Selfless Savior

Sacrifice Selfless Savior: Another target creature you control gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Chromatic Star

{1}, {T}, Sacrifice Chromatic Star: Add one mana of any color.
When Chromatic Star is put into a graveyard from the battlefield, draw a card.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Suffer the Past

Exile X target cards from target player's graveyard. For each card exiled this way, that player loses 1 life and you gain 1 life.

Fractured Powerstone

{T}: Add {C}.
{T}: Roll the planar die. Activate only as a sorcery.

Infernal Grasp

Destroy target creature. You lose 2 life.

Consuming Sepulcher

At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Tithing Blade

When Tithing Blade enters, each opponent sacrifices a creature of their choice.
Craft with creature {4}{B} ({4}{B}, Exile this artifact, Exile a creature you control or a creature card from your graveyard: Return this card transformed under its owner's control. Craft only as a sorcery.)

Tithing Blade // Consuming Sepulcher

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Liquimetal Torque

{T}: Add {C}.
{T}: Target nonland permanent becomes an artifact in addition to its other types until end of turn.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Timely Ward

You may cast Timely Ward as though it had flash if it targets a commander.
Enchant creature
Enchanted creature has indestructible.

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature of their choice, then sacrifices a land of their choice.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Teysa, Opulent Oligarch

Deathtouch
At the beginning of your end step, investigate for each opponent who lost life this turn.
Whenever a Clue you control is put into a graveyard from the battlefield, create a 1/1 white and black Spirit creature token with flying. This ability triggers only once each turn.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Cruel Celebrant

Whenever Cruel Celebrant or another creature or planeswalker you control dies, each opponent loses 1 life and you gain 1 life.

Corpse Knight

Whenever another creature you control enters, each opponent loses 1 life.

Dreg Recycler

{T}, Sacrifice an artifact or creature: Each opponent loses 1 life and you gain 1 life.

Cauldron Familiar

When Cauldron Familiar enters, each opponent loses 1 life and you gain 1 life.
Sacrifice a Food: Return Cauldron Familiar from your graveyard to the battlefield.

Paradise Mantle

Equipped creature has "{T}: Add one mana of any color."
Equip {1}

Nezumi Road Captain

Menace
Vehicles you control have menace. (They can't be blocked except by two or more creatures.)

Okiba Reckoner Raid

(As this Saga enters and after your draw step, add a lore counter.)
I, II — Each opponent loses 1 life and you gain 1 life.
III — Exile this Saga, then return it to the battlefield transformed under your control.

Okiba Reckoner Raid // Nezumi Road Captain

Scourge of the Skyclaves

Kicker {4}{B}
When you cast this spell, if it was kicked, each player loses half their life, rounded up.
Scourge of the Skyclaves's power and toughness are each equal to 20 minus the highest life total among players.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Night Market Lookout

Whenever Night Market Lookout becomes tapped, each opponent loses 1 life and you gain 1 life.

Vicious Conquistador

Whenever Vicious Conquistador attacks, each opponent loses 1 life.

Kalastria Healer

Rally — Whenever Kalastria Healer or another Ally you control enters, each opponent loses 1 life and you gain 1 life.

Darksteel Mutation

Enchant creature
Enchanted creature is an Insect artifact creature with base power and toughness 0/1 and has indestructible, and it loses all other abilities, card types, and creature types.

Mardu Shadowspear

Whenever Mardu Shadowspear attacks, each opponent loses 1 life.
Dash {1}{B} (You may cast this spell for its dash cost. If you do, it gains haste, and it's returned from the battlefield to its owner's hand at the beginning of the next end step.)

Jeweled Amulet

{1}, {T}: Put a charge counter on Jeweled Amulet. Note the type of mana spent to pay this activation cost. Activate only if there are no charge counters on Jeweled Amulet.
{T}, Remove a charge counter from Jeweled Amulet: Add one mana of Jeweled Amulet's last noted type.

Prismatic Lens

{T}: Add {C}.
{1}, {T}: Add one mana of any color.

Underworld Coinsmith

Constellation — Whenever Underworld Coinsmith or another enchantment you control enters, you gain 1 life.
{W}{B}, Pay 1 life: Each opponent loses 1 life.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Dark Ritual

Shadows of the Past

Whenever a creature dies, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{4}{B}: Each opponent loses 2 life and you gain 2 life. Activate only if there are four or more creature cards in your graveyard.

Shepherd of Rot

{T}: Each player loses 1 life for each Zombie on the battlefield.

Bond of Agony

As an additional cost to cast this spell, pay X life.
Each other player loses X life.

