Fruit of Tizerus

Target player loses 2 life.
Escape—{3}{B}, Exile three other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Each player loses a third of their life, then discards a third of the cards in their hand, then sacrifices a third of the creatures they control of their choice, then sacrifices a third of the lands they control of their choice. Round up each time.

Malicious Eclipse

All creatures get -2/-2 until end of turn. If a creature an opponent controls would die this turn, exile it instead.

Boarded Window

Creatures attacking you get -1/-0.
At the beginning of each end step, if you were dealt 4 or more damage this turn, exile this artifact.

Destroy the Evidence

Destroy target land. Its controller reveals cards from the top of their library until they reveal a land card, then puts those cards into their graveyard.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Elixir of Immortality

{2}, {T}: You gain 5 life. Shuffle this artifact and your graveyard into their owner's library.

Gifted Aetherborn

Desert of the Glorified

This land enters tapped.
{T}: Add {B}.
Cycling {1}{B} ({1}{B}, Discard this card: Draw a card.)

Hopeless Nightmare

When this enchantment enters, each opponent discards a card and loses 2 life.
When this enchantment is put into a graveyard from the battlefield, scry 2.
{2}{B}: Sacrifice this enchantment.

Lash of the Balrog

As an additional cost to cast this spell, sacrifice a creature or pay {4}.
Destroy target creature.

Live Fast

You draw two cards, lose 2 life, and get {E}{E} (two energy counters).

Funeral Rites

You draw two cards, lose 2 life, then mill two cards.

Alms of the Vein

Target opponent loses 3 life and you gain 3 life.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Temple of the Dead

(Transforms from Aclazotz, Deepest Betrayal.)
{T}: Add {B}.
{2}{B}, {T}: Transform this land. Activate only if a player has one or fewer cards in hand and only as a sorcery.

Aclazotz, Deepest Betrayal

Flying, lifelink
Whenever Aclazotz attacks, each opponent discards a card. For each opponent who can't, you draw a card.
Whenever an opponent discards a land card, create a 1/1 black Bat creature token with flying.
When Aclazotz dies, return it to the battlefield tapped and transformed under its owner's control.

Aclazotz, Deepest Betrayal // Temple of the Dead

Stinging Cave Crawler

Deathtouch
Descend 4 — Whenever this creature attacks, if there are four or more permanent cards in your graveyard, you draw a card and you lose 1 life.

Witch's Cauldron

{1}{B}, {T}, Sacrifice a creature: You gain 1 life and draw a card.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Blightspeaker

{T}: Target player loses 1 life.
{4}, {T}: Search your library for a Rebel permanent card with mana value 3 or less, put it onto the battlefield, then shuffle.

Mephitic Draught

When this artifact enters or is put into a graveyard from the battlefield, you draw a card and you lose 1 life.

Swamp

Reckoner's Bargain

As an additional cost to cast this spell, sacrifice an artifact or creature.
You gain life equal to the sacrificed permanent's mana value. Draw two cards.

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature of their choice.
• Each opponent sacrifices a creature token of their choice.
• Each opponent sacrifices a planeswalker of their choice.

Lim-Dûl's Hex

At the beginning of your upkeep, for each player, this enchantment deals 1 damage to that player unless they pay {B} or {3}.

Vengeful Reaper

Flying, deathtouch, haste
Foretell {1}{B} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Throne of Bone

Whenever a player casts a black spell, you may pay {1}. If you do, you gain 1 life.

Insatiable Hemophage

Mutate {2}{B} (If you cast this spell for its mutate cost, put it over or under target non-Human creature you own. They mutate into the creature on top plus all abilities from under it.)
Deathtouch
Whenever this creature mutates, each opponent loses X life and you gain X life, where X is the number of times this creature has mutated.

Demonic Gifts

Until end of turn, target creature gets +2/+0 and gains "When this creature dies, return it to the battlefield under its owner's control."

Absorb Vis

Target player loses 4 life and you gain 4 life.
Basic landcycling {1}{B} ({1}{B}, Discard this card: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.)

Sheoldred's Headcleaver

Menace
Toxic 2 (Players dealt combat damage by this creature also get two poison counters.)

Demon's Due

Scry 2, then draw two cards. You lose 2 life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Infernal Pet

Whenever you cast your second spell each turn, put a +1/+1 counter on this creature and it gains flying until end of turn.

Skull Raid

Target opponent discards two cards. If fewer than two cards were discarded this way, you draw cards equal to the difference.
Foretell {1}{B} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Skirsdag Supplicant

{B}, {T}, Discard a card: Each player loses 2 life.

Nirkana Assassin

Whenever you gain life, this creature gains deathtouch until end of turn. (Any amount of damage it deals to a creature is enough to destroy it.)

