Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Clackbridge Troll

Trample, haste
When Clackbridge Troll enters, target opponent creates three 0/1 white Goat creature tokens.
At the beginning of combat on your turn, any opponent may sacrifice a creature of their choice. If a player does, tap Clackbridge Troll, you gain 3 life, and you draw a card.

Gallowbraid

Trample
Cumulative upkeep—Pay 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Infernal Contract

Draw four cards. You lose half your life, rounded up.

Infernal Grasp

Destroy target creature. You lose 2 life.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Garza's Assassin

Sacrifice Garza's Assassin: Destroy target nonblack creature.
Recover—Pay half your life, rounded up. (When another creature is put into your graveyard from the battlefield, you may pay half your life, rounded up. If you do, return this card from your graveyard to your hand. Otherwise, exile this card.)

Ebonblade Reaper

Whenever Ebonblade Reaper attacks, you lose half your life, rounded up.
Whenever Ebonblade Reaper deals combat damage to a player, that player loses half their life, rounded up.
Morph {3}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Dark Ritual

Pristine Talisman

Crypt Incursion

Exile all creature cards from target player's graveyard. You gain 3 life for each card exiled this way.

Slaughter

Buyback—Pay 4 life. (You may pay 4 life in addition to any other costs as you cast this spell. If you do, put this card into your hand as it resolves.)
Destroy target nonblack creature. It can't be regenerated.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Bubbling Muck

Until end of turn, whenever a player taps a Swamp for mana, that player adds an additional {B}.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Hexavus

Flying
Hexavus enters with six +1/+1 counters on it.
{1}, Remove a +1/+1 counter from Hexavus: Put a flying counter on another target creature.
{1}, Remove a counter from another creature you control: Put a +1/+1 counter on Hexavus.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.

Murderous Betrayal

{B}{B}, Pay half your life, rounded up: Destroy target nonblack creature. It can't be regenerated.

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Cabal Stronghold

{T}: Add {C}.
{3}, {T}: Add {B} for each basic Swamp you control.

Whip of Erebos

Creatures you control have lifelink.
{2}{B}{B}, {T}: Return target creature card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step. If it would leave the battlefield, exile it instead of putting it anywhere else. Activate only as a sorcery.

Phyrexian Processor

As Phyrexian Processor enters, pay any amount of life.
{4}, {T}: Create an X/X black Phyrexian Minion creature token, where X is the life paid as Phyrexian Processor entered.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Witch's Cottage

({T}: Add {B}.)
Witch's Cottage enters tapped unless you control three or more other Swamps.
When Witch's Cottage enters untapped, you may put target creature card from your graveyard on top of your library.

Mortarion, Daemon Primarch

Flying
Primarch of the Death Guard — At the beginning of your end step, you may pay {X}. If you do, create X 2/2 black Astartes Warrior creature tokens with menace. X can't be greater than the amount of life you lost this turn.

Triskaidekaphobia

At the beginning of your upkeep, choose one —
• Each player with exactly 13 life loses the game, then each player gains 1 life.
• Each player with exactly 13 life loses the game, then each player loses 1 life.

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Sol Ring

Diamond Mare

As Diamond Mare enters, choose a color.
Whenever you cast a spell of the chosen color, you gain 1 life.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Reckless Spite

Destroy two target nonblack creatures. You lose 5 life.

Bond of Agony

As an additional cost to cast this spell, pay X life.
Each other player loses X life.

Marshland Bloodcaster

Flying
{1}{B}, {T}: Rather than pay the mana cost of the next spell you cast this turn, you may pay life equal to that spell's mana value.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Eternity Vessel

Eternity Vessel enters with X charge counters on it, where X is your life total.
Landfall — Whenever a land you control enters, you may have your life total become the number of charge counters on Eternity Vessel.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.

Magus of the Mirror

{T}, Sacrifice Magus of the Mirror: Exchange life totals with target opponent. Activate only during your upkeep.

Slaughter Pact

Destroy target nonblack creature.
At the beginning of your next upkeep, pay {2}{B}. If you don't, you lose the game.

Pact Weapon

As long as Pact Weapon is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Sign in Blood

Target player draws two cards and loses 2 life.

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Demon's Horn

Whenever a player casts a black spell, you may gain 1 life.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Staff of the Death Magus

Whenever you cast a black spell or a Swamp you control enters, you gain 1 life.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Devour in Shadow

Destroy target creature. It can't be regenerated. You lose life equal to that creature's toughness.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Burnished Hart

{3}, Sacrifice this creature: Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Charcoal Diamond

Charcoal Diamond enters tapped.
{T}: Add {B}.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Greed

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Swamp

Morinfen

Flying
Cumulative upkeep—Pay 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Dread Presence

Whenever a Swamp you control enters, choose one —
• You draw a card and you lose 1 life.
• Dread Presence deals 2 damage to any target and you gain 2 life.

Leaden Myr

Pain's Reward

Each player may bid life. You start the bidding with a bid of any number. In turn order, each player may top the high bid. The bidding ends if the high bid stands. The high bidder loses life equal to the high bid and draws four cards.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Platinum Angel

Flying
You can't lose the game and your opponents can't win the game.

Mortuary Mire

Mortuary Mire enters tapped.
When Mortuary Mire enters, you may put target creature card from your graveyard on top of your library.
{T}: Add {B}.

Erebos's Intervention

Choose one —
• Target creature gets -X/-X until end of turn. You gain X life.
• Exile up to twice X target cards from graveyards.

Font of Agonies

Whenever you pay life, put that many blood counters on Font of Agonies.
{1}{B}, Remove four blood counters from Font of Agonies: Destroy target creature.

The Book of Vile Darkness

At the beginning of your end step, if you lost 2 or more life this turn, create a 2/2 black Zombie creature token.
{T}, Exile The Book of Vile Darkness and artifacts you control named Eye of Vecna and Hand of Vecna: Create Vecna, a legendary 8/8 black Zombie God creature token with indestructible and all triggered abilities of the exiled cards.