Phyresis Outbreak

Each opponent gets a poison counter. Then each creature your opponents control gets -1/-1 until end of turn for each poison counter its controller has.

Kederekt Parasite

Whenever an opponent draws a card, if you control a red permanent, you may have Kederekt Parasite deal 1 damage to that player.

Tekuthal, Inquiry Dominus

Flying
If you would proliferate, proliferate twice instead.
{1}{U/P}{U/P}, Remove three counters from among other artifacts, creatures, and planeswalkers you control: Put an indestructible counter on Tekuthal, Inquiry Dominus. ({U/P} can be paid with either {U} or 2 life.)

Morphic Pool

Morphic Pool enters tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Ulamog, the Infinite Gyre

When you cast this spell, destroy target permanent.
Indestructible
Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents of their choice.)
When Ulamog, the Infinite Gyre is put into a graveyard from anywhere, its owner shuffles their graveyard into their library.

Distorted Curiosity

Corrupted — This spell costs {2} less to cast if an opponent has three or more poison counters.
Draw two cards.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Corrupted Conscience

Enchant creature
You control enchanted creature.
Enchanted creature has infect. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Graven Cairns

{T}: Add {C}.
{B/R}, {T}: Add {B}{B}, {B}{R}, or {R}{R}.

Desolation Twin

When you cast this spell, create a 10/10 colorless Eldrazi creature token.

Volt Charge

Volt Charge deals 3 damage to any target. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Chancellor of the Dross

You may reveal this card from your opening hand. If you do, at the beginning of the first upkeep, each opponent loses 3 life, then you gain life equal to the life lost this way.
Flying, lifelink

Priest of Urabrask

When Priest of Urabrask enters, add {R}{R}{R}.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Barrage Tyrant

Devoid (This card has no color.)
{2}{R}, Sacrifice another colorless creature: Barrage Tyrant deals damage equal to the sacrificed creature's power to any target.

Darksteel Monolith

Indestructible
Once each turn, you may pay {0} rather than pay the mana cost for a colorless spell you cast from your hand.

Phyrexian Delver

When Phyrexian Delver enters, return target creature card from your graveyard to the battlefield. You lose life equal to that card's mana value.

Void Winnower

Your opponents can't cast spells with even mana values. (Zero is even.)
Your opponents can't block with creatures with even mana values.

Blighted Agent

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Blighted Agent can't be blocked.

Mycosynth Lattice

All permanents are artifacts in addition to their other types.
All cards that aren't on the battlefield, spells, and permanents are colorless.
Players may spend mana as though it were mana of any color.

Ashnod the Uncaring

Deathtouch
Whenever you activate an ability of an artifact or creature that isn't a mana ability, if one or more permanents were sacrificed to activate it, you may copy that ability. You may choose new targets for the copy. (Sacrificing an artifact for mana to activate an ability doesn't count.)

Drowner of Hope

Devoid (This card has no color.)
When Drowner of Hope enters, create two 1/1 colorless Eldrazi Scion creature tokens. They have "Sacrifice this creature: Add {C}."
Sacrifice an Eldrazi Scion: Tap target creature.

Blightsteel Colossus

Trample, infect, indestructible
If Blightsteel Colossus would be put into a graveyard from anywhere, reveal Blightsteel Colossus and shuffle it into its owner's library instead.

Chromatic Lantern

Lands you control have "{T}: Add one mana of any color."
{T}: Add one mana of any color.

Swamp

Glistening Oil

Enchant creature
Enchanted creature has infect.
At the beginning of your upkeep, put a -1/-1 counter on enchanted creature.
When Glistening Oil is put into a graveyard from the battlefield, return Glistening Oil to its owner's hand.

Grim Affliction

Put a -1/-1 counter on target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Corrupted Resolve

Counter target spell if its controller is poisoned.

Sol Talisman

Suspend 3—{1} (Rather than cast this card from your hand, pay {1} and exile it with three time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
{T}: Add {C}{C}.

Darksteel Forge

Artifacts you control have indestructible. (Effects that say "destroy" don't destroy them. Artifact creatures with indestructible can't be destroyed by damage.)

Grafted Exoskeleton

Equipped creature gets +2/+2 and has infect. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever Grafted Exoskeleton becomes unattached from a permanent, sacrifice that permanent.
Equip {2}

Crypt of the Eternals

When Crypt of the Eternals enters, you gain 1 life.
{T}: Add {C}.
{1}, {T}: Add {U}, {B}, or {R}.

Fuel for the Cause

Counter target spell, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Urza's Tower

{T}: Add {C}. If you control an Urza's Mine and an Urza's Power-Plant, add {C}{C}{C} instead.

Radstorm

Storm (When you cast this spell, copy it for each spell cast before it this turn.)
Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Diabolic Intent

As an additional cost to cast this spell, sacrifice a creature.
Search your library for a card, put that card into your hand, then shuffle.

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Vraska's Fall

Each opponent sacrifices a creature or planeswalker of their choice and gets a poison counter.

Phyresis

Enchant creature
Enchanted creature has infect. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Relic of Sauron

{T}: Add two mana in any combination of {U}, {B}, and/or {R}.
{3}, {T}: Draw two cards, then discard a card.

Blightbelly Rat

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Blightbelly Rat dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Diabolic Revelation

Search your library for up to X cards, put those cards into your hand, then shuffle.

Glistening Sphere

Glistening Sphere enters tapped.
When Glistening Sphere enters, proliferate.
{T}: Add one mana of any color.
Corrupted — {T}: Add three mana of any one color. Activate only if an opponent has three or more poison counters.

Phyrexian Triniform

When Phyrexian Triniform dies, create three 3/3 colorless Phyrexian Golem artifact creature tokens.
Encore {12} ({12}, Exile this card from your graveyard: For each opponent, create a token copy that attacks that opponent this turn if able. They gain haste. Sacrifice them at the beginning of the next end step. Activate only as a sorcery.)

