Damnation

Destroy all creatures. They can't be regenerated.

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Words of Worship

{1}: The next time you would draw a card this turn, you gain 5 life instead.

Demonic Pact

At the beginning of your upkeep, choose one that hasn't been chosen —
• Demonic Pact deals 4 damage to any target and you gain 4 life.
• Target opponent discards two cards.
• Draw two cards.
• You lose the game.

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Crumbling Necropolis

Crumbling Necropolis enters the battlefield tapped.
{T}: Add {U}, {B}, or {R}.

Chromatic Lantern

Lands you control have "{T}: Add one mana of any color."
{T}: Add one mana of any color.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Vindicate

Laboratory Maniac

If you would draw a card while your library has no cards in it, you win the game instead.

Solitary Confinement

At the beginning of your upkeep, sacrifice Solitary Confinement unless you discard a card.
Skip your draw step.
You have shroud. (You can't be the target of spells or abilities.)
Prevent all damage that would be dealt to you.

Flooded Strand

{T}, Pay 1 life, Sacrifice Flooded Strand: Search your library for a Plains or Island card, put it onto the battlefield, then shuffle.

Elixir of Immortality

{2}, {T}: You gain 5 life. Shuffle Elixir of Immortality and your graveyard into their owner's library.

Worn Powerstone

Worn Powerstone enters the battlefield tapped.
{T}: Add {C}{C}.

Scalding Tarn

{T}, Pay 1 life, Sacrifice Scalding Tarn: Search your library for an Island or Mountain card, put it onto the battlefield, then shuffle.

Enlightened Tutor

Search your library for an artifact or enchantment card, reveal it, then shuffle and put that card on top.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Glorious End

End the turn. (Exile all spells and abilities from the stack, including this card. The player whose turn it is discards down to their maximum hand size. Damage wears off, and "this turn" and "until end of turn" effects end.)
At the beginning of your next end step, you lose the game.

Soul Warden

Whenever another creature enters the battlefield, you gain 1 life.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Nomad Outpost

Nomad Outpost enters the battlefield tapped.
{T}: Add {R}, {W}, or {B}.

Temple of Enlightenment

Temple of Enlightenment enters the battlefield tapped.
When Temple of Enlightenment enters the battlefield, scry 1.
{T}: Add {W} or {U}.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Darien, King of Kjeldor

Whenever you're dealt damage, you may create that many 1/1 white Soldier creature tokens.

Slaughter Pact

Destroy target nonblack creature.
At the beginning of your next upkeep, pay {2}{B}. If you don't, you lose the game.

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Leyline of Sanctity

If Leyline of Sanctity is in your opening hand, you may begin the game with it on the battlefield.
You have hexproof. (You can't be the target of spells or abilities your opponents control.)

Darksteel Ingot

Indestructible (Effects that say "destroy" don't destroy this artifact.)
{T}: Add one mana of any color.

Disciple of Bolas

When Disciple of Bolas enters the battlefield, sacrifice another creature. You gain X life and draw X cards, where X is that creature's power.

Steam Vents

({T}: Add {U} or {R}.)
As Steam Vents enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Maze of Ith

{T}: Untap target attacking creature. Prevent all combat damage that would be dealt to and dealt by that creature this turn.

Venser's Journal

You have no maximum hand size.
At the beginning of your upkeep, you gain 1 life for each card in your hand.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Thalia's Lancers

First strike
When Thalia's Lancers enters the battlefield, you may search your library for a legendary card, reveal it, put it into your hand, then shuffle.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Mystic Monastery

Mystic Monastery enters the battlefield tapped.
{T}: Add {U}, {R}, or {W}.

City of Brass

Whenever City of Brass becomes tapped, it deals 1 damage to you.
{T}: Add one mana of any color.

Counterspell

Open the Vaults

Return all artifact and enchantment cards from all graveyards to the battlefield under their owners' control. (Auras with nothing to enchant remain in graveyards.)

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Arid Mesa

{T}, Pay 1 life, Sacrifice Arid Mesa: Search your library for a Mountain or Plains card, put it onto the battlefield, then shuffle.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Words of Waste

{1}: The next time you would draw a card this turn, each opponent discards a card instead.

