Chancellor of the Dross

You may reveal this card from your opening hand. If you do, at the beginning of the first upkeep, each opponent loses 3 life, then you gain life equal to the life lost this way.
Flying, lifelink

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Court of Ambition

When Court of Ambition enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Agent of the Fates

Deathtouch
Heroic — Whenever you cast a spell that targets Agent of the Fates, each opponent sacrifices a creature of their choice.

Dreg Recycler

{T}, Sacrifice an artifact or creature: Each opponent loses 1 life and you gain 1 life.

Dire Fleet Ravager

Menace, deathtouch
When Dire Fleet Ravager enters, each player loses a third of their life, rounded up.

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Cauldron Familiar

When Cauldron Familiar enters, each opponent loses 1 life and you gain 1 life.
Sacrifice a Food: Return Cauldron Familiar from your graveyard to the battlefield.

Soul Enervation

Flash
When Soul Enervation enters, target creature gets -4/-4 until end of turn.
Whenever one or more creature cards leave your graveyard, each opponent loses 1 life and you gain 1 life.

Elderfang Venom

Attacking Elves you control have deathtouch.
Whenever an Elf you control dies, each opponent loses 1 life and you gain 1 life.

Dimir House Guard

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
Sacrifice a creature: Regenerate Dimir House Guard.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Citadel Siege

As Citadel Siege enters, choose Khans or Dragons.
• Khans — At the beginning of combat on your turn, put two +1/+1 counters on target creature you control.
• Dragons — At the beginning of combat on each opponent's turn, tap target creature that player controls.

Subversion

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Blistergrub

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
When Blistergrub dies, each opponent loses 2 life.

Champions of Minas Tirith

When Champions of Minas Tirith enters, you become the monarch.
At the beginning of combat on each opponent's turn, if you're the monarch, that opponent may pay {X}, where X is the number of cards in their hand. If they don't, they can't attack you this combat.

Cabal Paladin

Whenever you cast a historic spell, Cabal Paladin deals 2 damage to each opponent. (Artifacts, legendaries, and Sagas are historic.)

Archfiend of Depravity

Flying
At the beginning of each opponent's end step, that player chooses up to two creatures they control, then sacrifices the rest.

Eriette of the Charmed Apple

Each creature that's enchanted by an Aura you control can't attack you or planeswalkers you control.
At the beginning of your end step, each opponent loses X life and you gain X life, where X is the number of Auras you control.

Bastion of Remembrance

When Bastion of Remembrance enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Bontu the Glorified

Menace, indestructible
Bontu the Glorified can't attack or block unless a creature died under your control this turn.
{1}{B}, Sacrifice another creature: Scry 1. Each opponent loses 1 life and you gain 1 life.

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Aurora of Emrakul

Flying, deathtouch
Whenever Aurora of Emrakul attacks, each opponent loses 3 life.

Cryptolith Fragment

Cryptolith Fragment enters tapped.
{T}: Add one mana of any color. Each player loses 1 life.
At the beginning of your upkeep, if each player has 10 or less life, transform Cryptolith Fragment.

Cryptolith Fragment // Aurora of Emrakul

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Impact Tremors

Whenever a creature you control enters, this enchantment deals 1 damage to each opponent.

Dark Suspicions

At the beginning of each opponent's upkeep, that player loses X life, where X is the number of cards in that player's hand minus the number of cards in your hand.

Grasp of Fate

When Grasp of Fate enters, for each opponent, exile up to one target nonland permanent that player controls until Grasp of Fate leaves the battlefield. (Those permanents return under their owners' control.)

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature you control enters, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Agent of Masks

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Etched Familiar

When Etched Familiar dies, each opponent loses 2 life and you gain 2 life.

Corpse Knight

Whenever another creature you control enters, each opponent loses 1 life.

Web of Inertia

At the beginning of combat on each opponent's turn, that player may exile a card from their graveyard. If the player doesn't, creatures they control can't attack you this turn.

Faerie Bladecrafter

Flying
Whenever one or more Faeries you control deal combat damage to a player, put a +1/+1 counter on Faerie Bladecrafter.
When Faerie Bladecrafter dies, each opponent loses X life and you gain X life, where X is its power.

Acolyte of Aclazotz

{T}, Sacrifice another creature or artifact: Each opponent loses 1 life and you gain 1 life.

Sanctum of Stone Fangs

At the beginning of your first main phase, each opponent loses X life and you gain X life, where X is the number of Shrines you control.

Fight or Flight

At the beginning of combat on each opponent's turn, separate all creatures that player controls into two piles. Only creatures in the pile of their choice can attack this turn.

