Ashenmoor Liege

Other black creatures you control get +1/+1.
Other red creatures you control get +1/+1.
Whenever this creature becomes the target of a spell or ability an opponent controls, that player loses 4 life.

Audacious Thief

Whenever this creature attacks, you draw a card and you lose 1 life.

Cinder Pyromancer

{T}: This creature deals 1 damage to target player or planeswalker.
Whenever you cast a red spell, you may untap this creature.

Ayara, Furnace Queen

At the beginning of combat on your turn, return up to one target artifact or creature card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step.

Ayara, Widow of the Realm

{T}, Sacrifice another creature or artifact: Ayara deals X damage to target opponent or battle and you gain X life, where X is the sacrificed permanent's mana value.
{5}{R/P}: Transform Ayara. Activate only as a sorcery. ({R/P} can be paid with either {R} or 2 life.)

Ayara, Widow of the Realm // Ayara, Furnace Queen

Infectious Curse

Enchant player
Spells you cast that target enchanted player cost {1} less to cast.
At the beginning of enchanted player's upkeep, that player loses 1 life and you gain 1 life.

Accursed Witch

Spells your opponents cast that target this creature cost {1} less to cast.
When this creature dies, return it to the battlefield transformed under your control attached to target opponent.

Accursed Witch // Infectious Curse

Sign in Blood

Target player draws two cards and loses 2 life.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: This artifact deals 50 damage to any target.

Rowan, Scion of War

Menace
{T}: Spells you cast this turn that are black and/or red cost {X} less to cast, where X is the amount of life you lost this turn. Activate only as a sorcery.