Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Vendetta

Destroy target nonblack creature. It can't be regenerated. You lose life equal to that creature's toughness.

Ambition's Cost

You draw three cards and you lose 3 life.

Obelisk of Esper

Vessel of Endless Rest

When Vessel of Endless Rest enters, put target card from a graveyard on the bottom of its owner's library.
{T}: Add one mana of any color.

Curse of the Swine

Exile X target creatures. For each creature exiled this way, its controller creates a 2/2 green Boar creature token.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Sign in Blood

Target player draws two cards and loses 2 life.

Sphinx of the Steel Wind

Flying, first strike, vigilance, lifelink, protection from red and from green

Hedron Archive

{T}: Add {C}{C}.
{2}, {T}, Sacrifice this artifact: Draw two cards.

Negate

Despark

Exile target permanent with mana value 4 or greater.

Angelic Accord

At the beginning of each end step, if you gained 4 or more life this turn, create a 4/4 white Angel creature token with flying.

Mortify

Teysa, Envoy of Ghosts

Vigilance, protection from creatures
Whenever a creature deals combat damage to you, destroy that creature. Create a 1/1 white and black Spirit creature token with flying.

Swamp

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Orzhov Cluestone

{T}: Add {W} or {B}.
{W}{B}, {T}, Sacrifice Orzhov Cluestone: Draw a card.

Azorius Cluestone

{T}: Add {W} or {U}.
{W}{U}, {T}, Sacrifice Azorius Cluestone: Draw a card.

Dimir Guildgate

This land enters tapped.
{T}: Add {U} or {B}.

Whispersilk Cloak

Equipped creature can't be blocked and has shroud. (It can't be the target of spells or abilities.)
Equip {2}

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Dissipate

Counter target spell. If that spell is countered this way, exile it instead of putting it into its owner's graveyard.

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Dimir Signet

Honden of Seeing Winds

At the beginning of your upkeep, draw a card for each Shrine you control.

Orzhov Signet

Salvager of Secrets

When Salvager of Secrets enters, return target instant or sorcery card from your graveyard to your hand.

Azorius Signet

Vampire Nighthawk

Flying
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Orzhov Guildgate

This land enters tapped.
{T}: Add {W} or {B}.

Pontiff of Blight

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Other creatures you control have extort. (If a creature has multiple instances of extort, each triggers separately.)

Sphere of the Suns

Sphere of the Suns enters tapped and with three charge counters on it.
{T}, Remove a charge counter from Sphere of the Suns: Add one mana of any color.

Unwind

Counter target noncreature spell. Untap up to three lands.

Mnemonic Wall

Defender
When Mnemonic Wall enters, you may return target instant or sorcery card from your graveyard to your hand.

Man-o'-War

When Man-o'-War enters, return target creature to its owner's hand.

Bloodthirsty Blade

Equipped creature gets +2/+0 and is goaded. (It attacks each combat if able and attacks a player other than you if able.)
{1}: Attach Bloodthirsty Blade to target creature an opponent controls. Activate only as a sorcery.

Cloudblazer

Flying
When this creature enters, you gain 2 life and draw two cards.

Fblthp, the Lost

When Fblthp, the Lost enters, draw a card. If it entered from your library or was cast from your library, draw two cards instead.
When Fblthp becomes the target of a spell, shuffle Fblthp into its owner's library.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Future Sight

Play with the top card of your library revealed.
You may play lands and cast spells from the top of your library.

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Mask of Avacyn

Equipped creature gets +1/+2 and has hexproof. (It can't be the target of spells or abilities your opponents control.)
Equip {3}

Serra Avatar

Serra Avatar's power and toughness are each equal to your life total.
When Serra Avatar is put into a graveyard from anywhere, shuffle it into its owner's library.

Honden of Night's Reach

At the beginning of your upkeep, target opponent discards a card for each Shrine you control.

Disdainful Stroke

Counter target spell with mana value 4 or greater.

Manalith

Nightveil Sprite

Flying
Whenever Nightveil Sprite attacks, surveil 1. (Look at the top card of your library. You may put it into your graveyard.)

Dromar's Charm

Choose one —
• You gain 5 life.
• Counter target spell.
• Target creature gets -2/-2 until end of turn.

Darksteel Mutation

Enchant creature
Enchanted creature is an Insect artifact creature with base power and toughness 0/1 and has indestructible, and it loses all other abilities, card types, and creature types.

Evolving Wilds

{T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Mind Unbound

At the beginning of your upkeep, put a lore counter on Mind Unbound, then draw a card for each lore counter on Mind Unbound.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Island

Deep Analysis

Target player draws two cards.
Flashback—{1}{U}, Pay 3 life. (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Azorius Guildgate

This land enters tapped.
{T}: Add {W} or {U}.

Angler Turtle

Hexproof
Creatures your opponents control attack each combat if able.

Sublime Exhalation

Undaunted (This spell costs {1} less to cast for each opponent.)
Destroy all creatures.

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Plains

Wall of Omens

Defender
When Wall of Omens enters, draw a card.

Prismatic Lens

{T}: Add {C}.
{1}, {T}: Add one mana of any color.

Ur-Golem's Eye

Dissolve

Counter target spell. Scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Fleshbag Marauder

When Fleshbag Marauder enters, each player sacrifices a creature of their choice.

Greed

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Felidar Sovereign

Vigilance (Attacking doesn't cause this creature to tap.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Honden of Cleansing Fire

At the beginning of your upkeep, you gain 2 life for each Shrine you control.

Sejiri Refuge

Sejiri Refuge enters tapped.
When Sejiri Refuge enters, you gain 1 life.
{T}: Add {W} or {U}.

Rapid Hybridization

Destroy target creature. It can't be regenerated. That creature's controller creates a 3/3 green Frog Lizard creature token.

Oloro, Ageless Ascetic

At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro, Ageless Ascetic is in the command zone, you gain 2 life.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Pacifism

Enchant creature
Enchanted creature can't attack or block.

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.