Consider

Surveil 1. (Look at the top card of your library. You may put it into your graveyard.)
Draw a card.

Cooperate

Aftermath (Cast this spell only from your graveyard. Then exile it.)
Copy target instant or sorcery spell. You may choose new targets for the copy.

Refuse

Refuse deals damage to target spell's controller equal to that spell's mana value.

Refuse // Cooperate

Izzet Charm

Choose one —
• Counter target noncreature spell unless its controller pays {2}.
• Izzet Charm deals 2 damage to target creature.
• Draw two cards, then discard two cards.

Slick Sequence

Slick Sequence deals 2 damage to any target. If you've cast another spell this turn, draw a card.

Experimental Overload

Create an X/X blue and red Weird creature token, where X is the number of instant and sorcery cards in your graveyard. Then you may return an instant or sorcery card from your graveyard to your hand. Exile Experimental Overload.

Serum Visions

Invoke the Firemind

Choose one —
• Draw X cards.
• Invoke the Firemind deals X damage to any target.

Culmination of Studies

Exile the top X cards of your library. For each land card exiled this way, create a Treasure token. For each blue card exiled this way, draw a card. For each red card exiled this way, Culmination of Studies deals 1 damage to each opponent.

Beacon Bolt

Beacon Bolt deals damage to target creature equal to the total number of instant and sorcery cards you own in exile and in your graveyard.
Jump-start (You may cast this card from your graveyard by discarding a card in addition to paying its other costs. Then exile this card.)

Reinterpret

Counter target spell. You may cast a spell with an equal or lesser mana value from your hand without paying its mana cost.

Stitch in Time

Flip a coin. If you win the flip, take an extra turn after this one.

Schismotivate

Target creature gets +4/+0 until end of turn. Another target creature gets -4/-0 until end of turn.

Corporeal Projection

Target creature you control gains myriad until end of turn. (Whenever it attacks, for each opponent other than defending player, you may create a token that's a copy of that creature that's tapped and attacking that player or a planeswalker they control. Exile the tokens at end of combat.)
Overload {3}{U}{U}{R}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Epic Experiment

Exile the top X cards of your library. You may cast instant and sorcery spells with mana value X or less from among them without paying their mana costs. Then put all cards exiled this way that weren't cast into your graveyard.

Portent

Look at the top three cards of target player's library, then put them back in any order. You may have that player shuffle.
Draw a card at the beginning of the next turn's upkeep.

Lilah, Undefeated Slickshot

Prowess (Whenever you cast a noncreature spell, this creature gets +1/+1 until end of turn.)
Whenever you cast a multicolored instant or sorcery spell from your hand, exile that spell instead of putting it into your graveyard as it resolves. If you do, it becomes plotted. (You may cast it as a sorcery on a later turn without paying its mana cost.)

Inside Out

Switch target creature's power and toughness until end of turn.
Draw a card.

Inevitable Betrayal

Suspend 3—{1}{U}{U} (Rather than cast this card from your hand, pay {1}{U}{U} and exile it with three time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search target opponent's library for a creature card and put that card onto the battlefield under your control. Then that player shuffles.

Hypothesizzle

Draw two cards. Then you may discard a nonland card. When you do, Hypothesizzle deals 4 damage to target creature.

Ill-Timed Explosion

Draw two cards. Then you may discard two cards. When you do, Ill-Timed Explosion deals X damage to each creature, where X is the greatest mana value among cards discarded this way.

Prismari Command

Choose two —
• Prismari Command deals 2 damage to any target.
• Target player draws two cards, then discards two cards.
• Target player creates a Treasure token.
• Destroy target artifact.

Practical Research

Draw four cards. Then discard two cards unless you discard an instant or sorcery card.

Hard Evidence

Create a 0/3 blue Crab creature token.
Investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

Squee's Revenge

Choose a number. Flip a coin that many times or until you lose a flip, whichever comes first. If you win all the flips, draw two cards for each flip.

Expressive Iteration

Look at the top three cards of your library. Put one of them into your hand, put one of them on the bottom of your library, and exile one of them. You may play the exiled card this turn.

Teleportal

Target creature you control gets +1/+0 until end of turn and can't be blocked this turn.
Overload {3}{U}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Invade the City

Amass Zombies X, where X is the number of instant and sorcery cards in your graveyard. (Put X +1/+1 counters on an Army you control. It's also a Zombie. If you don't control an Army, create a 0/0 black Zombie Army creature token first.)

Preordain

Scry 2, then draw a card. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Cerebral Vortex

Target player draws two cards, then Cerebral Vortex deals damage to that player equal to the number of cards they've drawn this turn.

Gitaxian Probe

({U/P} can be paid with either {U} or 2 life.)
Look at target player's hand.
Draw a card.

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Ponder

Look at the top three cards of your library, then put them back in any order. You may shuffle.
Draw a card.

Galvanic Iteration

When you next cast an instant or sorcery spell this turn, copy that spell. You may choose new targets for the copy.
Flashback {1}{U}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Teach by Example

When you next cast an instant or sorcery spell this turn, copy that spell. You may choose new targets for the copy.

Multiple Choice

If X is 1, scry 1, then draw a card.
If X is 2, you may choose a player. They return a creature they control to its owner's hand.
If X is 3, create a 4/4 blue and red Elemental creature token.
If X is 4 or more, do all of the above.

Electrolyze

Electrolyze deals 2 damage divided as you choose among one or two targets.
Draw a card.

Arcane Infusion

Look at the top four cards of your library. You may reveal an instant or sorcery card from among them and put it into your hand. Put the rest on the bottom of your library in a random order.
Flashback {3}{U}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Leap of Flame

Replicate {U}{R} (When you cast this spell, copy it for each time you paid its replicate cost. You may choose new targets for the copies.)
Target creature gets +1/+0 and gains flying and first strike until end of turn.

Chemister's Trick

Target creature you don't control gets -2/-0 until end of turn and attacks this turn if able.
Overload {3}{U}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")