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

The Immortal Sun

Players can't activate planeswalkers' loyalty abilities.
At the beginning of your draw step, draw an additional card.
Spells you cast cost {1} less to cast.
Creatures you control get +1/+1.

Dark Tutelage

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Underhanded Designs

Whenever an artifact you control enters, you may pay {1}. If you do, each opponent loses 1 life and you gain 1 life.
{1}{B}, Sacrifice this enchantment: Destroy target creature. Activate only if you control two or more artifacts.

Tavern Swindler

{T}, Pay 3 life: Flip a coin. If you win the flip, you gain 6 life.

Feed the Serpent

Rowan's Grim Search

Bargain (You may sacrifice an artifact, enchantment, or token as you cast this spell.)
If this spell was bargained, look at the top four cards of your library, then put up to two of them back on top of your library in any order and the rest into your graveyard.
You draw two cards and you lose 2 life.

Agent of the Iron Throne

Commander creatures you own have "Whenever an artifact or creature you control is put into a graveyard from the battlefield, each opponent loses 1 life."

Gloom Sower

Whenever this creature becomes blocked by a creature, that creature's controller loses 2 life and you gain 2 life.

Mind Rot

Consuming Sepulcher

At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Tithing Blade

When this artifact enters, each opponent sacrifices a creature of their choice.
Craft with creature {4}{B} ({4}{B}, Exile this artifact, Exile a creature you control or a creature card from your graveyard: Return this card transformed under its owner's control. Craft only as a sorcery.)

Tithing Blade // Consuming Sepulcher

Altar's Reap

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Serrated Scorpion

When this creature dies, it deals 2 damage to each opponent and you gain 2 life.

Armageddon Clock

At the beginning of your upkeep, put a doom counter on this artifact.
At the beginning of your draw step, this artifact deals damage equal to the number of doom counters on it to each player.
{4}: Remove a doom counter from this artifact. Any player may activate this ability but only during any upkeep step.

Foreboding Fruit

Target player draws two cards and loses 2 life.
Adamant — If at least three black mana was spent to cast this spell, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")

Lampad of Death's Vigil

{1}, Sacrifice a creature: Each opponent loses 1 life and you gain 1 life.

Orcish Bowmasters

Flash
When this creature enters and whenever an opponent draws a card except the first one they draw in each of their draw steps, this creature deals 1 damage to any target. Then amass Orcs 1.

Demon's Grasp

Target creature gets -5/-5 until end of turn.

Eradicator Valkyrie

Flying, lifelink, hexproof from planeswalkers
Boast — {1}{B}, Sacrifice a creature: Each opponent sacrifices a creature or planeswalker. (Activate only if this creature attacked this turn and only once each turn.)

Soul-Guide Lantern

When this artifact enters, exile target card from a graveyard.
{T}, Sacrifice this artifact: Exile each opponent's graveyard.
{1}, {T}, Sacrifice this artifact: Draw a card.

Teferi's Puzzle Box

At the beginning of each player's draw step, that player puts the cards in their hand on the bottom of their library in any order, then draws that many cards.

Morbid Hunger

Morbid Hunger deals 3 damage to any target. You gain 3 life.
Flashback {7}{B}{B} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Rush of Vitality

Target creature gets +1/+0 and gains lifelink and indestructible until end of turn. (Damage dealt by that creature also causes its controller to gain that much life, and it can't be destroyed by damage or effects that say "destroy.")

The Tomb of Aclazotz

(Transforms from Tarrian's Journal.)
{T}: Add {B}.
{T}: You may cast a creature spell from your graveyard this turn. If you do, it enters with a finality counter on it and is a Vampire in addition to its other types. (If a creature with a finality counter on it would die, exile it instead.)

Tarrian's Journal

{T}, Sacrifice another artifact or creature: Draw a card. Activate only as a sorcery.
{2}, {T}, Discard your hand: Transform Tarrian's Journal.

Tarrian's Journal // The Tomb of Aclazotz

Sugar Rush

Target creature gets +3/+0 until end of turn.
Draw a card.

Douse in Gloom

Douse in Gloom deals 2 damage to target creature and you gain 2 life.

Night Market Lookout

Whenever this creature becomes tapped, each opponent loses 1 life and you gain 1 life.

Black Vise

As this artifact enters, choose an opponent.
At the beginning of the chosen player's upkeep, this artifact deals X damage to that player, where X is the number of cards in their hand minus 4.

Diamond Mare

As this creature enters, choose a color.
Whenever you cast a spell of the chosen color, you gain 1 life.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Phyrexian Gargantua

When this creature enters, you draw two cards and you lose 2 life.

Sovereign's Bite

Target player loses 3 life and you gain 3 life.

Profane Memento

Whenever a creature card is put into an opponent's graveyard from anywhere, you gain 1 life.