Cultist of the Absolute

Commander creatures you own get +3/+3 and have flying, deathtouch, "Ward—Pay 3 life," and "At the beginning of your upkeep, sacrifice a creature."

Gollum, Obsessed Stalker

Skulk (This creature can't be blocked by creatures with greater power.)
At the beginning of your end step, each opponent dealt combat damage this game by a creature named Gollum, Obsessed Stalker loses life equal to the amount of life you gained this turn.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature enters the battlefield under your control, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Firja, Judge of Valor

Flying, lifelink
Whenever you cast your second spell each turn, look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.

Noble Heritage

Commander creatures you own have "When this creature enters the battlefield and at the beginning of your upkeep, each player may put two +1/+1 counters on a creature they control. For each opponent who does, you gain protection from that player until your next turn." (You can't be targeted, dealt damage, or enchanted by anything controlled by that player.)

Sunscorch Regent

Flying
Whenever an opponent casts a spell, put a +1/+1 counter on Sunscorch Regent and you gain 1 life.

Daxos, Blessed by the Sun

Daxos's toughness is equal to your devotion to white. (Each {W} in the mana costs of permanents you control counts toward your devotion to white.)
Whenever another creature you control enters the battlefield or dies, you gain 1 life.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Liesa, Shroud of Dusk

Rather than pay {2} for each previous time you've cast this spell from the command zone this game, pay 2 life that many times.
Flying, lifelink
Whenever a player casts a spell, they lose 2 life.

Sarevok, Deathbringer

At the beginning of each player's end step, if no permanents left the battlefield this turn, that player loses X life, where X is Sarevok's power.
Choose a Background (You can have a Background as a second commander.)

Flaming Fist

Commander creatures you own have "Whenever this creature attacks, it gains double strike until end of turn."

Boon-Bringer Valkyrie

Backup 1 (When this creature enters the battlefield, put a +1/+1 counter on target creature. If that's another creature, it gains the following abilities until end of turn.)
Flying, first strike, lifelink

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Mask of Avacyn

Equipped creature gets +1/+2 and has hexproof. (It can't be the target of spells or abilities your opponents control.)
Equip {3}

Cruel Celebrant

Whenever Cruel Celebrant or another creature or planeswalker you control dies, each opponent loses 1 life and you gain 1 life.

Bonehoard

Living weapon (When this Equipment enters the battlefield, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +X/+X, where X is the number of creature cards in all graveyards.
Equip {2}

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Nykthos Paragon

Whenever you gain life, you may put that many +1/+1 counters on each creature you control. Do this only once each turn.

Sun Titan

Vigilance
Whenever Sun Titan enters the battlefield or attacks, you may return target permanent card with mana value 3 or less from your graveyard to the battlefield.

Agent of Masks

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Syndicate Heavy

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
At the beginning of each end step, if you gained 4 or more life this turn, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters the battlefield, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Rug of Smothering

Flying
Whenever a player casts a spell, they lose 1 life for each spell they've cast this turn.

Tivash, Gloom Summoner

Lifelink
At the beginning of your end step, if you gained life this turn, you may pay X life, where X is the amount of life you gained this turn. If you do, create an X/X black Demon creature token with flying.

Liesa, Forgotten Archangel

Flying, lifelink
Whenever another nontoken creature you control dies, return that card to its owner's hand at the beginning of the next end step.
If a creature an opponent controls would die, exile it instead.