner's control. Craft only as a sorcery.)

Unstable Glyphbridge // Sandswirl Wanderglyph

Vanquish the Horde

This spell costs {1} less to cast for each creature on the battlefield.
Destroy all creatures.

Wakening Sun's Avatar

When Wakening Sun's Avatar enters, if you cast it from your hand, destroy all non-Dinosaur creatures.

White Sun's Twilight

You gain X life. Create X 1/1 colorless Phyrexian Mite artifact creature tokens with toxic 1 and "This creature can't block." If X is 5 or more, destroy all other creatures. (Players dealt combat damage by a creature with toxic 1 also get a poison counter.)

Winds of Rath

Destroy all creatures that aren't enchanted. They can't be regenerated.

Wrath of God

Aether Snap

Remove all counters from all permanents and exile all tokens.

Angel of the Dire Hour

Flash
Flying
When Angel of the Dire Hour enters, if you cast it from your hand, exile all attacking creatures.

Descend upon the Sinful

Exile all creatures.
Delirium — Create a 4/4 white Angel creature token with flying if there are four or more card types among cards in your graveyard.

Dimensional Breach

Exile all permanents. For as long as any of those cards remain exiled, at the beginning of each player's upkeep, that player returns one of the exiled cards they own to the battlefield.

Everything Comes to Dust

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Exile all creatures except those that share a creature type with a creature that convoked this spell, all artifacts, and all enchantments.

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Final Judgment

Oversimplify

Exile all creatures. Each player creates a 0/0 green and blue Fractal creature token and puts a number of +1/+1 counters on it equal to the total power of creatures they controlled that were exiled this way.

Play of the Game

Assist (Another player can pay up to {6} of this spell's cost.)
Exile all nonland permanents.

Settle the Wreckage

Exile all attacking creatures target player controls. That player may search their library for that many basic land cards, put those cards onto the battlefield tapped, then shuffle.

Shadows' Verdict

Exile all creatures and planeswalkers with mana value 3 or less from the battlefield and all creature and planeswalker cards with mana value 3 or less from all graveyards.

Sunfall

Exile all creatures. Incubate X, where X is the number of creatures exiled this way. (Create an Incubator token with X +1/+1 counters on it and "{2}: Transform this artifact." It transforms into a 0/0 Phyrexian artifact creature.)

Urza's Ruinous Blast

(You may cast a legendary sorcery only if you control a legendary creature or planeswalker.)
Exile all nonland permanents that aren't legendary.