Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Drana, Liberator of Malakir

Flying, first strike
Whenever Drana, Liberator of Malakir deals combat damage to a player, put a +1/+1 counter on each attacking creature you control.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Archfiend of Depravity

Flying
At the beginning of each opponent's end step, that player chooses up to two creatures they control, then sacrifices the rest.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature of their choice and you return up to one target creature card from your graveyard to your hand.

Case of the Gorgon's Kiss

When this Case enters, destroy up to one target creature that was dealt damage this turn.
To solve — Three or more creature cards were put into graveyards from anywhere this turn. (If unsolved, solve at the beginning of your end step.)
Solved — This Case is a 4/4 Gorgon creature with deathtouch and lifelink in addition to its other types.

Swap?

Sorin Markov

+2: Sorin Markov deals 2 damage to any target and you gain 2 life.
−3: Target opponent's life total becomes 10.
−7: You control target player during that player's next turn.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Grave Pact

Whenever a creature you control dies, each other player sacrifices a creature of their choice.

Don't Have

Indulgent Aristocrat

Lifelink
{2}, Sacrifice a creature: Put a +1/+1 counter on each Vampire you control.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Leeching Lurker

Lifelink
Nightbound (If a player casts at least two spells during their own turn, it becomes day next turn.)

Curse of Leeches

Enchant player
As this permanent transforms into Curse of Leeches, attach it to a player.
At the beginning of enchanted player's upkeep, they lose 1 life and you gain 1 life.
Daybound (If a player casts no spells during their own turn, it becomes night next turn.)

Curse of Leeches // Leeching Lurker

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Kamber, the Plunderer

Partner with Laurine, the Diversion (When this creature enters, target player may put Laurine into their hand from their library, then shuffle.)
Lifelink
Whenever a creature an opponent controls dies, you gain 1 life and create a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")

Malakir Bloodwitch

Flying, protection from white
When Malakir Bloodwitch enters, each opponent loses life equal to the number of Vampires you control. You gain life equal to the life lost this way.

Captivating Vampire

Other Vampire creatures you control get +1/+1.
Tap five untapped Vampires you control: Gain control of target creature. It becomes a Vampire in addition to its other types.

Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Dark Ritual

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Nightmare's Thirst

You gain 1 life. Target creature gets -X/-X until end of turn, where X is the amount of life you gained this turn.

Thran Dynamo

No Mercy

Whenever a creature deals damage to you, destroy it.

Anowon, the Ruin Sage

At the beginning of your upkeep, each player sacrifices a non-Vampire creature of their choice.

Jet Medallion

Black spells you cast cost {1} less to cast.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Dictate of Erebos

Flash
Whenever a creature you control dies, each opponent sacrifices a creature of their choice.

Sol Ring

Veinwitch Coven

Menace
Whenever you gain life, you may pay {B}. If you do, return target creature card from your graveyard to your hand.

Vampire of the Dire Moon

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Whip of Erebos

Creatures you control have lifelink.
{2}{B}{B}, {T}: Return target creature card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step. If it would leave the battlefield, exile it instead of putting it anywhere else. Activate only as a sorcery.

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Demon's Horn

Whenever a player casts a black spell, you may gain 1 life.

Dread Presence

Whenever a Swamp you control enters, choose one —
• You draw a card and you lose 1 life.
• Dread Presence deals 2 damage to any target and you gain 2 life.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Rhystic Tutor

Unless any player pays {2}, search your library for a card, put that card into your hand, then shuffle.

Bloodtracker

Flying
{B}, Pay 2 life: Put a +1/+1 counter on Bloodtracker.
When Bloodtracker leaves the battlefield, draw a card for each +1/+1 counter on it.

Erebos's Intervention

Choose one —
• Target creature gets -X/-X until end of turn. You gain X life.
• Exile up to twice X target cards from graveyards.

Promise of Power

Choose one —
• You draw five cards and you lose 5 life.
• Create an X/X black Demon creature token with flying, where X is the number of cards in your hand.
Entwine {4} (Choose both if you pay the entwine cost.)

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Henrika, Infernal Seer

Flying, deathtouch, lifelink
{1}{B}{B}: Each creature you control with flying, deathtouch, and/or lifelink gets +1/+0 until end of turn.

Henrika Domnathi

Flying
At the beginning of combat on your turn, choose one that hasn't been chosen —
• Each player sacrifices a creature of their choice.
• You draw a card and you lose 1 life.
• Transform Henrika Domnathi.

Henrika Domnathi // Henrika, Infernal Seer

Gifted Aetherborn

Cordial Vampire

Whenever Cordial Vampire or another creature dies, put a +1/+1 counter on each Vampire you control.

Serrated Scorpion

When Serrated Scorpion dies, it deals 2 damage to each opponent and you gain 2 life.

Venser's Journal

You have no maximum hand size.
At the beginning of your upkeep, you gain 1 life for each card in your hand.

Gonti, Lord of Luxury

Deathtouch
When Gonti, Lord of Luxury enters, look at the top four cards of target opponent's library, exile one of them face down, then put the rest on the bottom of that library in a random order. You may cast that card for as long as it remains exiled, and mana of any type can be spent to cast that spell.