Island

Forerunner of Slaughter

Devoid (This card has no color.)
{1}: Target colorless creature gains haste until end of turn.

Ruination Guide

Devoid (This card has no color.)
Ingest (Whenever this creature deals combat damage to a player, that player exiles the top card of their library.)
Other colorless creatures you control get +1/+0.

Moltensteel Dragon

({R/P} can be paid with either {R} or 2 life.)
Flying
{R/P}: Moltensteel Dragon gets +1/+0 until end of turn.

Inexorable Tide

Whenever you cast a spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Luxury Suite

Luxury Suite enters tapped unless you have two or more opponents.
{T}: Add {B} or {R}.

Artisan of Kozilek

When you cast this spell, you may return target creature card from your graveyard to the battlefield.
Annihilator 2 (Whenever this creature attacks, defending player sacrifices two permanents of their choice.)

Breaker of Armies

All creatures able to block Breaker of Armies do so.

Long-Term Plans

Search your library for a card, then shuffle and put that card third from the top.

Chancellor of the Spires

You may reveal this card from your opening hand. If you do, at the beginning of the first upkeep, each opponent mills seven cards.
Flying
When Chancellor of the Spires enters, you may cast target instant or sorcery card from an opponent's graveyard without paying its mana cost.

Molten Psyche

Each player shuffles the cards from their hand into their library, then draws that many cards.
Metalcraft — If you control three or more artifacts, Molten Psyche deals damage to each opponent equal to the number of cards that player has drawn this turn.

Endless One

Endless One enters with X +1/+1 counters on it.

Vile Aggregate

Devoid (This card has no color.)
Vile Aggregate's power is equal to the number of colorless creatures you control.
Trample
Ingest (Whenever this creature deals combat damage to a player, that player exiles the top card of their library.)

Solphim, Mayhem Dominus

If a source you control would deal noncombat damage to an opponent or a permanent an opponent controls, it deals double that damage to that player or permanent instead.
{1}{R/P}{R/P}, Discard two cards: Put an indestructible counter on Solphim, Mayhem Dominus. ({R/P} can be paid with either {R} or 2 life.)

Entomber Exarch

When Entomber Exarch enters, choose one —
• Return target creature card from your graveyard to your hand.
• Target opponent reveals their hand. You choose a noncreature card from it. That player discards that card.

Spread the Sickness

Destroy target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Skithiryx, the Blight Dragon

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Skithiryx, the Blight Dragon gains haste until end of turn.
{B}{B}: Regenerate Skithiryx.

Training Center

Training Center enters tapped unless you have two or more opponents.
{T}: Add {U} or {R}.

Windfall

Each player discards their hand, then draws cards equal to the greatest number of cards a player discarded this way.

Throne of Geth

{T}, Sacrifice an artifact: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Urza's Power Plant

{T}: Add {C}. If you control an Urza's Mine and an Urza's Tower, add {C}{C} instead.

Tainted Strike

Target creature gets +1/+0 and gains infect until end of turn. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Crumbling Necropolis

Crumbling Necropolis enters tapped.
{T}: Add {U}, {B}, or {R}.

Dark Petition

Search your library for a card, put that card into your hand, then shuffle.
Spell mastery — If there are two or more instant and/or sorcery cards in your graveyard, add {B}{B}{B}.

Caress of Phyrexia

Target player draws three cards, loses 3 life, and gets three poison counters.

Prologue to Phyresis

Each opponent gets a poison counter.
Draw a card.

Geth's Summons

Return up to one target creature card from your graveyard to the battlefield.
Corrupted — For each opponent who has three or more poison counters as you cast this spell, put up to one target creature card from that player's graveyard onto the battlefield under your control.

Karn's Bastion

{T}: Add {C}.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Phyrexian Metamorph

({U/P} can be paid with either {U} or 2 life.)
You may have Phyrexian Metamorph enter as a copy of any artifact or creature on the battlefield, except it's an artifact in addition to its other types.

Fallen Ferromancer

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{1}{R}, {T}: Fallen Ferromancer deals 1 damage to any target.

Reaper of Sheoldred

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever a source deals damage to Reaper of Sheoldred, that source's controller gets a poison counter.

Ichorclaw Myr

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever Ichorclaw Myr becomes blocked, it gets +2/+2 until end of turn.

Mountain

Conduit of Ruin

When you cast this spell, you may search your library for a colorless creature card with mana value 7 or greater, reveal it, then shuffle and put that card on top.
The first creature spell you cast each turn costs {2} less to cast.

Viral Drake

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{3}{U}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Flayer Drone

Devoid (This card has no color.)
First strike
Whenever another colorless creature you control enters, target opponent loses 1 life.

Sol Ring

Profane Tutor

Suspend 2—{1}{B} (Rather than cast this card from your hand, pay {1}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search your library for a card, put that card into your hand, then shuffle.

Sunken Ruins

{T}: Add {C}.
{U/B}, {T}: Add {U}{U}, {U}{B}, or {B}{B}.

Urza's Mine

{T}: Add {C}. If you control an Urza's Power-Plant and an Urza's Tower, add {C}{C} instead.

Scheming Aspirant

Whenever you proliferate, each opponent loses 2 life and you gain 2 life.

Cascade Bluffs

{T}: Add {C}.
{U/R}, {T}: Add {U}{U}, {U}{R}, or {R}{R}.

Capricious Hellraiser

This spell costs {3} less to cast if you have nine or more cards in your graveyard.
Flying
When Capricious Hellraiser enters, exile three cards at random from your graveyard. Choose a noncreature, nonland card from among them and copy it. You may cast the copy without paying its mana cost.