Circle of Affliction

As Circle of Affliction enters, choose a color.
Whenever a source of the chosen color deals damage to you, you may pay {1}. If you do, target player loses 1 life and you gain 1 life.

Ob Nixilis of the Black Oath

+2: Each opponent loses 1 life. You gain life equal to the life lost this way.
−2: Create a 5/5 black Demon creature token with flying. You lose 2 life.
−8: You get an emblem with "{1}{B}, Sacrifice a creature: You gain X life and draw X cards, where X is the sacrificed creature's power."
Ob Nixilis of the Black Oath can be your commander.

Consuming Corruption

Consuming Corruption deals X damage to target creature or planeswalker and you gain X life, where X is the number of Swamps you control.

Death Watch

Enchant creature
When enchanted creature dies, its controller loses life equal to its power and you gain life equal to its toughness.

Needlebite Trap

If an opponent gained life this turn, you may pay {B} rather than pay this spell's mana cost.
Target player loses 5 life and you gain 5 life.

Acolyte of Aclazotz

{T}, Sacrifice another creature or artifact: Each opponent loses 1 life and you gain 1 life.

Tevesh Szat, Doom of Fools

+2: Create two 0/1 black Thrull creature tokens.
+1: You may sacrifice another creature or planeswalker. If you do, draw two cards, then draw another card if the sacrificed permanent was a commander.
−10: Gain control of all commanders. Put all commanders from the command zone onto the battlefield under your control.
Tevesh Szat, Doom of Fools can be your commander.
Partner

Dreg Recycler

{T}, Sacrifice an artifact or creature: Each opponent loses 1 life and you gain 1 life.

Sanctum Seeker

Whenever a Vampire you control attacks, each opponent loses 1 life and you gain 1 life.

Apprentice Necromancer

{B}, {T}, Sacrifice Apprentice Necromancer: Return target creature card from your graveyard to the battlefield. That creature gains haste. At the beginning of the next end step, sacrifice it.

Campaign of Vengeance

Whenever a creature you control attacks, defending player loses 1 life and you gain 1 life.

Denethor, Ruling Steward

At the beginning of your end step, if a creature died under your control this turn, create a 1/1 white Human Soldier creature token.
{2}, Sacrifice another creature: Each opponent loses 1 life and you gain 1 life.

Vampire's Kiss

Target player loses 2 life and you gain 2 life. Create two Blood tokens. (They're artifacts with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")

Underworld Coinsmith

Constellation — Whenever Underworld Coinsmith or another enchantment you control enters, you gain 1 life.
{W}{B}, Pay 1 life: Each opponent loses 1 life.

Dying Wish

Enchant creature you control
When enchanted creature dies, target player loses X life and you gain X life, where X is its power.

Dolmen Gate

Prevent all combat damage that would be dealt to attacking creatures you control.

Crowded Crypt

{T}: Add {B}.
Whenever a creature you control dies, put a corpse counter on Crowded Crypt.
{4}{B}{B}, {T}, Sacrifice Crowded Crypt: Create a 2/2 black Zombie creature token with decayed for each corpse counter on Crowded Crypt. (A creature with decayed can't block. When it attacks, sacrifice it at end of combat.)

Terrain Generator

{T}: Add {C}.
{2}, {T}: You may put a basic land card from your hand onto the battlefield tapped.

Archpriest of Shadows

Backup 1 (When this creature enters, put a +1/+1 counter on target creature. If that's another creature, it gains the following abilities until end of turn.)
Deathtouch
Whenever this creature deals combat damage to a player or battle, return target creature card from your graveyard to the battlefield.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Priest of Forgotten Gods

{T}, Sacrifice two other creatures: Any number of target players each lose 2 life and sacrifice a creature of their choice. You add {B}{B} and draw a card.

Nocturnal Feeder

Flying
When Nocturnal Feeder dies, each opponent loses 2 life and you gain 2 life.

Unfinished Business

Return target creature card from your graveyard to the battlefield, then return up to two target Aura and/or Equipment cards from your graveyard to the battlefield attached to that creature. (If the Auras can't enchant that creature, they remain in your graveyard.)

Persistent Specimen

{2}{B}: Return Persistent Specimen from your graveyard to the battlefield tapped.

Balthor the Defiled

Minion creatures get +1/+1.
{B}{B}{B}, Exile Balthor the Defiled: Each player returns all black and all red creature cards from their graveyard to the battlefield.

Scholar of Athreos

{2}{B}: Each opponent loses 1 life. You gain life equal to the life lost this way.

Ill-Gotten Gains

Exile Ill-Gotten Gains. Each player discards their hand, then returns up to three cards from their graveyard to their hand.

Commissar Severina Raine

Leading from the Front — Whenever Commissar Severina Raine attacks, each opponent loses X life, where X is the number of other attacking creatures.
Summary Execution — {2}, Sacrifice another creature: You gain 2 life and draw a card.

