Go for the Throat

Phyrexian Vatmother

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
At the beginning of your upkeep, you get a poison counter.

Drown in the Loch

Choose one —
• Counter target spell with mana value less than or equal to the number of cards in its controller's graveyard.
• Destroy target creature with mana value less than or equal to the number of cards in its controller's graveyard.

Sygg, River Cutthroat

At the beginning of each end step, if an opponent lost 3 or more life this turn, you may draw a card. (Damage causes loss of life.)

Lord of the Pit

Flying, trample
At the beginning of your upkeep, sacrifice a creature other than Lord of the Pit. If you can't, Lord of the Pit deals 7 damage to you.

Flesh Reaver

Whenever Flesh Reaver deals damage to a creature or opponent, Flesh Reaver deals that much damage to you.

Aetherize

Return all attacking creatures to their owner's hand.

No Mercy

Whenever a creature deals damage to you, destroy it.

Run Away Together

Choose two target creatures controlled by different players. Return those creatures to their owners' hands.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Rotting Regisaur

At the beginning of your upkeep, discard a card.

Command Tower

Fateful Handoff

Draw cards equal to the mana value of target artifact or creature you control. An opponent gains control of that permanent.

Morphic Pool

Morphic Pool enters tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Drowned Catacomb

Drowned Catacomb enters tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

Evolving Wilds

{T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Phyrexian Negator

Trample
Whenever Phyrexian Negator is dealt damage, sacrifice that many permanents.

Undercity Sewers

({T}: Add {U} or {B}.)
Undercity Sewers enters tapped.
When Undercity Sewers enters, surveil 1. (Look at the top card of your library. You may put it into your graveyard.)

Wretched Anurid

Whenever another creature enters, you lose 1 life.

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Infernal Grasp

Destroy target creature. You lose 2 life.

Diplomatic Immunity

Enchant creature
Shroud (A permanent with shroud can't be the target of spells or abilities.)
Enchanted creature has shroud.

Tainted Isle

{T}: Add {C}.
{T}: Add {U} or {B}. Activate only if you control a Swamp.

Evil Eye of Orms-by-Gore

Non-Eye creatures you control can't attack.
Evil Eye of Orms-by-Gore can't be blocked except by Walls.

Island

Arcane Denial

Counter target spell. Its controller may draw up to two cards at the beginning of the next turn's upkeep.
You draw a card at the beginning of the next turn's upkeep.

Desecration Elemental

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
Whenever a player casts a spell, sacrifice a creature.

Drinker of Sorrow

Drinker of Sorrow can't block.
Whenever Drinker of Sorrow deals combat damage, sacrifice a permanent.

Thought Eater

Flying
Your maximum hand size is reduced by three.

Ebon Drake

Flying
Whenever a player casts a spell, you lose 1 life.

Despotic Scepter

{T}: Destroy target permanent you own. It can't be regenerated.

Ebonblade Reaper

Whenever Ebonblade Reaper attacks, you lose half your life, rounded up.
Whenever Ebonblade Reaper deals combat damage to a player, that player loses half their life, rounded up.
Morph {3}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Temple of Deceit

This land enters tapped.
When this land enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{T}: Add {U} or {B}.

Rust Elemental

Flying
At the beginning of your upkeep, sacrifice an artifact other than Rust Elemental. If you can't, tap Rust Elemental and you lose 4 life.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Dimir Signet

Dark Ritual

Curse of Verbosity

Enchant player
Whenever enchanted player is attacked, you draw a card. Each opponent attacking that player does the same.

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this token: Add one mana of any color.")

Abyssal Persecutor

Flying, trample
You can't win the game and your opponents can't lose the game.

Ghoulish Impetus

Enchant creature
Enchanted creature gets +1/+1, has deathtouch, and is goaded.
When enchanted creature dies, return Ghoulish Impetus to the battlefield at the beginning of the next end step.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Demonic Taskmaster

Flying
At the beginning of your upkeep, sacrifice a creature other than Demonic Taskmaster.

Swamp

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Evil Eye of Urborg

Non-Eye creatures you control can't attack.
Whenever Evil Eye of Urborg becomes blocked by a creature, destroy that creature.

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Negate

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters, you may pay 2 life. If you don't, it enters tapped.

Steel Golem

Shipwreck Marsh

Shipwreck Marsh enters tapped unless you control two or more other lands.
{T}: Add {U} or {B}.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Exchange of Words

When Exchange of Words enters, choose two target creatures. For as long as Exchange of Words remains on the battlefield, exchange the text boxes of those creatures.

Dissipation Field

Whenever a permanent deals damage to you, return it to its owner's hand.

Pongify

Destroy target creature. It can't be regenerated. Its controller creates a 3/3 green Ape creature token.

Counterspell

Reality Shift

Exile target creature. Its controller manifests the top card of their library. (That player puts the top card of their library onto the battlefield face down as a 2/2 creature. If it's a creature card, it can be turned face up any time for its mana cost.)

Taniwha

Trample
Phasing (This phases in or out before you untap during each of your untap steps. While it's phased out, it's treated as though it doesn't exist.)
At the beginning of your upkeep, all lands you control phase out. (They phase in before you untap during your next untap step.)

Greater Harvester

At the beginning of your upkeep, sacrifice a permanent.
Whenever Greater Harvester deals combat damage to a player, that player sacrifices two permanents of their choice.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Sol Ring

Reliquary Tower

Ponder

Look at the top three cards of your library, then put them back in any order. You may shuffle.
Draw a card.

Modify Memory

Exchange control of two target creatures controlled by different players. If you control neither creature, draw three cards.

Phyrexian Soulgorger

Cumulative upkeep—Sacrifice a creature. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Archfiend of the Dross

Flying
Archfiend of the Dross enters with four oil counters on it.
At the beginning of your upkeep, remove an oil counter from Archfiend of the Dross. Then if it has no oil counters on it, you lose the game.
Whenever a creature an opponent controls dies, its controller loses 2 life.

Swan Song

Counter target enchantment, instant, or sorcery spell. Its controller creates a 2/2 blue Bird creature token with flying.

Choked Estuary

As Choked Estuary enters, you may reveal an Island or Swamp card from your hand. If you don't, Choked Estuary enters tapped.
{T}: Add {U} or {B}.

Heartless Summoning

Creature spells you cast cost {2} less to cast.
Creatures you control get -1/-1.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters tapped unless you control two or more basic lands.

Wrong Turn

Target opponent gains control of target creature. (If an attacking or blocking creature changes controllers, it's removed from combat.)

Hellcarver Demon

Flying
Whenever Hellcarver Demon deals combat damage to a player, sacrifice all other permanents you control and discard your hand. Exile the top six cards of your library. You may cast any number of spells from among cards exiled this way without paying their mana costs.

Jon Irenicus, Shattered One

At the beginning of your end step, target opponent gains control of up to one target creature you control. Put two +1/+1 counters on it and tap it. It's goaded for the rest of the game and it gains "This creature can't be sacrificed." (It attacks each combat if able and attacks a player other than you if able.)
Whenever a creature you own but don't control attacks, you draw a card.