Mutational Advantage

Permanents you control with counters on them gain hexproof and indestructible until end of turn. Prevent all damage that would be dealt to those permanents this turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Lumbering Megasloth

This spell costs {1} less to cast for each counter among players and permanents.
Trample
Lumbering Megasloth enters tapped.

Butch DeLoria, Tunnel Snake

Menace (This creature can't be blocked except by two or more creatures.)
Tunnel Snakes Rule! — Whenever Butch DeLoria, Tunnel Snake attacks, it gets +1/+1 until end of turn for each other Rogue and/or Snake you control.
{1}{B}: Put a menace counter on another target creature. It becomes a Rogue in addition to its other types.

Break Down

Destroy target artifact or enchantment. Create a Junk token. (It's an artifact with "{T}, Sacrifice this artifact: Exile the top card of your library. You may play that card this turn. Activate only as a sorcery.")

Rampant Growth

Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Strong, the Brutish Thespian

Ward {2}
Enrage — Whenever Strong is dealt damage, you get three rad counters and put three +1/+1 counters on Strong.
You gain life rather than lose life from radiation.

The Wise Mothman

Flying
Whenever The Wise Mothman enters or attacks, each player gets a rad counter.
Whenever one or more nonland cards are milled, put a +1/+1 counter on each of up to X target creatures, where X is the number of nonland cards milled this way.

Glowing One

Deathtouch
Whenever Glowing One deals combat damage to a player, they get four rad counters.
Whenever a player mills a nonland card, you gain 1 life.

Inspiring Call

Draw a card for each creature you control with a +1/+1 counter on it. Those creatures gain indestructible until end of turn. (Damage and effects that say "destroy" don't destroy them.)

Casualties of War

Choose one or more —
• Destroy target artifact.
• Destroy target creature.
• Destroy target enchantment.
• Destroy target land.
• Destroy target planeswalker.

Deadly Dispute

As an additional cost to cast this spell, sacrifice an artifact or creature.
Draw two cards and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Single Combat

Each player chooses a creature or planeswalker they control, then sacrifices the rest. Players can't cast creature or planeswalker spells until the end of your next turn.

Atraxa, Praetors' Voice

Flying, vigilance, deathtouch, lifelink
At the beginning of your end step, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Rampaging Yao Guai

Vigilance, trample
Rampaging Yao Guai enters with X +1/+1 counters on it.
When Rampaging Yao Guai enters, destroy any number of target artifacts and/or enchantments with total mana value X or less.

Inexorable Tide

Whenever you cast a spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Hour of Reckoning

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Destroy all nontoken creatures.

Cultivate

Search your library for up to two basic land cards, reveal those cards, put one onto the battlefield tapped and the other into your hand, then shuffle.

Cathedral Acolyte

Each creature you control with a counter on it has ward {1}. (Whenever it becomes the target of a spell or ability an opponent controls, counter it unless that player pays {1}.)
{T}: Put a +1/+1 counter on target creature that entered this turn.

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Glimmer of Genius

Scry 2, then draw two cards. You get {E}{E} (two energy counters).

Mirelurk Queen

Vigilance
When Mirelurk Queen enters, target player gets two rad counters.
Whenever one or more nonland cards are milled, draw a card, then put a +1/+1 counter on Mirelurk Queen. This ability triggers only once each turn.

Power Fist

Equipped creature has trample and "Whenever this creature deals combat damage to a player, put that many +1/+1 counters on it."
Equip {2}

Alpha Deathclaw

Menace, trample
When Alpha Deathclaw enters or becomes monstrous, destroy target permanent.
{5}{B}{G}: Monstrosity 4. (If this creature isn't monstrous, put four +1/+1 counters on it and it becomes monstrous.)

Tireless Tracker

Landfall — Whenever a land you control enters, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")
Whenever you sacrifice a Clue, put a +1/+1 counter on Tireless Tracker.

Paladin Danse, Steel Maverick

Vigilance, lifelink
Exile Paladin Danse, Steel Maverick: Each creature you control that's an artifact or Human gains indestructible until end of turn.