Angelic Arbiter

Flying
Each opponent who cast a spell this turn can't attack with creatures.
Each opponent who attacked with a creature this turn can't cast spells.

Warleader's Call

Creatures you control get +1/+1.
Whenever a creature you control enters, Warleader's Call deals 1 damage to each opponent.

Cruel Celebrant

Whenever Cruel Celebrant or another creature or planeswalker you control dies, each opponent loses 1 life and you gain 1 life.

Diregraf Scavenger

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
When Diregraf Scavenger enters, exile up to one target card from a graveyard. If a creature card was exiled this way, each opponent loses 2 life and you gain 2 life.

Grim Guardian

Constellation — Whenever Grim Guardian or another enchantment you control enters, each opponent loses 1 life.

Lampad of Death's Vigil

{1}, Sacrifice a creature: Each opponent loses 1 life and you gain 1 life.

Underworld Coinsmith

Constellation — Whenever Underworld Coinsmith or another enchantment you control enters, you gain 1 life.
{W}{B}, Pay 1 life: Each opponent loses 1 life.

Fiery Inscription

When Fiery Inscription enters, the Ring tempts you.
Whenever you cast an instant or sorcery spell, Fiery Inscription deals 2 damage to each opponent.

Martyr's Bond

Whenever Martyr's Bond or another nonland permanent you control is put into a graveyard from the battlefield, each opponent sacrifices a permanent of their choice that shares a card type with it.

Falkenrath Noble

Flying
Whenever Falkenrath Noble or another creature dies, target player loses 1 life and you gain 1 life.

Dreadhound

When Dreadhound enters, mill three cards. (Put the top three cards of your library into your graveyard.)
Whenever a creature dies or a creature card is put into a graveyard from a library, each opponent loses 1 life.

Retreat to Hagra

Landfall — Whenever a land you control enters, choose one —
• Target creature gets +1/+0 and gains deathtouch until end of turn.
• Each opponent loses 1 life and you gain 1 life.

Dusk Mangler

As an additional cost to cast this spell, sacrifice a creature, discard a card, or pay 4 life.
When Dusk Mangler enters, each opponent sacrifices a creature of their choice, discards a card, and loses 4 life.

Arrogant Outlaw

When Arrogant Outlaw enters, if an opponent lost life this turn, each opponent loses 2 life and you gain 2 life.

Ill-Gotten Inheritance

At the beginning of your upkeep, Ill-Gotten Inheritance deals 1 damage to each opponent and you gain 1 life.
{5}{B}, Sacrifice Ill-Gotten Inheritance: It deals 4 damage to target opponent and you gain 4 life.

Palace Siege

As Palace Siege enters, choose Khans or Dragons.
• Khans — At the beginning of your upkeep, return target creature card from your graveyard to your hand.
• Dragons — At the beginning of your upkeep, each opponent loses 2 life and you gain 2 life.

Mystic Redaction

At the beginning of your upkeep, scry 1.
Whenever you discard a card, each opponent mills two cards. (They put the top two cards of their library into their graveyard.)

Butcher of Malakir

Flying
Whenever Butcher of Malakir or another creature you control dies, each opponent sacrifices a creature of their choice.

Crackling Perimeter

Tap an untapped Gate you control: Crackling Perimeter deals 1 damage to each opponent.

Battlefield Butcher

{5}, {T}: Each opponent loses 2 life. This ability costs {1} less to activate for each creature card in your graveyard.

Price of Knowledge

Players have no maximum hand size.
At the beginning of each opponent's upkeep, Price of Knowledge deals damage to that player equal to the number of cards in that player's hand.

Protection Racket

At the beginning of your upkeep, repeat the following process for each opponent in turn order. Reveal the top card of your library. That player may pay life equal to that card's mana value. If they do, exile that card. Otherwise, put it into your hand.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Faith of the Devoted

Whenever you cycle or discard a card, you may pay {1}. If you do, each opponent loses 2 life and you gain 2 life.

Agent of the Iron Throne

Commander creatures you own have "Whenever an artifact or creature you control is put into a graveyard from the battlefield, each opponent loses 1 life."

Denethor, Ruling Steward

At the beginning of your end step, if a creature died under your control this turn, create a 1/1 white Human Soldier creature token.
{2}, Sacrifice another creature: Each opponent loses 1 life and you gain 1 life.

Eradicator Valkyrie

Flying, lifelink, hexproof from planeswalkers
Boast — {1}{B}, Sacrifice a creature: Each opponent sacrifices a creature or planeswalker. (Activate only if this creature attacked this turn and only once each turn.)