Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Rowan's Grim Search

Bargain (You may sacrifice an artifact, enchantment, or token as you cast this spell.)
If this spell was bargained, look at the top four cards of your library, then put up to two of them back on top of your library in any order and the rest into your graveyard.
You draw two cards and you lose 2 life.

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Braids, Arisen Nightmare

At the beginning of your end step, you may sacrifice an artifact, creature, enchantment, land, or planeswalker. If you do, each opponent may sacrifice a permanent of their choice that shares a card type with it. For each opponent who doesn't, that player loses 2 life and you draw a card.

Swamp

Mithril Coat

Flash
Indestructible
When Mithril Coat enters, attach it to target legendary creature you control.
Equipped creature has indestructible.
Equip {3}

Infernal Grasp

Destroy target creature. You lose 2 life.

Moonlight Bargain

Look at the top five cards of your library. For each card, put that card into your graveyard unless you pay 2 life. Then put the rest into your hand.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Bitter Triumph

As an additional cost to cast this spell, discard a card or pay 3 life.
Destroy target creature or planeswalker.

Dark Ritual

Bog Witch

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Eldritch Pact

Target player draws X cards and loses X life, where X is the number of cards in their graveyard.

Not Dead After All

Until end of turn, target creature you control gains "When this creature dies, return it to the battlefield tapped under its owner's control, then create a Wicked Role token attached to it." (Enchanted creature gets +1/+1. When this Aura is put into a graveyard, each opponent loses 1 life.)

No Mercy

Whenever a creature deals damage to you, destroy it.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Phyrexian Reclamation

{1}{B}, Pay 2 life: Return target creature card from your graveyard to your hand.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Undying Malice

Until end of turn, target creature gains "When this creature dies, return it to the battlefield tapped under its owner's control with a +1/+1 counter on it."

Mikokoro, Center of the Sea

{T}: Add {C}.
{2}, {T}: Each player draws a card.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Knight of Dusk's Shadow

Menace (This creature can't be blocked except by two or more creatures.)
Your opponents can't gain life.
{1}{B}: Knight of Dusk's Shadow gets +1/+1 until end of turn.

Elder Brain

Menace
Whenever Elder Brain attacks a player, exile all cards from that player's hand, then they draw that many cards. You may play lands and cast spells from among the exiled cards for as long as they remain exiled. If you cast a spell this way, you may spend mana as though it were mana of any color to cast it.

Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle Decree of Pain, all creatures get -2/-2 until end of turn.

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Temple Bell

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Ashnod's Intervention

Until end of turn, target creature gets +2/+0 and gains "When this creature dies or is put into exile from the battlefield, return it to its owner's hand."

Baleful Mastery

You may pay {1}{B} rather than pay this spell's mana cost.
If the {1}{B} cost was paid, an opponent draws a card.
Exile target creature or planeswalker.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Hellish Rebuke

Until end of turn, permanents your opponents control gain "When this permanent deals damage to the player who cast Hellish Rebuke, sacrifice this permanent. You lose 2 life."

Bitterblossom

At the beginning of your upkeep, you lose 1 life and create a 1/1 black Faerie Rogue creature token with flying.

Orcish Bowmasters

Flash
When Orcish Bowmasters enters and whenever an opponent draws a card except the first one they draw in each of their draw steps, Orcish Bowmasters deals 1 damage to any target. Then amass Orcs 1.

Damnable Pact

Target player draws X cards and loses X life.

Teferi's Puzzle Box

At the beginning of each player's draw step, that player puts the cards in their hand on the bottom of their library in any order, then draws that many cards.

Greed

Supernatural Stamina

Until end of turn, target creature gets +2/+0 and gains "When this creature dies, return it to the battlefield tapped under its owner's control."

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Howling Mine

At the beginning of each player's draw step, if Howling Mine is untapped, that player draws an additional card.