Buzzing Whack-a-Doodle

As Buzzing Whack-a-Doodle enters, you and an opponent each secretly choose Whack or Doodle. Then those choices are revealed. If the choices match, Buzzing Whack-a-Doodle has that ability. Otherwise, it has Buzz.
• Whack — {T}: Target player loses 2 life.
• Doodle — {T}: You gain 3 life.
• Buzz — {2}, {T}: Draw a card.

Life Insurance

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever a nontoken creature dies, you lose 1 life and create a Treasure token.

Treacherous Greed

As an additional cost to cast this spell, sacrifice a creature that dealt damage this turn.
Draw three cards. Each opponent loses 3 life and you gain 3 life.

Nurgle's Rot

Enchant creature an opponent controls
When enchanted creature dies, return Nurgle's Rot to its owner's hand and you create a 1/3 black Demon creature token named Plaguebearer of Nurgle.

Vampire Spawn

When this creature enters, each opponent loses 2 life and you gain 2 life.

Sorin the Mirthless

+1: Look at the top card of your library. You may reveal that card and put it into your hand. If you do, you lose life equal to its mana value.
−2: Create a 2/3 black Vampire creature token with flying and lifelink.
−7: Sorin the Mirthless deals 13 damage to any target. You gain 13 life.

Bloodghast

Bloodghast can't block.
Bloodghast has haste as long as an opponent has 10 or less life.
Landfall — Whenever a land you control enters, you may return Bloodghast from your graveyard to the battlefield.

Chalice of Death

Chalice of Life

{T}: You gain 1 life. Then if you have at least 10 life more than your starting life total, transform Chalice of Life.

Chalice of Life // Chalice of Death

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Agent of Masks

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Clattering Augur

Clattering Augur can't block.
When Clattering Augur enters, you draw a card and you lose 1 life.
{2}{B}{B}: Return Clattering Augur from your graveyard to your hand.

Tablet of the Guilds

As Tablet of the Guilds enters, choose two colors.
Whenever you cast a spell, if it's at least one of the chosen colors, you gain 1 life for each of the chosen colors it is.

Savra, Queen of the Golgari

Whenever you sacrifice a black creature, you may pay 2 life. If you do, each other player sacrifices a creature of their choice.
Whenever you sacrifice a green creature, you may gain 2 life.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Foul-Tongue Shriek

Target opponent loses 1 life for each attacking creature you control. You gain that much life.

Spiteful Returned

Bestow {3}{B} (If you cast this card for its bestow cost, it's an Aura spell with enchant creature. It becomes a creature again if it's not attached to a creature.)
Whenever Spiteful Returned or enchanted creature attacks, defending player loses 2 life.
Enchanted creature gets +1/+1.

Angel of Destiny

Flying, double strike
Whenever a creature you control deals combat damage to a player, you and that player each gain that much life.
At the beginning of your end step, if you have at least 15 life more than your starting life total, each player Angel of Destiny attacked this turn loses the game.

Wurm's Tooth

Whenever a player casts a green spell, you may gain 1 life.

Purphoros, God of the Forge

Indestructible
As long as your devotion to red is less than five, Purphoros isn't a creature.
Whenever another creature you control enters, Purphoros deals 2 damage to each opponent.
{2}{R}: Creatures you control get +1/+0 until end of turn.

The Meathook Massacre

When The Meathook Massacre enters, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Arrogant Outlaw

When Arrogant Outlaw enters, if an opponent lost life this turn, each opponent loses 2 life and you gain 2 life.

Sovereign's Bite

Target player loses 3 life and you gain 3 life.

Vein Ripper

Flying
Ward—Sacrifice a creature.
Whenever a creature dies, target opponent loses 2 life and you gain 2 life.

Grim Haruspex

Morph {B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)
Whenever another nontoken creature you control dies, draw a card.

Vanquisher's Banner

As Vanquisher's Banner enters, choose a creature type.
Creatures you control of the chosen type get +1/+1.
Whenever you cast a creature spell of the chosen type, draw a card.

Duskwielder

Boast — {1}: Target opponent loses 1 life and you gain 1 life. (Activate only if this creature attacked this turn and only once each turn.)

Gurgling Anointer

Flying
Whenever you draw your second card each turn, put a +1/+1 counter on Gurgling Anointer.
When Gurgling Anointer dies, return another target creature card with mana value less than or equal to Gurgling Anointer's power from your graveyard to the battlefield.

Sigarda's Aid

You may cast Aura and Equipment spells as though they had flash.
Whenever an Equipment you control enters, you may attach it to target creature you control.

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Death of a Thousand Stings

Target player loses 1 life and you gain 1 life.
At the beginning of your upkeep, if you have more cards in hand than each opponent, you may return Death of a Thousand Stings from your graveyard to your hand.

Cadira, Caller of the Small

Trample
Whenever Cadira, Caller of the Small deals combat damage to a player, for each token you control, create a 1/1 white Rabbit creature token.