Go for the Throat

Rain of Filth

Until end of turn, lands you control gain "Sacrifice this land: Add {B}."

Gonti's Machinations

Whenever you lose life for the first time each turn, you get {E}. (You get an energy counter. Damage causes loss of life.)
Pay {E}{E}, Sacrifice Gonti's Machinations: Each opponent loses 3 life. You gain life equal to the life lost this way.

Hopeless Nightmare

When Hopeless Nightmare enters, each opponent discards a card and loses 2 life.
When Hopeless Nightmare is put into a graveyard from the battlefield, scry 2.
{2}{B}: Sacrifice Hopeless Nightmare.

Lead Pipe

Equipped creature gets +2/+0.
Whenever equipped creature dies, each opponent loses 1 life.
{2}, Sacrifice Lead Pipe: Draw a card.
Equip {2}

Orzhov Signet

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Everflowing Chalice

Multikicker {2} (You may pay an additional {2} any number of times as you cast this spell.)
Everflowing Chalice enters with a charge counter on it for each time it was kicked.
{T}: Add {C} for each charge counter on Everflowing Chalice.

Creeping Inn

Whenever Creeping Inn attacks, you may exile a creature card from your graveyard. If you do, each opponent loses X life and you gain X life, where X is the number of creature cards exiled with Creeping Inn.
{4}: Creeping Inn phases out.

Hostile Hostel

{T}: Add {C}.
{1}, {T}, Sacrifice a creature: Put a soul counter on Hostile Hostel. Then if there are three or more soul counters on it, remove those counters, transform it, then untap it. Activate only as a sorcery.

Hostile Hostel // Creeping Inn

Chromatic Sphere

{1}, {T}, Sacrifice Chromatic Sphere: Add one mana of any color. Draw a card.

Thornbow Archer

Whenever Thornbow Archer attacks, each opponent who doesn't control an Elf loses 1 life.

Springleaf Drum

{T}, Tap an untapped creature you control: Add one mana of any color.

Orzhov Guildmage

{2}{W}: Target player gains 1 life.
{2}{B}: Each player loses 1 life.

Putrid Warrior

Whenever Putrid Warrior deals damage, choose one —
• Each player loses 1 life.
• Each player gains 1 life.

Mother of Runes

{T}: Target creature you control gains protection from the color of your choice until end of turn.

Swamp

Sol Ring

The Irencrag

{T}: Add {C}.
Whenever a legendary creature you control enters, you may have The Irencrag become a legendary Equipment artifact named Everflame, Heroes' Legacy. If you do, it gains equip {3} and "Equipped creature gets +3/+3" and loses all other abilities.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Leechridden Swamp

({T}: Add {B}.)
Leechridden Swamp enters tapped.
{B}, {T}: Each opponent loses 1 life. Activate only if you control two or more black permanents.

Sanctum of Stone Fangs

At the beginning of your first main phase, each opponent loses X life and you gain X life, where X is the number of Shrines you control.

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Vampire Neonate

{2}, {T}: Each opponent loses 1 life and you gain 1 life.

Winds of Abandon

Exile target creature you don't control. For each creature exiled this way, its controller searches their library for a basic land card. Those players put those cards onto the battlefield tapped, then shuffle.
Overload {4}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Warlock Class

(Gain the next level as a sorcery to add its ability.)
At the beginning of your end step, if a creature died this turn, each opponent loses 1 life.
{1}{B}: Level 2
When this Class becomes level 2, look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
{6}{B}: Level 3
At the beginning of your end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Pulse Tracker

Whenever Pulse Tracker attacks, each opponent loses 1 life.

Plains

Wernog, Rider's Chaplain

When Wernog, Rider's Chaplain enters or leaves the battlefield, each opponent may investigate. Each opponent who doesn't loses 1 life. You investigate X times, where X is one plus the number of opponents who investigated this way.
Friends forever (You can have two commanders if both have friends forever.)

Tyrant's Choice

Will of the council — Starting with you, each player votes for death or torture. If death gets more votes, each opponent sacrifices a creature of their choice. If torture gets more votes or the vote is tied, each opponent loses 4 life.

Maggot Carrier

When Maggot Carrier enters, each player loses 1 life.

Blacksmith's Skill

Target permanent gains hexproof and indestructible until end of turn. If it's an artifact creature, it gets +2/+2 until end of turn.

Lampad of Death's Vigil

{1}, Sacrifice a creature: Each opponent loses 1 life and you gain 1 life.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Loran's Escape

Target artifact or creature gains hexproof and indestructible until end of turn. Scry 1.