Pristine Talisman

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Battle at the Bridge

Improvise (Your artifacts can help cast this spell. Each artifact you tap after you're done activating mana abilities pays for {1}.)
Target creature gets -X/-X until end of turn. You gain X life.

Glasses of Urza

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Hopeless Nightmare

When Hopeless Nightmare enters, each opponent discards a card and loses 2 life.
When Hopeless Nightmare is put into a graveyard from the battlefield, scry 2.
{2}{B}: Sacrifice Hopeless Nightmare.

Radiant Fountain

When Radiant Fountain enters, you gain 2 life.
{T}: Add {C}.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Butcher of Malakir

Flying
Whenever Butcher of Malakir or another creature you control dies, each opponent sacrifices a creature of their choice.

Vampiric Link

Enchant creature
Whenever enchanted creature deals damage, you gain that much life.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Feast of Blood

Cast this spell only if you control two or more Vampires.
Destroy target creature. You gain 4 life.

Enduring Tenacity

Whenever you gain life, target opponent loses that much life.
When Enduring Tenacity dies, if it was a creature, return it to the battlefield under its owner's control. It's an enchantment. (It's not a creature.)

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Basilisk Collar

Equipped creature has deathtouch and lifelink. (Any amount of damage it deals to a creature is enough to destroy it. Damage dealt by this creature also causes you to gain that much life.)
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Elixir of Immortality

{2}, {T}: You gain 5 life. Shuffle Elixir of Immortality and your graveyard into their owner's library.

Sudden Spoiling

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Until end of turn, creatures target player controls lose all abilities and have base power and toughness 0/2.

Reaper's Talisman

Whenever equipped creature attacks, it gains deathtouch until end of turn.
Whenever equipped creature attacks alone, defending player loses 2 life and you gain 2 life.
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Palace Siege

As Palace Siege enters, choose Khans or Dragons.
• Khans — At the beginning of your upkeep, return target creature card from your graveyard to your hand.
• Dragons — At the beginning of your upkeep, each opponent loses 2 life and you gain 2 life.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Sengir, the Dark Baron

Flying
Whenever another creature dies, put two +1/+1 counters on Sengir, the Dark Baron.
Whenever another player loses the game, you gain life equal to that player's life total as the turn began.
Partner (You can have two commanders if both have partner.)

proxy

Nyx Lotus

Nyx Lotus enters tapped.
{T}: Choose a color. Add an amount of mana of that color equal to your devotion to that color. (Your devotion to a color is the number of mana symbols of that color in the mana costs of permanents you control.)

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature you control enters, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Gonti's Machinations

Whenever you lose life for the first time each turn, you get {E}. (You get an energy counter. Damage causes loss of life.)
Pay {E}{E}, Sacrifice Gonti's Machinations: Each opponent loses 3 life. You gain life equal to the life lost this way.

Trespasser's Curse

Enchant player
Whenever a creature enchanted player controls enters, that player loses 1 life and you gain 1 life.

Heraldic Banner

As this artifact enters, choose a color.
Creatures you control of the chosen color get +1/+0.
{T}: Add one mana of the chosen color.

Vampire Scrivener

Flying
Whenever you gain life during your turn, put a +1/+1 counter on Vampire Scrivener.
Whenever you lose life during your turn, put a +1/+1 counter on Vampire Scrivener.

Leech Gauntlet

Lifelink
Equipped creature has lifelink.
Reconfigure {4} ({4}: Attach to target creature you control; or unattach from a creature. Reconfigure only as a sorcery. While attached, this isn't a creature.)

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Prism Ring

As Prism Ring enters, choose a color.
Whenever you cast a spell of the chosen color, you gain 1 life.

Lord of Lineage

Flying
Other Vampire creatures you control get +2/+2.
{T}: Create a 2/2 black Vampire creature token with flying.

Bloodline Keeper

Flying
{T}: Create a 2/2 black Vampire creature token with flying.
{B}: Transform Bloodline Keeper. Activate only if you control five or more Vampires.

Bloodline Keeper // Lord of Lineage

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature of their choice.
• Each opponent sacrifices a creature token of their choice.
• Each opponent sacrifices a planeswalker of their choice.

Erebos, Bleak-Hearted

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature.
Whenever another creature you control dies, you may pay 2 life. If you do, draw a card.
{1}{B}, Sacrifice another creature: Target creature gets -2/-1 until end of turn.

Varragoth, Bloodsky Sire

Deathtouch
Boast — {1}{B}: Target player searches their library for a card, then shuffles and puts that card on top. (Activate only if this creature attacked this turn and only once each turn.)

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Midnight Banshee

Wither (This deals damage to creatures in the form of -1/-1 counters.)
At the beginning of your upkeep, put a -1/-1 counter on each nonblack creature.

Flay Essence

Exile target creature or planeswalker. You gain life equal to the number of counters on it.

Grave Titan

Deathtouch
Whenever Grave Titan enters or attacks, create two 2/2 black Zombie creature tokens.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Nullpriest of Oblivion

Kicker {3}{B} (You may pay an additional {3}{B} as you cast this spell.)
Lifelink
Menace (This creature can't be blocked except by two or more creatures.)
When this creature enters, if it was kicked, return target creature card from your graveyard to the battlefield.