Phyrexian Obliterator

Trample
Whenever a source deals damage to Phyrexian Obliterator, that source's controller sacrifices that many permanents of their choice.

Tormented Hero

Tormented Hero enters tapped.
Heroic — Whenever you cast a spell that targets Tormented Hero, each opponent loses 1 life. You gain life equal to the life lost this way.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Thrull Parasite

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
{T}, Pay 2 life: Remove a counter from target nonland permanent.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Imperial Seal

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Zhentarim Bandit

Whenever Zhentarim Bandit attacks, you may pay 1 life. If you do, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Temporal Extortion

When you cast this spell, any player may pay half their life, rounded up. If a player does, counter Temporal Extortion.
Take an extra turn after this one.

Navigator's Compass

When Navigator's Compass enters, you gain 3 life.
{T}: Until end of turn, target land you control becomes the basic land type of your choice in addition to its other types.

Teferi's Puzzle Box

At the beginning of each player's draw step, that player puts the cards in their hand on the bottom of their library in any order, then draws that many cards.

Volrath's Dungeon

Pay 5 life: Destroy Volrath's Dungeon. Any player may activate this ability but only during their turn.
Discard a card: Target player puts a card from their hand on top of their library. Activate only as a sorcery.

Demon's Horn

Whenever a player casts a black spell, you may gain 1 life.

Moriok Replica

{1}{B}, Sacrifice Moriok Replica: You draw two cards and you lose 2 life.

Ob Nixilis Reignited

+1: You draw a card and you lose 1 life.
−3: Destroy target creature.
−8: Target opponent gets an emblem with "Whenever a player draws a card, you lose 2 life."

Master of the Feast

Flying
At the beginning of your upkeep, each opponent draws a card.

Undercity's Embrace

Target opponent sacrifices a creature of their choice. If you control a creature with power 4 or greater, you gain 4 life.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Fatal Lore

An opponent chooses one —
• You draw three cards.
• You destroy up to two target creatures that player controls. They can't be regenerated. That player draws up to three cards.

Eye of Vecna

When Eye of Vecna enters, you draw a card and you lose 2 life.
At the beginning of your upkeep, you may pay {2}. If you do, you draw a card and you lose 2 life.

Mire Triton

Deathtouch
When Mire Triton enters, mill two cards and you gain 2 life. (To mill a card, put the top card of your library into your graveyard.)

Lotus Bloom

Suspend 3—{0} (Rather than cast this card from your hand, pay {0} and exile it with three time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
{T}, Sacrifice Lotus Bloom: Add three mana of any one color.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Font of Mythos

At the beginning of each player's draw step, that player draws two additional cards.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Darksteel Plate

Indestructible
Equipped creature has indestructible.
Equip {2}

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Howling Mine

At the beginning of each player's draw step, if Howling Mine is untapped, that player draws an additional card.

Sol Ring

Golem's Heart

Whenever a player casts an artifact spell, you may gain 1 life.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Vampiric Tutor

Umbilicus

At the beginning of each player's upkeep, that player may pay 2 life. If they don't, they return a permanent they control to its owner's hand.

Damnable Pact

Target player draws X cards and loses X life.

Hedron Archive

{T}: Add {C}{C}.
{2}, {T}, Sacrifice this artifact: Draw two cards.

Crypt Incursion

Exile all creature cards from target player's graveyard. You gain 3 life for each card exiled this way.

Contagion

You may pay 1 life and exile a black card from your hand rather than pay this spell's mana cost.
Distribute two -2/-1 counters among one or two target creatures.

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis, the Hate-Twisted deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Swamp

Nightmare's Thirst

You gain 1 life. Target creature gets -X/-X until end of turn, where X is the amount of life you gained this turn.

Serrated Scorpion

When Serrated Scorpion dies, it deals 2 damage to each opponent and you gain 2 life.

Patchwork Gnomes

Discard a card: Regenerate Patchwork Gnomes. (The next time this creature would be destroyed this turn, instead tap it, remove it from combat, and heal all damage on it.)

Commander's Plate

Equipped creature gets +3/+3 and has protection from each color that's not in your commander's color identity.
Equip commander {3}
Equip {5}

Jet Medallion

Black spells you cast cost {1} less to cast.

Scroll of Avacyn

{1}, Sacrifice Scroll of Avacyn: Draw a card. If you control an Angel, you gain 5 life.

Withering Boon

As an additional cost to cast this spell, pay 3 life.
Counter target creature spell.

Elsewhere Flask

When Elsewhere Flask enters, draw a card.
Sacrifice Elsewhere Flask: Choose a basic land type. Each land you control becomes that type until end of turn.

Diamond Mare

As Diamond Mare enters, choose a color.
Whenever you cast a spell of the chosen color, you gain 1 life.

Ivory Crane Netsuke

At the beginning of your upkeep, if you have seven or more cards in hand, you gain 4 life.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Feed the Infection

You draw three cards and you lose 3 life.
Corrupted — Each opponent who has three or more poison counters loses 3 life.

