Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters the battlefield tapped unless you control two or more basic lands.

Authority of the Consuls

Creatures your opponents control enter the battlefield tapped.
Whenever a creature enters the battlefield under an opponent's control, you gain 1 life.

Isolated Chapel

Isolated Chapel enters the battlefield tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Venser's Journal

You have no maximum hand size.
At the beginning of your upkeep, you gain 1 life for each card in your hand.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Tempt with Treats

Create a Food token. (Then exile this card. You may cast the creature later from exile.)

Gumdrop Poisoner

Lifelink
When Gumdrop Poisoner enters the battlefield, up to one target creature gets -X/-X until end of turn, where X is the amount of life you gained this turn.

Gumdrop Poisoner // Tempt with Treats

Enlightened Tutor

Search your library for an artifact or enchantment card, reveal it, then shuffle and put that card on top.

Wedding Ring

When Wedding Ring enters the battlefield, if it was cast, target opponent creates a token that's a copy of it.
Whenever an opponent who controls an artifact named Wedding Ring draws a card during their turn, you draw a card.
Whenever an opponent who controls an artifact named Wedding Ring gains life during their turn, you gain that much life.

Windfall

Each player discards their hand, then draws cards equal to the greatest number of cards a player discarded this way.

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Idyllic Tutor

Search your library for an enchantment card, reveal it, put it into your hand, then shuffle.

Morphic Pool

Morphic Pool enters the battlefield tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Greed

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Sea of Clouds

Sea of Clouds enters the battlefield tapped unless you have two or more opponents.
{T}: Add {W} or {U}.

Celestine, the Living Saint

Flying, lifelink
Healing Tears — At the beginning of your end step, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the amount of life you gained this turn.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Grand Abolisher

During your turn, your opponents can't cast spells or activate abilities of artifacts, creatures, or enchantments.

Dovin's Veto

This spell can't be countered.
Counter target noncreature spell.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Soul's Attendant

Whenever another creature enters the battlefield, you may gain 1 life.

Decanter of Endless Water

You have no maximum hand size.
{T}: Add one mana of any color.

Swamp

Trouble in Pairs

If an opponent would begin an extra turn, that player skips that turn instead.
Whenever an opponent attacks you with two or more creatures, draws their second card each turn, or casts their second spell each turn, you draw a card.

Angel of Destiny

Flying, double strike
Whenever a creature you control deals combat damage to a player, you and that player each gain that much life.
At the beginning of your end step, if you have at least 15 life more than your starting life total, each player Angel of Destiny attacked this turn loses the game.

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Mirrormade

You may have Mirrormade enter the battlefield as a copy of any artifact or enchantment on the battlefield.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Deserted Beach

Deserted Beach enters the battlefield tapped unless you control two or more other lands.
{T}: Add {W} or {U}.

Pristine Talisman

Absorb

Demonic Tutor

Archangel of Thune

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
Whenever you gain life, put a +1/+1 counter on each creature you control.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Chromatic Lantern

Lands you control have "{T}: Add one mana of any color."
{T}: Add one mana of any color.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Resplendent Angel

Flying
At the beginning of each end step, if you gained 5 or more life this turn, create a 4/4 white Angel creature token with flying and vigilance.
{3}{W}{W}{W}: Until end of turn, Resplendent Angel gets +2/+2 and gains lifelink.

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Terramorphic Expanse

{T}, Sacrifice Terramorphic Expanse: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Sphere of Safety

Creatures can't attack you or planeswalkers you control unless their controller pays {X} for each of those creatures, where X is the number of enchantments you control.

Ajani, Strength of the Pride

+1: You gain life equal to the number of creatures you control plus the number of planeswalkers you control.
−2: Create a 2/2 white Cat Soldier creature token named Ajani's Pridemate with "Whenever you gain life, put a +1/+1 counter on Ajani's Pridemate."
0: If you have at least 15 life more than your starting life total, exile Ajani, Strength of the Pride and each artifact and creature your opponents control.

Storm Herd

Create X 1/1 white Pegasus creature tokens with flying, where X is your life total.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Will, Scion of Peace

Vigilance
{T}: Spells you cast this turn that are white and/or blue cost {X} less to cast, where X is the amount of life you gained this turn. Activate only as a sorcery.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Command Tower

Glacial Fortress

Glacial Fortress enters the battlefield tapped unless you control a Plains or an Island.
{T}: Add {W} or {U}.

Ghostly Prison

Soul Warden

Whenever another creature enters the battlefield, you gain 1 life.

Adarkar Wastes

{T}: Add {C}.
{T}: Add {W} or {U}. Adarkar Wastes deals 1 damage to you.

Evolving Wilds

{T}, Sacrifice Evolving Wilds: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Oloro, Ageless Ascetic

At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro, Ageless Ascetic is in the command zone, you gain 2 life.

Arcane Denial

Counter target spell. Its controller may draw up to two cards at the beginning of the next turn's upkeep.
You draw a card at the beginning of the next turn's upkeep.

Island

Dreamstone Hedron

{T}: Add {C}{C}{C}.
{3}, {T}, Sacrifice Dreamstone Hedron: Draw three cards.

Vault of Champions

Vault of Champions enters the battlefield tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Boon Reflection

If you would gain life, you gain twice that much life instead.

Drogskol Reaver

Flying, double strike, lifelink
Whenever you gain life, draw a card.

Talisman of Progress

{T}: Add {C}.
{T}: Add {W} or {U}. Talisman of Progress deals 1 damage to you.

Prairie Stream

({T}: Add {W} or {U}.)
Prairie Stream enters the battlefield tapped unless you control two or more basic lands.

The One Ring

Indestructible
When The One Ring enters the battlefield, if you cast it, you gain protection from everything until your next turn.
At the beginning of your upkeep, you lose 1 life for each burden counter on The One Ring.
{T}: Put a burden counter on The One Ring, then draw a card for each burden counter on The One Ring.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature and you return up to one target creature card from your graveyard to your hand.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Plains

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Counterspell

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Hallowed Fountain

({T}: Add {W} or {U}.)
As Hallowed Fountain enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Flooded Strand

{T}, Pay 1 life, Sacrifice Flooded Strand: Search your library for a Plains or Island card, put it onto the battlefield, then shuffle.

Sol Ring

Hedron Archive

{T}: Add {C}{C}.
{2}, {T}, Sacrifice Hedron Archive: Draw two cards.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.