Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Go for the Throat

Phyrexian Tribute

As an additional cost to cast this spell, sacrifice two creatures.
Destroy target artifact.

Spark Harvest

As an additional cost to cast this spell, sacrifice a creature or pay {3}{B}.
Destroy target creature or planeswalker.

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature you control enters, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Pack Rat

Pack Rat's power and toughness are each equal to the number of Rats you control.
{2}{B}, Discard a card: Create a token that's a copy of Pack Rat.

Swarmyard

{T}: Add {C}.
{T}: Regenerate target Insect, Rat, Spider, or Squirrel. (The next time it would be destroyed this turn, instead tap it, remove it from combat, and heal all damage on it.)

Relentless Rats

Relentless Rats gets +1/+1 for each other creature on the battlefield named Relentless Rats.
A deck can have any number of cards named Relentless Rats.

Blightbelly Rat

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Blightbelly Rat dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Locust Miser

Each opponent's maximum hand size is reduced by two.

Palace Siege

As Palace Siege enters, choose Khans or Dragons.
• Khans — At the beginning of your upkeep, return target creature card from your graveyard to your hand.
• Dragons — At the beginning of your upkeep, each opponent loses 2 life and you gain 2 life.

Stronghold Rats

Shadow (This creature can block or be blocked by only creatures with shadow.)
Whenever Stronghold Rats deals combat damage to a player, each player discards a card.

Nyx Lotus

Nyx Lotus enters tapped.
{T}: Choose a color. Add an amount of mana of that color equal to your devotion to that color. (Your devotion to a color is the number of mana symbols of that color in the mana costs of permanents you control.)

Hero's Downfall

Burglar Rat

When Burglar Rat enters, each opponent discards a card.

Piper of the Swarm

Rats you control have menace.
{1}{B}, {T}: Create a 1/1 black Rat creature token.
{2}{B}{B}, {T}, Sacrifice three Rats: Gain control of target creature.

Ratcatcher

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
At the beginning of your upkeep, you may search your library for a Rat card, reveal it, put it into your hand, then shuffle.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Oversold Cemetery

At the beginning of your upkeep, if you have four or more creature cards in your graveyard, you may return target creature card from your graveyard to your hand.

Sign in Blood

Target player draws two cards and loses 2 life.

Karumonix, the Rat King

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
Other Rats you control have toxic 1.
When Karumonix enters, look at the top five cards of your library. You may reveal any number of Rat cards from among them and put the revealed cards into your hand. Put the rest on the bottom of your library in a random order.

Victimize

Choose two target creature cards in your graveyard. Sacrifice a creature. If you do, return the chosen cards to the battlefield tapped.

Succumb to Temptation

Agent of the Iron Throne

Commander creatures you own have "Whenever an artifact or creature you control is put into a graveyard from the battlefield, each opponent loses 1 life."

Gnat Miser

Each opponent's maximum hand size is reduced by one.

Crushing Disappointment

Each player loses 2 life. You draw two cards.

Replicating Ring

{T}: Add one mana of any color.
At the beginning of your upkeep, put a night counter on Replicating Ring. Then if it has eight or more night counters on it, remove all of them and create eight colorless snow artifact tokens named Replicated Ring with "{T}: Add one mana of any color."

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Painful Lesson

Village Rites

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

Foreboding Fruit

Target player draws two cards and loses 2 life.
Adamant — If at least three black mana was spent to cast this spell, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")

Kindred Dominance

Choose a creature type. Destroy all creatures that aren't of the chosen type.

Ichor Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Ichor Rats enters, each player gets a poison counter.

Thrumming Stone

Spells you cast have ripple 4. (Whenever you cast a spell, you may reveal the top four cards of your library. You may cast spells with the same name as that spell from among the revealed cards without paying their mana costs. Put the rest on the bottom of your library.)

Thought Vessel

Ogre Slumlord

Whenever another nontoken creature dies, you may create a 1/1 black Rat creature token.
Rats you control have deathtouch.

Blood Pact

Sol Ring

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Swamp

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Crypt Rats

{X}: Crypt Rats deals X damage to each creature and each player. Spend only black mana on X.