Dark Ritual

Oona's Prowler

Flying
Discard a card: Oona's Prowler gets -2/-0 until end of turn. Any player may activate this ability.

Olivia's Dragoon

Discard a card: Olivia's Dragoon gains flying until end of turn.

Pharika's Cure

Pharika's Cure deals 2 damage to target creature and you gain 2 life.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Prism Ring

As Prism Ring enters, choose a color.
Whenever you cast a spell of the chosen color, you gain 1 life.

Hoarder's Greed

You lose 2 life and draw two cards, then clash with an opponent. If you win, repeat this process. (Each clashing player reveals the top card of their library, then puts that card on the top or bottom. A player wins if their card had a higher mana value.)

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Bubbling Muck

Until end of turn, whenever a player taps a Swamp for mana, that player adds an additional {B}.

Scroll Rack

{1}, {T}: Exile any number of cards from your hand face down. Put that many cards from the top of your library into your hand. Then look at the exiled cards and put them on top of your library in any order.

Sovereign's Bite

Target player loses 3 life and you gain 3 life.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Cabal Initiate

Discard a card: Cabal Initiate gains lifelink until end of turn.
Threshold — Cabal Initiate gets +1/+2 as long as seven or more cards are in your graveyard.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Syphon Soul

Syphon Soul deals 2 damage to each other player. You gain life equal to the damage dealt this way.

Ambition's Cost

You draw three cards and you lose 3 life.

Feast of Flesh

Feast of Flesh deals X damage to target creature and you gain X life, where X is 1 plus the number of cards named Feast of Flesh in all graveyards.

Foreboding Fruit

Target player draws two cards and loses 2 life.
Adamant — If at least three black mana was spent to cast this spell, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")

Elixir of Immortality

{2}, {T}: You gain 5 life. Shuffle Elixir of Immortality and your graveyard into their owner's library.

Golden Egg

When Golden Egg enters, draw a card.
{1}, {T}, Sacrifice Golden Egg: Add one mana of any color.
{2}, {T}, Sacrifice Golden Egg: You gain 3 life.

Last Caress

Target player loses 1 life and you gain 1 life.
Draw a card.

Reliquary Tower

Harrowing Journey

Target player draws three cards and loses 3 life.

Nykthos, Shrine to Nyx

{T}: Add {C}.
{2}, {T}: Choose a color. Add an amount of mana of that color equal to your devotion to that color. (Your devotion to a color is the number of mana symbols of that color in the mana costs of permanents you control.)

Umezawa's Charm

Choose one —
• Target creature gets +2/+2 until end of turn.
• Target creature gets -1/-1 until end of turn.
• You gain 2 life.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Sceptre of Eternal Glory

{T}: Add one mana of any color.
{T}: Add three mana of any one color. Activate only if you control three or more lands with the same name.

Spellbook

Dusk Legion Zealot

When Dusk Legion Zealot enters, you draw a card and you lose 1 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Skirge Familiar

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Insatiable Avarice

Spree (Choose one or more additional costs.)
+ {2} — Search your library for a card, then shuffle and put that card on top.
+ {B}{B} — Target player draws three cards and loses 3 life.

Alms of the Vein

Target opponent loses 3 life and you gain 3 life.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Vampire's Kiss

Target player loses 2 life and you gain 2 life. Create two Blood tokens. (They're artifacts with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")

Baleful Mastery

You may pay {1}{B} rather than pay this spell's mana cost.
If the {1}{B} cost was paid, an opponent draws a card.
Exile target creature or planeswalker.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Profane Tutor

Suspend 2—{1}{B} (Rather than cast this card from your hand, pay {1}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search your library for a card, put that card into your hand, then shuffle.

Sensei's Divining Top

{1}: Look at the top three cards of your library, then put them back in any order.
{T}: Draw a card, then put Sensei's Divining Top on top of its owner's library.

Shamble Back

Exile target creature card from a graveyard. Create a 2/2 black Zombie creature token. You gain 2 life.

Blood Pact

Target player draws two cards and loses 2 life.

Nezumi Road Captain

Menace
Vehicles you control have menace. (They can't be blocked except by two or more creatures.)

Okiba Reckoner Raid

(As this Saga enters and after your draw step, add a lore counter.)
I, II — Each opponent loses 1 life and you gain 1 life.
III — Exile this Saga, then return it to the battlefield transformed under your control.

Okiba Reckoner Raid // Nezumi Road Captain

Night's Whisper

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Putrid Imp

Discard a card: Putrid Imp gains flying until end of turn.
Threshold — As long as seven or more cards are in your graveyard, Putrid Imp gets +1/+1 and can't block.

Shadowfeed

Exile target card from a graveyard. You gain 3 life.

Ulamog, the Infinite Gyre

When you cast this spell, destroy target permanent.
Indestructible
Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents of their choice.)
When Ulamog, the Infinite Gyre is put into a graveyard from anywhere, its owner shuffles their graveyard into their library.