Negate

Baleful Strix

Flying, deathtouch
When Baleful Strix enters the battlefield, draw a card.

Gixian Puppeteer

Whenever you draw your second card each turn, each opponent loses 2 life and you gain 2 life.
When Gixian Puppeteer dies, return another target creature card with mana value 3 or less from your graveyard to the battlefield.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Extinguish the Light

Destroy target creature or planeswalker. If its mana value was 3 or less, you gain 3 life.

Union of the Third Path

Draw a card, then you gain life equal to the number of cards in your hand.

Quick Study

Obscura Storefront

When Obscura Storefront enters the battlefield, sacrifice it. When you do, search your library for a basic Plains, Island, or Swamp card, put it onto the battlefield tapped, then shuffle and you gain 1 life.

Island

Temple of Silence

Temple of Silence enters the battlefield tapped.
When Temple of Silence enters the battlefield, scry 1.
{T}: Add {W} or {B}.

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

Ancestral Reminiscence

Sanctify

Destroy target artifact or enchantment. You gain 3 life.

Secret Rendezvous

You and target opponent each draw three cards.

Inspiring Overseer

Flying
When Inspiring Overseer enters the battlefield, you gain 1 life and draw a card.

Valorous Stance

Choose one —
• Target creature gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)
• Destroy target creature with toughness 4 or greater.

Twinblade Paladin

Whenever you gain life, put a +1/+1 counter on Twinblade Paladin.
As long as you have 25 or more life, Twinblade Paladin has double strike. (It deals both first-strike and regular combat damage.)

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.

Orzhov Basilica

Orzhov Basilica enters the battlefield tapped.
When Orzhov Basilica enters the battlefield, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Blossoming Calm

You gain hexproof until your next turn. You gain 2 life.
Rebound (If you cast this spell from your hand, exile it as it resolves. At the beginning of your next upkeep, you may cast this card from exile without paying its mana cost.)

Vampire Scrivener

Flying
Whenever you gain life during your turn, put a +1/+1 counter on Vampire Scrivener.
Whenever you lose life during your turn, put a +1/+1 counter on Vampire Scrivener.

Sejiri Refuge

Sejiri Refuge enters the battlefield tapped.
When Sejiri Refuge enters the battlefield, you gain 1 life.
{T}: Add {W} or {U}.

Arcane Sanctum

Arcane Sanctum enters the battlefield tapped.
{T}: Add {W}, {U}, or {B}.

Ornithopter of Paradise

Kwain, Itinerant Meddler

{T}: Each player may draw a card, then each player who drew a card this way gains 1 life.

Tranquil Cove

Tranquil Cove enters the battlefield tapped.
When Tranquil Cove enters the battlefield, you gain 1 life.
{T}: Add {W} or {U}.

Esper Charm

Choose one —
• Destroy target enchantment.
• Draw two cards.
• Target player discards two cards.

Plains

Jwar Isle Refuge

Jwar Isle Refuge enters the battlefield tapped.
When Jwar Isle Refuge enters the battlefield, you gain 1 life.
{T}: Add {U} or {B}.

Tainted Indulgence

Draw two cards. Then discard a card unless there are five or more mana values among cards in your graveyard.

Scion of the Swarm

Flying
Whenever you gain life, put a +1/+1 counter on Scion of the Swarm.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Dawnbringer Cleric

When Dawnbringer Cleric enters the battlefield, choose one —
• Cure Wounds — You gain 2 life.
• Dispel Magic — Destroy target enchantment.
• Gentle Repose — Exile target card from a graveyard.

Orzhov Signet

Orzhov Locket

{T}: Add {W} or {B}.
{W/B}{W/B}{W/B}{W/B}, {T}, Sacrifice Orzhov Locket: Draw two cards.

Sign in Blood

Target player draws two cards and loses 2 life.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Azorius Signet

Despark

Exile target permanent with mana value 4 or greater.

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Eriette's Lullaby

Destroy target tapped creature. You gain 2 life.

Keep Safe

Counter target spell that targets a permanent you control.
Draw a card.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Greed

Bonder's Ornament

{T}: Add one mana of any color.
{4}, {T}: Each player who controls a permanent named Bonder's Ornament draws a card.

Compulsive Research

Target player draws three cards. Then that player discards two cards unless they discard a land card.

Dawn Charm

Choose one —
• Prevent all combat damage that would be dealt this turn.
• Regenerate target creature.
• Counter target spell that targets you.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Kaya's Ghostform

Enchant creature or planeswalker you control
When enchanted permanent dies or is put into exile, return that card to the battlefield under your control.

Behold the Multiverse

Scry 2, then draw two cards.
Foretell {1}{U} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Path of Ancestry

Path of Ancestry enters the battlefield tapped.
{T}: Add one mana of any color in your commander's color identity. When that mana is spent to cast a creature spell that shares a creature type with your commander, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Blessing of Leeches

Flash
Enchant creature
At the beginning of your upkeep, you lose 1 life.
{0}: Regenerate enchanted creature.

Concentrate

Epicure of Blood

Swamp

Myr Convert

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
{T}, Pay 2 life: Add one mana of any color.

Retreat to Hagra

Landfall — Whenever a land enters the battlefield under your control, choose one —
• Target creature gets +1/+0 and gains deathtouch until end of turn.
• Each opponent loses 1 life and you gain 1 life.

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Queza, Augur of Agonies

Whenever you draw a card, target opponent loses 1 life and you gain 1 life.

Mortify

Frantic Search

Draw two cards, then discard two cards. Untap up to three lands.

Azorius Chancery

Azorius Chancery enters the battlefield tapped.
When Azorius Chancery enters the battlefield, return a land you control to its owner's hand.
{T}: Add {W}{U}.

Preordain

Scry 2, then draw a card. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Command Tower

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Dimir Signet

Utter End

Faithful Mending

You gain 2 life, draw two cards, then discard two cards.
Flashback {1}{W}{U} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Dimir Locket

{T}: Add {U} or {B}.
{U/B}{U/B}{U/B}{U/B}, {T}, Sacrifice Dimir Locket: Draw two cards.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Dismal Backwater

Dismal Backwater enters the battlefield tapped.
When Dismal Backwater enters the battlefield, you gain 1 life.
{T}: Add {U} or {B}.

Rain of Revelation

Scoured Barrens

Scoured Barrens enters the battlefield tapped.
When Scoured Barrens enters the battlefield, you gain 1 life.
{T}: Add {W} or {B}.

Mana Tithe

Counter target spell unless its controller pays {1}.

The Council of Four

Whenever a player draws their second card during their turn, you draw a card.
Whenever a player casts their second spell during their turn, you create a 2/2 white Knight creature token.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters the battlefield tapped unless you control two or more basic lands.

Dimir Aqueduct

Dimir Aqueduct enters the battlefield tapped.
When Dimir Aqueduct enters the battlefield, return a land you control to its owner's hand.
{T}: Add {U}{B}.

Spell Pierce

Counter target noncreature spell unless its controller pays {2}.

Sift

Azorius Locket

{T}: Add {W} or {U}.
{W/U}{W/U}{W/U}{W/U}, {T}, Sacrifice Azorius Locket: Draw two cards.

Painful Truths

Converge — You draw X cards and you lose X life, where X is the number of colors of mana spent to cast this spell.