Decree of Annihilation

Exile all artifacts, creatures, and lands from the battlefield, all cards from all graveyards, and all cards from all hands.
Cycling {5}{R}{R} ({5}{R}{R}, Discard this card: Draw a card.)
When you cycle Decree of Annihilation, destroy all lands.

Darksteel Forge

Artifacts you control have indestructible. (Effects that say "destroy" don't destroy them. Artifact creatures with indestructible can't be destroyed by damage.)

Snakeskin Veil

Put a +1/+1 counter on target creature you control. It gains hexproof until end of turn. (It can't be the target of spells or abilities your opponents control.)

Altar of Bone

As an additional cost to cast this spell, sacrifice a creature.
Search your library for a creature card, reveal it, put it into your hand, then shuffle.

Archivist of Oghma

Flash
Whenever an opponent searches their library, you gain 1 life and draw a card.

Glaring Spotlight

Creatures your opponents control with hexproof can be the targets of spells and abilities you control as though they didn't have hexproof.
{3}, Sacrifice Glaring Spotlight: Creatures you control gain hexproof until end of turn and can't be blocked this turn.

Sigarda, Font of Blessings

Flying
Other permanents you control have hexproof.
You may look at the top card of your library any time.
You may cast Angel spells and Human spells from the top of your library.

Jokulhaups

Destroy all artifacts, creatures, and lands. They can't be regenerated.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Shadowspear

Equipped creature gets +1/+1 and has trample and lifelink.
{1}: Permanents your opponents control lose hexproof and indestructible until end of turn.
Equip {2}

Rocco, Cabaretti Caterer

When Rocco, Cabaretti Caterer enters, if you cast it, you may search your library for a creature card with mana value X or less, put it onto the battlefield, then shuffle.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Detection Tower

{T}: Add {C}.
{1}, {T}: Until end of turn, your opponents and creatures your opponents control with hexproof can be the targets of spells and abilities you control as though they didn't have hexproof.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Mana Tithe

Counter target spell unless its controller pays {1}.

Beaming Defiance

Target creature you control gets +2/+2 and gains hexproof until end of turn. (It can't be the target of spells or abilities your opponents control.)

Metropolis Reformer

Flying, vigilance
You have hexproof.
Whenever Metropolis Reformer is dealt damage, you gain that much life.

Avacyn, Angel of Hope

Flying, vigilance, indestructible
Other permanents you control have indestructible.

Privileged Position

({G/W} can be paid with either {G} or {W}.)
Other permanents you control have hexproof. (They can't be the targets of spells or abilities your opponents control.)

Trailblazer's Boots

Equipped creature has nonbasic landwalk. (It can't be blocked as long as defending player controls a nonbasic land.)
Equip {2}

Idyllic Tutor

Search your library for an enchantment card, reveal it, put it into your hand, then shuffle.

Bastion Protector

Commander creatures you control get +2/+2 and have indestructible.

Mana Confluence

{T}, Pay 1 life: Add one mana of any color.

Ravages of War

Arcane Lighthouse

{T}: Add {C}.
{1}, {T}: Until end of turn, creatures your opponents control lose hexproof and shroud and can't have hexproof or shroud.

Enlightened Tutor

Search your library for an artifact or enchantment card, reveal it, then shuffle and put that card on top.

Axgard Armory

Axgard Armory enters tapped.
{T}: Add {W}.
{1}{R}{R}{W}, {T}, Sacrifice Axgard Armory: Search your library for an Aura card and/or an Equipment card, reveal them, put them into your hand, then shuffle.

Sol Ring

Sylvan Tutor

Search your library for a creature card, reveal it, then shuffle and put that card on top.

Mana Crypt

At the beginning of your upkeep, flip a coin. If you lose the flip, Mana Crypt deals 3 damage to you.
{T}: Add {C}{C}.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Tamiyo's Safekeeping

Target permanent you control gains hexproof and indestructible until end of turn. You gain 2 life. (A permanent with hexproof and indestructible can't be the target of spells or abilities your opponents control. Damage and effects that say "destroy" don't destroy it.)

Armageddon

Worldly Tutor

Search your library for a creature card, reveal it, then shuffle and put the card on top.

Devastation

Angelic Enforcer

Flying
You have hexproof.
Angelic Enforcer's power and toughness are each equal to your life total.
Whenever Angelic Enforcer attacks, double your life total.

Enduring Angel

Flying, double strike
You have hexproof.
If your life total would be reduced to 0 or less, instead transform Enduring Angel and your life total becomes 3. Then if Enduring Angel didn't transform this way, you lose the game.

Enduring Angel // Angelic Enforcer

Blossoming Defense

Target creature you control gets +2/+2 and gains hexproof until end of turn.

Obliterate

This spell can't be countered.
Destroy all artifacts, creatures, and lands. They can't be regenerated.

Terra Eternal

Leyline of Sanctity

If Leyline of Sanctity is in your opening hand, you may begin the game with it on the battlefield.
You have hexproof. (You can't be the target of spells or abilities your opponents control.)