Negate

Rona, Sheoldred's Faithful

Whenever you cast an instant or sorcery spell, each opponent loses 1 life.
You may cast Rona, Sheoldred's Faithful from your graveyard by discarding two cards in addition to paying its other costs.

Experimental Augury

Look at the top three cards of your library. Put one of them into your hand and the rest on the bottom of your library in any order. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Dimir Guildgate

Dimir Guildgate enters the battlefield tapped.
{T}: Add {U} or {B}.

Arcane Melee

Instant and sorcery spells cost {2} less to cast.

Frantic Search

Draw two cards, then discard two cards. Untap up to three lands.

Octavia, Living Thesis

This spell costs {8} less to cast if you have eight or more instant and/or sorcery cards in your graveyard.
Ward {8}
Magecraft — Whenever you cast or copy an instant or sorcery spell, target creature has base power and toughness 8/8 until end of turn.

Doom Blade

Dimir Aqueduct

Dimir Aqueduct enters the battlefield tapped.
When Dimir Aqueduct enters the battlefield, return a land you control to its owner's hand.
{T}: Add {U}{B}.

Haunting Figment

Vigilance
Haunting Figment can't be blocked as long as you've cast an instant or sorcery spell this turn.

Ice Tunnel

({T}: Add {U} or {B}.)
Ice Tunnel enters the battlefield tapped.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Resculpt

Exile target artifact or creature. Its controller creates a 4/4 blue and red Elemental creature token.

Essence Scatter

Obscura Storefront

When Obscura Storefront enters the battlefield, sacrifice it. When you do, search your library for a basic Plains, Island, or Swamp card, put it onto the battlefield tapped, then shuffle and you gain 1 life.

Talrand, Sky Summoner

Whenever you cast an instant or sorcery spell, create a 2/2 blue Drake creature token with flying.

Behold the Multiverse

Scry 2, then draw two cards.
Foretell {1}{U} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Thriving Moor

Thriving Moor enters the battlefield tapped.
As Thriving Moor enters the battlefield, choose a color other than black.
{T}: Add {B} or one mana of the chosen color.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Waterfront District

Waterfront District enters the battlefield tapped.
{T}: Add {U} or {B}.
{2}{U}{B}, {T}, Sacrifice Waterfront District: Draw a card.

Voracious Reader

Prowess (Whenever you cast a noncreature spell, this creature gets +1/+1 until end of turn.)
Instant and sorcery spells you cast cost {1} less to cast.

Curious Homunculus

{T}: Add {C}. Spend this mana only to cast an instant or sorcery spell.
At the beginning of your upkeep, if there are three or more instant and/or sorcery cards in your graveyard, transform Curious Homunculus.

Curious Homunculus // Voracious Reader

Swamp

Archaeomancer

When Archaeomancer enters the battlefield, return target instant or sorcery card from your graveyard to your hand.

Memorial to Genius

Memorial to Genius enters the battlefield tapped.
{T}: Add {U}.
{4}{U}, {T}, Sacrifice Memorial to Genius: Draw two cards.

Hero's Downfall

Walk the Plank

Disfigure

Target creature gets -2/-2 until end of turn.

Thirst for Discovery

Draw three cards. Then discard two cards unless you discard a basic land card.

Temple of Deceit

Temple of Deceit enters the battlefield tapped.
When Temple of Deceit enters the battlefield, scry 1.
{T}: Add {U} or {B}.

Murmuring Mystic

Whenever you cast an instant or sorcery spell, create a 1/1 blue Bird Illusion creature token with flying.

Gale, Waterdeep Prodigy

Whenever you cast an instant or sorcery spell from your hand, you may cast up to one target card of the other type from your graveyard. If a spell cast from your graveyard this way would be put into your graveyard, exile it instead.
Choose a Background (You can have a Background as a second commander.)

Annul

Counter target artifact or enchantment spell.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Eliminate

Destroy target creature or planeswalker with mana value 3 or less.

Cosmic Epiphany

Draw cards equal to the number of instant and sorcery cards in your graveyard.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Vohar, Vodalian Desecrator

{T}: Draw a card, then discard a card. If you discarded an instant or sorcery card this way, each opponent loses 1 life and you gain 1 life.
{2}, Sacrifice Vohar, Vodalian Desecrator: You may cast target instant or sorcery card from your graveyard this turn. If that spell would be put into your graveyard, exile it instead. Activate only as a sorcery.

Evolving Wilds

{T}, Sacrifice Evolving Wilds: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Wavebreak Hippocamp

Whenever you cast your first spell during each opponent's turn, draw a card.

Ghastly Demise

Destroy target nonblack creature if its toughness is less than or equal to the number of cards in your graveyard.

Sign in Blood

Target player draws two cards and loses 2 life.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters the battlefield tapped unless you control two or more basic lands.