Pact of the Titan

Create a 4/4 red Giant creature token.
At the beginning of your next upkeep, pay {4}{R}. If you don't, you lose the game.

Hive Mind

Whenever a player casts an instant or sorcery spell, each other player copies that spell. Each of those players may choose new targets for their copy.

Idyllic Tutor

Search your library for an enchantment card, reveal it, put it into your hand, then shuffle.

Ludevic, Necro-Alchemist

At the beginning of each player's end step, that player may draw a card if a player other than you lost life this turn.
Partner (You can have two commanders if both have partner.)

Swan Song

Counter target enchantment, instant, or sorcery spell. Its controller creates a 2/2 blue Bird creature token with flying.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Reliquary Tower

The Locust God

Flying
Whenever you draw a card, create a 1/1 blue and red Insect creature token with flying and haste.
{2}{U}{R}: Draw a card, then discard a card.
When The Locust God dies, return it to its owner's hand at the beginning of the next end step.

Final Fortune

Take an extra turn after this one. At the beginning of that turn's end step, you lose the game.

Hallowed Fountain

({T}: Add {W} or {U}.)
As Hallowed Fountain enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Temple of Deceit

Temple of Deceit enters the battlefield tapped.
When Temple of Deceit enters the battlefield, scry 1.
{T}: Add {U} or {B}.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Sacred Foundry

({T}: Add {R} or {W}.)
As Sacred Foundry enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Island

Tymna the Weaver

Lifelink
At the beginning of your postcombat main phase, you may pay X life, where X is the number of opponents that were dealt combat damage this turn. If you do, draw X cards.
Partner (You can have two commanders if both have partner.)

Nefarious Lich

If damage would be dealt to you, exile that many cards from your graveyard instead. If you can't, you lose the game.
If you would gain life, draw that many cards instead.
When Nefarious Lich leaves the battlefield, you lose the game.

Temple of Silence

Temple of Silence enters the battlefield tapped.
When Temple of Silence enters the battlefield, scry 1.
{T}: Add {W} or {B}.

Obzedat's Aid

Return target permanent card from your graveyard to the battlefield.

Arcane Lighthouse

{T}: Add {C}.
{1}, {T}: Until end of turn, creatures your opponents control lose hexproof and shroud and can't have hexproof or shroud.

Aegis Angel

Flying (This creature can't be blocked except by creatures with flying or reach.)
When Aegis Angel enters the battlefield, another target permanent gains indestructible for as long as you control Aegis Angel. (Effects that say "destroy" don't destroy it. A creature with indestructible can't be destroyed by damage.)

Last Chance

Negate

Temple of Epiphany

Temple of Epiphany enters the battlefield tapped.
When Temple of Epiphany enters the battlefield, scry 1.
{T}: Add {U} or {R}.

Intervention Pact

The next time a source of your choice would deal damage to you this turn, prevent that damage. You gain life equal to the damage prevented this way.
At the beginning of your next upkeep, pay {1}{W}{W}. If you don't, you lose the game.

Warrior's Oath

Polluted Delta

{T}, Pay 1 life, Sacrifice Polluted Delta: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Mirage Mirror

{2}: Mirage Mirror becomes a copy of target artifact, creature, enchantment, or land until end of turn.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Bloodstained Mire

{T}, Pay 1 life, Sacrifice Bloodstained Mire: Search your library for a Swamp or Mountain card, put it onto the battlefield, then shuffle.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Disallow

Counter target spell, activated ability, or triggered ability. (Mana abilities can't be targeted.)

Sol Ring

Temple of Malice

Temple of Malice enters the battlefield tapped.
When Temple of Malice enters the battlefield, scry 1.
{T}: Add {B} or {R}.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Blood Crypt

({T}: Add {B} or {R}.)
As Blood Crypt enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Diabolic Revelation

Search your library for up to X cards, put those cards into your hand, then shuffle.

Pact of Negation

Counter target spell.
At the beginning of your next upkeep, pay {3}{U}{U}. If you don't, you lose the game.

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Plains

Swamp

Soul's Attendant

Whenever another creature enters the battlefield, you may gain 1 life.

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Academy Rector

When Academy Rector dies, you may exile it. If you do, search your library for an enchantment card, put that card onto the battlefield, then shuffle.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.