Fallen Ferromancer

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{1}{R}, {T}: Fallen Ferromancer deals 1 damage to any target.

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Pain Magnification

Whenever an opponent is dealt 3 or more damage by a single source, that player discards a card.

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Electrickery

Electrickery deals 1 damage to target creature you don't control.
Overload {1}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Unnerve

Stabwhisker the Odious

At the beginning of each opponent's upkeep, that player loses 1 life for each card fewer than three in their hand.

Nezumi Shortfang

{1}{B}, {T}: Target opponent discards a card. Then if that player has no cards in hand, flip Nezumi Shortfang.

Nezumi Shortfang // Stabwhisker the Odious

Khorvath's Fury

For each player, choose friend or foe. Each friend discards all cards from their hand, then draws that many cards plus one. Khorvath's Fury deals damage to each foe equal to the number of cards in their hand.

Phyresis

Enchant creature
Enchanted creature has infect. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Grafted Exoskeleton

Equipped creature gets +2/+2 and has infect. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever Grafted Exoskeleton becomes unattached from a permanent, sacrifice that permanent.
Equip {2}

Magus of the Wheel

{1}{R}, {T}, Sacrifice Magus of the Wheel: Each player discards their hand, then draws seven cards.

Dragon Mage

Flying
Whenever this creature deals combat damage to a player, each player discards their hand, then draws seven cards.

Orthion, Hero of Lavabrink

{1}{R}, {T}: Create a token that's a copy of another target creature you control. It gains haste. Sacrifice it at the beginning of the next end step. Activate only as a sorcery.
{6}{R}{R}{R}, {T}: Create five tokens that are copies of another target creature you control. They gain haste. Sacrifice them at the beginning of the next end step. Activate only as a sorcery.

You Are Already Dead

Destroy target creature that was dealt damage this turn.
Draw a card.

Circle of Flame

Whenever a creature without flying attacks you or a planeswalker you control, Circle of Flame deals 1 damage to that creature.

Chain of Plasma

Chain of Plasma deals 3 damage to any target. Then that player or that permanent's controller may discard a card. If the player does, they may copy this spell and may choose a new target for that copy.

Inferno Titan

{R}: Inferno Titan gets +1/+0 until end of turn.
Whenever Inferno Titan enters or attacks, it deals 3 damage divided as you choose among one, two, or three targets.

Kroxa, Titan of Death's Hunger

When Kroxa enters, sacrifice it unless it escaped.
Whenever Kroxa enters or attacks, each opponent discards a card, then each opponent who didn't discard a nonland card this way loses 3 life.
Escape—{B}{B}{R}{R}, Exile five other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis, the Hate-Twisted deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Twinferno

Choose one —
• When you cast your next instant or sorcery spell this turn, copy that spell. You may choose new targets for the copy.
• Target creature you control gains double strike until end of turn. (It deals both first-strike and regular combat damage.)

Invoke Calamity

You may cast up to two instant and/or sorcery spells with total mana value 6 or less from your graveyard and/or hand without paying their mana costs. If those spells would be put into your graveyard, exile them instead. Exile Invoke Calamity.

Devastating Dreams

As an additional cost to cast this spell, discard X cards at random.
Each player sacrifices X lands of their choice. Devastating Dreams deals X damage to each creature.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Rakdos Signet

Fell Specter

Flying
When Fell Specter enters, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Heartless Hidetsugu

{T}: Heartless Hidetsugu deals damage to each player equal to half that player's life total, rounded down.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Cathartic Pyre

Choose one —
• Cathartic Pyre deals 3 damage to target creature or planeswalker.
• Discard up to two cards, then draw that many cards.

Oppression

Whenever a player casts a spell, that player discards a card.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Spikefield Cave

Spikefield Cave enters tapped.
{T}: Add {R}.

Spikefield Hazard

Spikefield Hazard deals 1 damage to any target. If a permanent dealt damage this way would die this turn, exile it instead.

Spikefield Hazard // Spikefield Cave

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Smoldering Marsh

({T}: Add {B} or {R}.)
Smoldering Marsh enters tapped unless you control two or more basic lands.

Fiery Inscription

When Fiery Inscription enters, the Ring tempts you.
Whenever you cast an instant or sorcery spell, Fiery Inscription deals 2 damage to each opponent.

Rankle's Prank

Choose one or more —
• Each player discards two cards.
• Each player loses 4 life.
• Each player sacrifices two creatures of their choice.

