Laboratory Maniac

If you would draw a card while your library has no cards in it, you win the game instead.

Expedition Map

{2}, {T}, Sacrifice Expedition Map: Search your library for a land card, reveal it, put it into your hand, then shuffle.

Urza's Saga

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Urza's Saga gains "{T}: Add {C}."
II — Urza's Saga gains "{2}, {T}: Create a 0/0 colorless Construct artifact creature token with 'This creature gets +1/+1 for each artifact you control.'"
III — Search your library for an artifact card with mana cost {0} or {1}, put it onto the battlefield, then shuffle.

Ensnaring Bridge

Creatures with power greater than the number of cards in your hand can't attack.

The One Ring

Indestructible
When The One Ring enters, if you cast it, you gain protection from everything until your next turn.
At the beginning of your upkeep, you lose 1 life for each burden counter on The One Ring.
{T}: Put a burden counter on The One Ring, then draw a card for each burden counter on The One Ring.

Ancient Stirrings

Look at the top five cards of your library. You may reveal a colorless card from among them and put it into your hand. Then put the rest on the bottom of your library in any order.

Shadowspear

Equipped creature gets +1/+1 and has trample and lifelink.
{1}: Permanents your opponents control lose hexproof and indestructible until end of turn.
Equip {2}

Manifold Key

{1}, {T}: Untap another target artifact.
{3}, {T}: Target creature can't be blocked this turn.

Minamo, School at Water's Edge

{T}: Add {U}.
{U}, {T}: Untap target legendary permanent.

Sunken Citadel

Sunken Citadel enters tapped. As it enters, choose a color.
{T}: Add one mana of the chosen color.
{T}: Add two mana of the chosen color. Spend this mana only to activate abilities of land sources.

Locus of Enlightenment

Locus of Enlightenment has each activated ability of the exiled cards used to craft it. You may activate each of those abilities only once each turn.
Whenever you activate an ability that isn't a mana ability, copy it. You may choose new targets for the copy.

The Enigma Jewel

The Enigma Jewel enters tapped.
{T}: Add {C}{C}. Spend this mana only to activate abilities.
Craft with four or more nonlands with activated abilities {8}{U} ({8}{U}, Exile this artifact, Exile the four or more from among other permanents you control and/or cards in your graveyard: Return this card transformed under its owner's control. Craft only as a sorcery.)

The Enigma Jewel // Locus of Enlightenment

Breeding Pool

({T}: Add {G} or {U}.)
As Breeding Pool enters, you may pay 2 life. If you don't, it enters tapped.

Defense Grid

Each spell costs {3} more to cast except during its controller's turn.

Aether Spellbomb

{U}, Sacrifice Aether Spellbomb: Return target creature to its owner's hand.
{1}, Sacrifice Aether Spellbomb: Draw a card.

Flusterstorm

Counter target instant or sorcery spell unless its controller pays {1}.
Storm (When you cast this spell, copy it for each spell cast before it this turn. You may choose new targets for the copies.)

Relic of Progenitus

{T}: Target player exiles a card from their graveyard.
{1}, Exile Relic of Progenitus: Exile all graveyards. Draw a card.

Pithing Needle

As Pithing Needle enters, choose a card name.
Activated abilities of sources with the chosen name can't be activated unless they're mana abilities.

Whir of Invention

Improvise (Your artifacts can help cast this spell. Each artifact you tap after you're done activating mana abilities pays for {1}.)
Search your library for an artifact card with mana value X or less, put it onto the battlefield, then shuffle.

Stone of Erech

If a creature an opponent controls would die, exile it instead.
{2}, {T}, Sacrifice Stone of Erech: Exile target player's graveyard. Draw a card.

Island

Simic Signet

Flooded Grove

{T}: Add {C}.
{G/U}, {T}: Add {G}{G}, {G}{U}, or {U}{U}.

Izzet Signet

Psychic Overload

Enchant permanent
When Psychic Overload enters, tap enchanted permanent.
Enchanted permanent doesn't untap during its controller's untap step.
Enchanted permanent has "Discard two artifact cards: Untap this permanent."

Dimir Signet

Botanical Sanctum

Botanical Sanctum enters tapped unless you control two or fewer other lands.
{T}: Add {G} or {U}.