Wall of Limbs

Defender (This creature can't attack.)
Whenever you gain life, put a +1/+1 counter on Wall of Limbs.
{5}{B}{B}, Sacrifice Wall of Limbs: Target player loses X life, where X is Wall of Limbs's power.

Bruna, Light of Alabaster

Flying, vigilance
Whenever Bruna, Light of Alabaster attacks or blocks, you may attach to it any number of Auras on the battlefield and you may put onto the battlefield attached to it any number of Aura cards that could enchant it from your graveyard and/or hand.

Trespasser's Curse

Enchant player
Whenever a creature enchanted player controls enters, that player loses 1 life and you gain 1 life.

Garrulous Sycophant

At the beginning of your end step, if you're the monarch, each opponent loses 1 life and you gain 1 life.

Bastion of Remembrance

When Bastion of Remembrance enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Curse of Vengeance

Enchant player
Whenever enchanted player casts a spell, put a spite counter on Curse of Vengeance.
When enchanted player loses the game, you gain X life and draw X cards, where X is the number of spite counters on Curse of Vengeance.

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Redemption Arc

Enchant creature
Enchanted creature has indestructible and is goaded. (It attacks each combat if able and attacks a player other than you if able.)
{1}{W}: Exile enchanted creature.

Malakir Bloodwitch

Flying, protection from white
When Malakir Bloodwitch enters, each opponent loses life equal to the number of Vampires you control. You gain life equal to the life lost this way.

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Tatsunari, Toad Rider

Whenever you cast an enchantment spell, if you don't control a creature named Keimi, create Keimi, a legendary 3/3 black and green Frog creature token with "Whenever you cast an enchantment spell, each opponent loses 1 life and you gain 1 life."
{1}{G/U}: Tatsunari, Toad Rider and target Frog you control can't be blocked this turn except by creatures with flying or reach.

Skymarch Bloodletter

Flying
When Skymarch Bloodletter enters, target opponent loses 1 life and you gain 1 life.

Mardu Shadowspear

Whenever Mardu Shadowspear attacks, each opponent loses 1 life.
Dash {1}{B} (You may cast this spell for its dash cost. If you do, it gains haste, and it's returned from the battlefield to its owner's hand at the beginning of the next end step.)

Mantle of the Ancients

Enchant creature you control
When Mantle of the Ancients enters, return any number of target Aura and/or Equipment cards from your graveyard to the battlefield attached to enchanted creature.
Enchanted creature gets +1/+1 for each Aura and Equipment attached to it.

Nether Traitor

Haste
Shadow (This creature can block or be blocked by only creatures with shadow.)
Whenever another creature is put into your graveyard from the battlefield, you may pay {B}. If you do, return Nether Traitor from your graveyard to the battlefield.

Palace Siege

As Palace Siege enters, choose Khans or Dragons.
• Khans — At the beginning of your upkeep, return target creature card from your graveyard to your hand.
• Dragons — At the beginning of your upkeep, each opponent loses 2 life and you gain 2 life.

Witherbloom Command

Choose two —
• Target player mills three cards, then you return a land card from your graveyard to your hand.
• Destroy target noncreature, nonland permanent with mana value 2 or less.
• Target creature gets -3/-1 until end of turn.
• Target opponent loses 2 life and you gain 2 life.

Darkness

Prevent all combat damage that would be dealt this turn.

Solid Footing

Flash
Enchant creature
Enchanted creature gets +1/+1.
As long as enchanted creature has vigilance, it assigns combat damage equal to its toughness rather than its power.

Chancellor of the Dross

You may reveal this card from your opening hand. If you do, at the beginning of the first upkeep, each opponent loses 3 life, then you gain life equal to the life lost this way.
Flying, lifelink

Skeleton Crew

Each other creature you control that's a Skeleton or Pirate gets +1/+1.
Whenever one or more creature cards leave your graveyard, create a 2/2 black Skeleton Pirate creature token. (This ability triggers only from the battlefield.)
{5}{B}: Return Skeleton Crew from your graveyard to the battlefield tapped.

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Death Cultist

Sacrifice Death Cultist: Target player loses 1 life and you gain 1 life.

Sigil of the Empty Throne

Whenever you cast an enchantment spell, create a 4/4 white Angel creature token with flying.

Sengir, the Dark Baron

Flying
Whenever another creature dies, put two +1/+1 counters on Sengir, the Dark Baron.
Whenever another player loses the game, you gain life equal to that player's life total as the turn began.
Partner (You can have two commanders if both have partner.)

Battle Screech

Create two 1/1 white Bird creature tokens with flying.
Flashback—Tap three untapped white creatures you control. (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Hell's Caretaker

{T}, Sacrifice a creature: Return target creature card from your graveyard to the battlefield. Activate only during your upkeep.

Oathsworn Vampire

Oathsworn Vampire enters tapped.
You may cast Oathsworn Vampire from your graveyard if you gained life this turn.

Oloro, Ageless Ascetic

At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro, Ageless Ascetic is in the command zone, you gain 2 life.