Harmonize

Abundant Growth

Enchant land
When Abundant Growth enters, draw a card.
Enchanted land has "{T}: Add one mana of any color."

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Vexing Radgull

Flying
Whenever Vexing Radgull deals combat damage to a player, that player gets two rad counters if they don't have any rad counters. Otherwise, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Wild Growth

Enchant land
Whenever enchanted land is tapped for mana, its controller adds an additional {G}.

Valorous Stance

Choose one —
• Target creature gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)
• Destroy target creature with toughness 4 or greater.

Struggle for Project Purity

As Struggle for Project Purity enters, choose Brotherhood or Enclave.
• Brotherhood — At the beginning of your upkeep, each opponent draws a card. You draw a card for each card drawn this way.
• Enclave — Whenever a player attacks you with one or more creatures, that player gets twice that many rad counters.

Elder Arthur Maxson

Creature tokens you control have training. (Whenever a creature token you control attacks with another creature with greater power, put a +1/+1 counter on that token.)
Blind Betrayal — Sacrifice another creature: Elder Arthur Maxson gains indestructible until end of turn.

Finality

You may put two +1/+1 counters on a creature you control. Then all creatures get -4/-4 until end of turn.

Find

Return up to two target creature cards from your graveyard to your hand.

Find // Finality

Jason Bright, Glowing Prophet

Whenever a Zombie or Mutant you control dies, if its power was different from its base power, draw a card.
Come Fly With Me — {2}, Sacrifice a creature: Put a +1/+1 counter on target creature you control. It gains flying until end of turn.

Putrefy

Destroy target artifact or creature. It can't be regenerated.

Almost Perfect

Enchant creature
Enchanted creature has base power and toughness 9/10 and has indestructible.

Farseek

Search your library for a Plains, Island, Swamp, or Mountain card, put it onto the battlefield tapped, then shuffle.

Fertile Ground

Enchant land
Whenever enchanted land is tapped for mana, its controller adds an additional one mana of any color.

Sentry Bot

Flash
This spell costs {1} less to cast for each creature attacking you.
When Sentry Bot enters, you get {E} for each creature attacking you.
At the beginning of combat on your turn, you may pay {E}{E}{E}. If you do, put a +1/+1 counter on each creature you control.

Heroic Intervention

Permanents you control gain hexproof and indestructible until end of turn.

The Master, Transcendent

When The Master, Transcendent enters, target player gets two rad counters.
{T}: Put target creature card in a graveyard that was milled this turn onto the battlefield under your control. It's a green Mutant with base power and toughness 3/3. (It loses its other colors and creature types.)

Vault 75: Middle School

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Exile all creatures with power 4 or greater.
II, III — Put a +1/+1 counter on each creature you control.

Tato Farmer

Landfall — Whenever a land you control enters, you may get two rad counters.
{T}: Put target land card in a graveyard that was milled this turn onto the battlefield under your control tapped.

Corpsejack Menace

If one or more +1/+1 counters would be put on a creature you control, twice that many +1/+1 counters are put on it instead.

Black Market

Whenever a creature dies, put a charge counter on Black Market.
At the beginning of your first main phase, add {B} for each charge counter on Black Market.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Hardened Scales

If one or more +1/+1 counters would be put on a creature you control, that many plus one +1/+1 counters are put on it instead.

Nightkin Ambusher

Ward {2} (Whenever this creature becomes the target of a spell or ability an opponent controls, counter it unless that player pays {2}.)
When Nightkin Ambusher enters, target player gets four rad counters.
Nightkin Ambusher can't be blocked as long as defending player has a rad counter.

Watchful Radstag

Evolve (Whenever a creature you control enters, if that creature has greater power or toughness than this creature, put a +1/+1 counter on this creature.)
Whenever Watchful Radstag evolves, create a token that's a copy of it.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Infesting Radroach

Flying
Infesting Radroach can't block.
Whenever Infesting Radroach deals combat damage to a player, they get that many rad counters.
Whenever an opponent mills a nonland card, if Infesting Radroach is in your graveyard, you may return it to your hand.