Embereth Blaze

Embereth Blaze deals 2 damage to any target. (Then exile this card. You may cast the enchantment later from exile.)

Virtue of Courage

Whenever a source you control deals noncombat damage to an opponent, you may exile that many cards from the top of your library. You may play those cards this turn.

Virtue of Courage // Embereth Blaze

Mirrodin Avenged

Rakdos's Return

Rakdos's Return deals X damage to target opponent or planeswalker. That player or that planeswalker's controller discards X cards.

Trouble

Trouble deals damage to target player equal to the number of cards in that player's hand.
Fuse (You may cast one or both halves of this card from your hand.)

Toil

Target player draws two cards and loses 2 life.
Fuse (You may cast one or both halves of this card from your hand.)

Toil // Trouble

Offer Immortality

Target creature gains deathtouch and indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Bad Deal

You draw two cards and each opponent discards two cards. Each player loses 2 life.

Mishra's Command

Choose two —
• Choose target player. They may discard up to X cards. Then they draw a card for each card discarded this way.
• This spell deals X damage to target creature.
• This spell deals X damage to target planeswalker.
• Target creature gets +X/+0 and gains haste until end of turn.

Tainted Strike

Target creature gets +1/+0 and gains infect until end of turn. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Burglar Rat

When this creature enters, each opponent discards a card.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Storm-Kiln Artist

Storm-Kiln Artist gets +1/+0 for each artifact you control.
Magecraft — Whenever you cast or copy an instant or sorcery spell, create a Treasure token.

Sulfuric Vortex

At the beginning of each player's upkeep, Sulfuric Vortex deals 2 damage to that player.
If a player would gain life, that player gains no life instead.

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad, the Grim deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Burning Inquiry

Each player draws three cards, then discards three cards at random.

Jaya, Venerated Firemage

If another red source you control would deal damage to a permanent or player, it deals that much damage plus 1 to that permanent or player instead.
−2: Jaya, Venerated Firemage deals 2 damage to any target.

Not Dead After All

Until end of turn, target creature you control gains "When this creature dies, return it to the battlefield tapped under its owner's control, then create a Wicked Role token attached to it." (Enchanted creature gets +1/+1. When this Aura is put into a graveyard, each opponent loses 1 life.)

Spiteful Visions

At the beginning of each player's draw step, that player draws an additional card.
Whenever a player draws a card, Spiteful Visions deals 1 damage to that player.

Tor Wauki the Younger

Reach, lifelink
If another source you control would deal noncombat damage to a permanent or player, it deals that much damage plus 1 to that permanent or player instead.
Whenever you cast an instant or sorcery spell, Tor Wauki the Younger deals 2 damage to any target.

Kaervek the Merciless

Whenever an opponent casts a spell, Kaervek the Merciless deals damage equal to that spell's mana value to any target.

Skull Rend

Skull Rend deals 2 damage to each opponent. Those players each discard two cards at random.

Harsh Mentor

Whenever an opponent activates an ability of an artifact, creature, or land on the battlefield, if it isn't a mana ability, Harsh Mentor deals 2 damage to that player.

Spinerock Knoll

Hideaway 4 (When this land enters, look at the top four cards of your library, exile one face down, then put the rest on the bottom in a random order.)
Spinerock Knoll enters tapped.
{T}: Add {R}.
{R}, {T}: You may play the exiled card without paying its mana cost if an opponent was dealt 7 or more damage this turn.

Blightning

Blightning deals 3 damage to target player or planeswalker. That player or that planeswalker's controller discards two cards.

Flame Spill

Flame Spill deals 4 damage to target creature. Excess damage is dealt to that creature's controller instead.

Barbed Shocker

Trample, haste
Whenever Barbed Shocker deals damage to a player, that player discards all the cards in their hand, then draws that many cards.

Battle-Rage Blessing

The Eldest Reborn

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Each opponent sacrifices a creature or planeswalker of their choice.
II — Each opponent discards a card.
III — Put target creature or planeswalker card from a graveyard onto the battlefield under your control.

Command Tower

Davriel, Rogue Shadowmage

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, Davriel, Rogue Shadowmage deals 2 damage to them.
−1: Target player discards a card.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Zoyowa Lava-Tongue

Deathtouch
At the beginning of your end step, if you descended this turn, each opponent may discard a card or sacrifice a permanent of their choice. Zoyowa Lava-Tongue deals 3 damage to each opponent who didn't. (You descended if a permanent card was put into your graveyard from anywhere.)