Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Isolation Cell

Whenever an opponent casts a creature spell, that player loses 2 life unless they pay {2}.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Karlov of the Ghost Council

Whenever you gain life, put two +1/+1 counters on Karlov of the Ghost Council.
{W}{B}, Remove six +1/+1 counters from Karlov of the Ghost Council: Exile target creature.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Authority of the Consuls

Creatures your opponents control enter the battlefield tapped.
Whenever a creature enters the battlefield under an opponent's control, you gain 1 life.

Tomik, Distinguished Advokist

Flying
Lands on the battlefield and land cards in graveyards can't be the targets of spells or abilities your opponents control.
Your opponents can't play land cards from graveyards.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Suture Priest

Whenever another creature enters the battlefield under your control, you may gain 1 life.
Whenever a creature enters the battlefield under an opponent's control, you may have that player lose 1 life.

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Dawn

Aftermath (Cast this spell only from your graveyard. Then exile it.)
Return all creature cards with power 2 or less from your graveyard to your hand.

Dusk

Destroy all creatures with power 3 or greater.

Dusk // Dawn

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Bojuka Bog

Bojuka Bog enters the battlefield tapped.
When Bojuka Bog enters the battlefield, exile target player's graveyard.
{T}: Add {B}.

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

Evra, Halcyon Witness

Lifelink
{4}: Exchange your life total with Evra, Halcyon Witness's power.

Sorin, Solemn Visitor

+1: Until your next turn, creatures you control get +1/+0 and gain lifelink.
−2: Create a 2/2 black Vampire creature token with flying.
−6: You get an emblem with "At the beginning of each opponent's upkeep, that player sacrifices a creature."

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Tithe Drinker

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Norn's Annex

({W/P} can be paid with either {W} or 2 life.)
Creatures can't attack you or planeswalkers you control unless their controller pays {W/P} for each of those creatures.

Swamp

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Aura of Silence

Artifact and enchantment spells your opponents cast cost {2} more to cast.
Sacrifice Aura of Silence: Destroy target artifact or enchantment.

Windborn Muse

Flying
Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Polluted Bonds

Whenever a land enters the battlefield under an opponent's control, that player loses 2 life and you gain 2 life.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter the battlefield tapped.

Aven Mindcensor

Flash
Flying
If an opponent would search a library, that player searches the top four cards of that library instead.

Sol Ring

Land Tax

At the beginning of your upkeep, if an opponent controls more lands than you, you may search your library for up to three basic land cards, reveal them, put them into your hand, then shuffle.

Crested Sunmare

Other Horses you control have indestructible.
At the beginning of each end step, if you gained life this turn, create a 5/5 white Horse creature token.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Ashes of the Abhorrent

Players can't cast spells from graveyards or activate abilities of cards in graveyards.
Whenever a creature dies, you gain 1 life.

Pristine Talisman

Spelltithe Enforcer

Whenever an opponent casts a spell, that player sacrifices a permanent unless they pay {1}.

Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Soul's Attendant

Whenever another creature enters the battlefield, you may gain 1 life.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Nevinyrral's Disk

Nevinyrral's Disk enters the battlefield tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Leonin Arbiter

Players can't search libraries. Any player may pay {2} for that player to ignore this effect until end of turn.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Temple of Silence

Temple of Silence enters the battlefield tapped.
When Temple of Silence enters the battlefield, scry 1.
{T}: Add {W} or {B}.

Thalia, Guardian of Thraben

First strike
Noncreature spells cost {1} more to cast.

Soul Warden

Whenever another creature enters the battlefield, you gain 1 life.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Kokusho, the Evening Star

Flying
When Kokusho, the Evening Star dies, each opponent loses 5 life. You gain life equal to the life lost this way.

Plains

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Orzhov Signet

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. Caves of Koilos deals 1 damage to you.

Tocatli Honor Guard

Creatures entering the battlefield don't cause abilities to trigger.

Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Thran Dynamo

Thalia, Heretic Cathar

First strike
Creatures and nonbasic lands your opponents control enter the battlefield tapped.

Disenchant

Cabal Stronghold

{T}: Add {C}.
{3}, {T}: Add {B} for each basic Swamp you control.

Open the Vaults

Return all artifact and enchantment cards from all graveyards to the battlefield under their owners' control. (Auras with nothing to enchant remain in graveyards.)

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Blood Seeker

Whenever a creature enters the battlefield under an opponent's control, you may have that player lose 1 life.

No Mercy

Whenever a creature deals damage to you, destroy it.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Righteous Aura

{W}, Pay 2 life: The next time a source of your choice would deal damage to you this turn, prevent that damage.

Silent Clearing

{T}, Pay 1 life: Add {W} or {B}.
{1}, {T}, Sacrifice Silent Clearing: Draw a card.

Angelic Accord

At the beginning of each end step, if you gained 4 or more life this turn, create a 4/4 white Angel creature token with flying.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent or discards a card.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters the battlefield, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Archangel of Tithes

Flying
As long as Archangel of Tithes is untapped, creatures can't attack you or planeswalkers you control unless their controller pays {1} for each of those creatures.
As long as Archangel of Tithes is attacking, creatures can't block unless their controller pays {1} for each of those creatures.

Greed

Forsake the Worldly

Exile target artifact or enchantment.
Cycling {2} ({2}, Discard this card: Draw a card.)