Radical Idea

Draw a card.
Jump-start (You may cast this card from your graveyard by discarding a card in addition to paying its other costs. Then exile this card.)

Peek

Look at target player's hand.
Draw a card.

Mocking Sprite

Flying
Instant and sorcery spells you cast cost {1} less to cast.

Darkwater Catacombs

Deathbringer Regent

Flying
When Deathbringer Regent enters the battlefield, if you cast it from your hand and there are five or more other creatures on the battlefield, destroy all other creatures.

Serum Visions

Prescient Chimera

Flying
Whenever you cast an instant or sorcery spell, scry 1. (Look at the top card of your library. You may put that card on the bottom of your library.)

Curate

Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)
Draw a card.

Tyrant's Scorn

Choose one —
• Destroy target creature with mana value 3 or less.
• Return target creature to its owner's hand.

Consider

Surveil 1. (Look at the top card of your library. You may put it into your graveyard.)
Draw a card.

Jwar Isle Refuge

Jwar Isle Refuge enters the battlefield tapped.
When Jwar Isle Refuge enters the battlefield, you gain 1 life.
{T}: Add {U} or {B}.

Disdainful Stroke

Counter target spell with mana value 4 or greater.

Academy Wall

Defender
Whenever you cast an instant or sorcery spell, you may draw a card. If you do, discard a card. This ability triggers only once each turn.

Cancel

Nymris, Oona's Trickster

Flash
Flying
Whenever you cast your first spell during each opponent's turn, look at the top two cards of your library. Put one of those cards into your hand and the other into your graveyard.

Scholar of the Ages

When Scholar of the Ages enters the battlefield, return up to two target instant and/or sorcery cards from your graveyard to your hand.

Impulse

Look at the top four cards of your library. Put one of them into your hand and the rest on the bottom of your library in any order.

Windrider Wizard

Flying
Whenever you cast an instant, sorcery, or Wizard spell, you may draw a card. If you do, discard a card.

Command Tower

Island

Dimir Signet

Snap

Return target creature to its owner's hand. Untap up to two lands.

Ravenform

Exile target artifact or creature. Its controller creates a 1/1 blue Bird creature token with flying.
Foretell {U} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Erebos's Intervention

Choose one —
• Target creature gets -X/-X until end of turn. You gain X life.
• Exile up to twice X target cards from graveyards.

Dismal Backwater

Dismal Backwater enters the battlefield tapped.
When Dismal Backwater enters the battlefield, you gain 1 life.
{T}: Add {U} or {B}.

Treasure Cruise

Delve (Each card you exile from your graveyard while casting this spell pays for {1}.)
Draw three cards.

Deliberate

Think Twice

Draw a card.
Flashback {2}{U} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Spellkeeper Weird

{2}, {T}, Sacrifice Spellkeeper Weird: Return target instant or sorcery card from your graveyard to your hand.

Tribute to Urborg

Kicker {1}{U} (You may pay an additional {1}{U} as you cast this spell.)
Target creature gets -2/-2 until end of turn. If this spell was kicked, that creature gets an additional -1/-1 until end of turn for each instant and sorcery card in your graveyard.

Sleight of Hand

Look at the top two cards of your library. Put one of them into your hand and the other on the bottom of your library.

Thought Scour

Target player mills two cards.
Draw a card.

Heartless Act

Choose one —
• Destroy target creature with no counters on it.
• Remove up to three counters from target creature.

Annihilating Glare

As an additional cost to cast this spell, pay {4} or sacrifice an artifact or creature.
Destroy target creature or planeswalker.

Creeping Tar Pit

Creeping Tar Pit enters the battlefield tapped.
{T}: Add {U} or {B}.
{1}{U}{B}: Creeping Tar Pit becomes a 3/2 blue and black Elemental creature until end of turn and can't be blocked this turn. It's still a land.

Choked Estuary

As Choked Estuary enters the battlefield, you may reveal an Island or Swamp card from your hand. If you don't, Choked Estuary enters the battlefield tapped.
{T}: Add {U} or {B}.

Epic Downfall

Exile target creature with mana value 3 or greater.

Rise from the Tides

Create a tapped 2/2 black Zombie creature token for each instant and sorcery card in your graveyard.

Murder

Tainted Isle

{T}: Add {C}.
{T}: Add {U} or {B}. Activate only if you control a Swamp.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Dimir Charm

Choose one —
• Counter target sorcery spell.
• Destroy target creature with power 2 or less.
• Look at the top three cards of target player's library. Put one back and the rest into that player's graveyard.

Trail of Evidence

Whenever you cast an instant or sorcery spell, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Scour All Possibilities

Scry 2, then draw a card.
Flashback {4}{U} (You may cast this card from your graveyard for its flashback cost. Then exile it.)