Bloatfly Swarm

Flying
Bloatfly Swarm enters with five +1/+1 counters on it.
If damage would be dealt to Bloatfly Swarm while it has a +1/+1 counter on it, prevent that damage, remove that many +1/+1 counters from it, then give each player a rad counter for each +1/+1 counter removed this way.

Contaminated Drink

Draw X cards, then you get half X rad counters, rounded up.

Radstorm

Storm (When you cast this spell, copy it for each spell cast before it this turn.)
Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Feral Ghoul

Menace
Whenever another creature you control dies, put a +1/+1 counter on Feral Ghoul.
When Feral Ghoul dies, each opponent gets a number of rad counters equal to its power.

Yes Man, Personal Securitron

{T}: Target opponent gains control of Yes Man, Personal Securitron. When they do, you draw two cards and put a quest counter on Yes Man. Activate only during your turn.
Wild Card — When Yes Man leaves the battlefield, its owner creates a tapped 1/1 white Soldier creature token for each quest counter on it.

Marcus, Mutant Mayor

Vigilance, trample
Whenever a creature you control deals combat damage to a player, draw a card if that creature has a +1/+1 counter on it. If it doesn't, put a +1/+1 counter on it.

Atomize

Destroy target nonland permanent. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Lethal Scheme

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Destroy target creature or planeswalker. Each creature that convoked Lethal Scheme connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on that creature.)

Vigor

Trample
If damage would be dealt to another creature you control, prevent that damage. Put a +1/+1 counter on that creature for each 1 damage prevented this way.
When Vigor is put into a graveyard from anywhere, shuffle it into its owner's library.

Branching Evolution

If one or more +1/+1 counters would be put on a creature you control, twice that many +1/+1 counters are put on that creature instead.

Well Rested

Enchant creature
Enchanted creature has "Whenever this creature becomes untapped, put two +1/+1 counters on it, then you gain 2 life and draw a card. This ability triggers only once each turn."

Agent Frank Horrigan

Trample
Agent Frank Horrigan has indestructible as long as it attacked this turn.
Whenever Agent Frank Horrigan enters or attacks, proliferate twice. (To proliferate, choose any number of permanents and/or players, then give each another counter of each kind already there.)

Battle of Hoover Dam

As Battle of Hoover Dam enters, choose NCR or Legion.
• NCR — At the beginning of your end step, return target creature card with mana value 3 or less from your graveyard to the battlefield with a finality counter on it.
• Legion — Whenever a creature you control dies, put two +1/+1 counters on target creature you control.

Guardian Project

Whenever a nontoken creature you control enters, if it doesn't have the same name as another creature you control or a creature card in your graveyard, draw a card.

Winding Constrictor

If one or more counters would be put on an artifact or creature you control, that many plus one of each of those kinds of counters are put on that permanent instead.
If you would get one or more counters, you get that many plus one of each of those kinds of counters instead.

Piper Wright, Publick Reporter

Whenever Piper Wright deals combat damage to a player, investigate that many times. (To investigate, create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")
Whenever you sacrifice a Clue, put a +1/+1 counter on target creature you control.

Colonel Autumn

Lifelink
Exploit (When this creature enters, you may sacrifice a creature.)
Other legendary creatures you control have exploit.
Whenever a creature you control exploits a creature, put a +1/+1 counter on each creature you control.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Sierra, Nuka's Biggest Fan

The Nuka-Cola Challenge — Whenever one or more creatures you control deal combat damage to a player, put a quest counter on Sierra, Nuka's Biggest Fan and create a Food token.
Whenever you sacrifice a Food, target creature you control gets +X/+X until end of turn, where X is the number of quest counters on Sierra.

Lily Bowen, Raging Grandma

Vigilance
Lily Bowen, Raging Grandma enters with two +1/+1 counters on it.
At the beginning of your upkeep, double the number of +1/+1 counters on Lily Bowen if its power is 16 or less. Otherwise, remove all but one +1/+1 counter from it, then you gain 1 life for each +1/+1 counter removed this way.