Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Selenia, Dark Angel

Flying
Pay 2 life: Return Selenia, Dark Angel to its owner's hand.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Fetid Heath

{T}: Add {C}.
{W/B}, {T}: Add {W}{W}, {W}{B}, or {B}{B}.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Hedron Archive

{T}: Add {C}{C}.
{2}, {T}, Sacrifice this artifact: Draw two cards.

Dawn Charm

Choose one —
• Prevent all combat damage that would be dealt this turn.
• Regenerate target creature.
• Counter target spell that targets you.

False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Planar Collapse

At the beginning of your upkeep, if there are four or more creatures on the battlefield, sacrifice Planar Collapse and destroy all creatures. They can't be regenerated.

Magus of the Mirror

{T}, Sacrifice Magus of the Mirror: Exchange life totals with target opponent. Activate only during your upkeep.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Greater Auramancy

Other enchantments you control have shroud. (A permanent with shroud can't be the target of spells or abilities.)
Enchanted creatures you control have shroud.

Greed

Solemnity

Players can't get counters.
Counters can't be put on artifacts, creatures, enchantments, or lands.

Necrologia

Cast this spell only during your end step.
As an additional cost to cast this spell, pay X life.
Draw X cards.

Damnation

Destroy all creatures. They can't be regenerated.

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Vindicate

Idyllic Tutor

Search your library for an enchantment card, reveal it, put it into your hand, then shuffle.

Sensei's Divining Top

{1}: Look at the top three cards of your library, then put them back in any order.
{T}: Draw a card, then put Sensei's Divining Top on top of its owner's library.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Leyline of Sanctity

If Leyline of Sanctity is in your opening hand, you may begin the game with it on the battlefield.
You have hexproof. (You can't be the target of spells or abilities your opponents control.)

Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Replenish

Return all enchantment cards from your graveyard to the battlefield. (Auras with nothing to enchant remain in your graveyard.)

Wrath of God

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Exquisite Archangel

Flying
If you would lose the game, instead exile Exquisite Archangel and your life total becomes equal to your starting life total.

Temple of Silence

This land enters tapped.
When this land enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{T}: Add {W} or {B}.

Temple of Aclazotz

(Transforms from Arguel's Blood Fast.)
{T}: Add {B}.
{T}, Sacrifice a creature: You gain life equal to the sacrificed creature's toughness.

Arguel's Blood Fast

{1}{B}, Pay 2 life: Draw a card.
At the beginning of your upkeep, if you have 5 or less life, you may transform Arguel's Blood Fast.

Arguel's Blood Fast // Temple of Aclazotz

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Darkness

Prevent all combat damage that would be dealt this turn.

Gilded Lotus

Utter End

Maze of Ith

{T}: Untap target attacking creature. Prevent all combat damage that would be dealt to and dealt by that creature this turn.

Isochron Scepter

Imprint — When Isochron Scepter enters, you may exile an instant card with mana value 2 or less from your hand.
{2}, {T}: You may copy the exiled card. If you do, you may cast the copy without paying its mana cost.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Tragic Arrogance

For each player, you choose from among the permanents that player controls an artifact, a creature, an enchantment, and a planeswalker. Then each player sacrifices all other nonland permanents they control.

Academy Rector

When Academy Rector dies, you may exile it. If you do, search your library for an enchantment card, put that card onto the battlefield, then shuffle.

Orzhov Basilica

Orzhov Basilica enters tapped.
When Orzhov Basilica enters, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Sol Ring

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Season of the Witch

At the beginning of your upkeep, sacrifice Season of the Witch unless you pay 2 life.
At the beginning of the end step, destroy all untapped creatures that didn't attack this turn, except for creatures that couldn't attack.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Resolute Archangel

Flying
When Resolute Archangel enters, if your life total is less than your starting life total, it becomes equal to your starting life total.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Gideon of the Trials

+1: Until your next turn, prevent all damage target permanent would deal.
0: Until end of turn, Gideon of the Trials becomes a 4/4 Human Soldier creature with indestructible that's still a planeswalker. Prevent all damage that would be dealt to him this turn.
0: You get an emblem with "As long as you control a Gideon planeswalker, you can't lose the game and your opponents can't win the game."

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Ancient Tomb

{T}: Add {C}{C}. Ancient Tomb deals 2 damage to you.

Boseiju, Who Shelters All

Boseiju, Who Shelters All enters tapped.
{T}, Pay 2 life: Add {C}. If that mana is spent on an instant or sorcery spell, that spell can't be countered.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Mirror Universe

{T}, Sacrifice Mirror Universe: Exchange life totals with target opponent. Activate only during your upkeep.

Angel of Grace

Flash
Flying
When Angel of Grace enters, until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.
{4}{W}{W}, Exile Angel of Grace from your graveyard: Your life total becomes 10.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Reliquary Tower

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Disenchant

Pristine Talisman

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Enlightened Tutor

Search your library for an artifact or enchantment card, reveal it, then shuffle and put that card on top.

Rest in Peace

When Rest in Peace enters, exile all graveyards.
If a card or token would be put into a graveyard from anywhere, exile it instead.

Silence

Your opponents can't cast spells this turn.

Near-Death Experience

At the beginning of your upkeep, if you have exactly 1 life, you win the game.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Triskaidekaphobia

At the beginning of your upkeep, choose one —
• Each player with exactly 13 life loses the game, then each player gains 1 life.
• Each player with exactly 13 life loses the game, then each player loses 1 life.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters, you may pay 2 life. If you don't, it enters tapped.

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Angelsong

Prevent all combat damage that would be dealt this turn.
Cycling {2} ({2}, Discard this card: Draw a card.)

Snow-Covered Plains

Return to Dust

Exile target artifact or enchantment. If you cast this spell during your main phase, you may exile up to one other target artifact or enchantment.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Platinum Angel

Flying
You can't lose the game and your opponents can't win the game.

Oketra's Last Mercy

Your life total becomes equal to your starting life total. Lands you control don't untap during your next untap step.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Orzhov Guildgate

This land enters tapped.
{T}: Add {W} or {B}.

Hatred

As an additional cost to cast this spell, pay X life.
Target creature gets +X/+0 until end of turn.

Mortify

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)

Glacial Chasm

Cumulative upkeep—Pay 2 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
When Glacial Chasm enters, sacrifice a land.
Creatures you control can't attack.
Prevent all damage that would be dealt to you.

Rebuff the Wicked

Counter target spell that targets a permanent you control.

Aura of Silence

Artifact and enchantment spells your opponents cast cost {2} more to cast.
Sacrifice Aura of Silence: Destroy target artifact or enchantment.

Liliana of the Dark Realms

+1: Search your library for a Swamp card, reveal it, put it into your hand, then shuffle.
−3: Target creature gets +X/+X or -X/-X until end of turn, where X is the number of Swamps you control.
−6: You get an emblem with "Swamps you control have '{T}: Add {B}{B}{B}{B}.'"

Sphere of Safety

Creatures can't attack you or planeswalkers you control unless their controller pays {X} for each of those creatures, where X is the number of enchantments you control.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Snow-Covered Swamp

Lich

As Lich enters, you lose life equal to your life total.
You don't lose the game for having 0 or less life.
If you would gain life, draw that many cards instead.
Whenever you're dealt damage, sacrifice that many nontoken permanents. If you can't, you lose the game.
When Lich is put into a graveyard from the battlefield, you lose the game.