Descent into Avernus

At the beginning of your upkeep, put two descent counters on Descent into Avernus. Then each player creates X Treasure tokens and Descent into Avernus deals X damage to each player, where X is the number of descent counters on Descent into Avernus.

Their Number Is Legion

Create X tapped 2/2 black Necron Warrior artifact creature tokens, then you gain life equal to the number of artifacts you control. Exile Their Number Is Legion.
You may cast Their Number Is Legion from your graveyard.

Agadeem, the Undercrypt

As Agadeem, the Undercrypt enters the battlefield, you may pay 3 life. If you don't, it enters the battlefield tapped.
{T}: Add {B}.

Agadeem's Awakening

Return from your graveyard to the battlefield any number of target creature cards that each have a different mana value X or less.

Agadeem's Awakening // Agadeem, the Undercrypt

Mana Flare

Whenever a player taps a land for mana, that player adds one mana of any type that land produced.

Crushing Disappointment

Each player loses 2 life. You draw two cards.

Greed

Pact Weapon

As long as Pact Weapon is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Bloodgift Demon

Flying
At the beginning of your upkeep, target player draws a card and loses 1 life.

Blood Pact

Target player draws two cards and loses 2 life.

Dark Tutelage

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters the battlefield, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Dread Presence

Whenever a Swamp enters the battlefield under your control, choose one —
• You draw a card and you lose 1 life.
• Dread Presence deals 2 damage to any target and you gain 2 life.

Palace Siege

As Palace Siege enters the battlefield, choose Khans or Dragons.
• Khans — At the beginning of your upkeep, return target creature card from your graveyard to your hand.
• Dragons — At the beginning of your upkeep, each opponent loses 2 life and you gain 2 life.

Commune with Lava

Exile the top X cards of your library. Until the end of your next turn, you may play those cards.

Mountain

Soul Channeling

Enchant creature
Pay 2 life: Regenerate enchanted creature.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Night's Whisper

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Expedition Map

{2}, {T}, Sacrifice Expedition Map: Search your library for a land card, reveal it, put it into your hand, then shuffle.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Doom Whisperer

Flying, trample
Pay 2 life: Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Dread Summons

Each player mills X cards. For each creature card put into a graveyard this way, you create a tapped 2/2 black Zombie creature token.

Sol Ring

Comet Storm

Multikicker {1} (You may pay an additional {1} any number of times as you cast this spell.)
Choose any target, then choose another target for each time this spell was kicked. Comet Storm deals X damage to each of them.

Defiler of Instinct

First strike
As an additional cost to cast red permanent spells, you may pay 2 life. Those spells cost {R} less to cast if you paid life this way. This effect reduces only the amount of red mana you pay.
Whenever you cast a red permanent spell, Defiler of Instinct deals 1 damage to any target.

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Infernal Sovereign

Flying, trample
Skip your draw step.
Whenever you play a land or cast a spell, you draw a card and you lose 1 life.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Priest of the Blood Rite

When Priest of the Blood Rite enters the battlefield, create a 5/5 black Demon creature token with flying.
At the beginning of your upkeep, you lose 2 life.

From Under the Floorboards

Madness {X}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)
Create three tapped 2/2 black Zombie creature tokens and you gain 3 life. If this spell's madness cost was paid, instead create X of those tokens and you gain X life.

Fell Stinger

Deathtouch
Exploit (When this creature enters the battlefield, you may sacrifice a creature.)
When Fell Stinger exploits a creature, target player draws two cards and loses 2 life.

Rowan's Grim Search

Bargain (You may sacrifice an artifact, enchantment, or token as you cast this spell.)
If this spell was bargained, look at the top four cards of your library, then put up to two of them back on top of your library in any order and the rest into your graveyard.
You draw two cards and you lose 2 life.

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Sign in Blood

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Swamp

Banefire

Banefire deals X damage to any target.
If X is 5 or more, this spell can't be countered and the damage can't be prevented.

Damnable Pact

Target player draws X cards and loses X life.

Pointed Discussion

You draw two cards, lose 2 life, then create a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")

Increasing Ambition

Search your library for a card and put that card into your hand. If this spell was cast from a graveyard, instead search your library for two cards and put those cards into your hand. Then shuffle.
Flashback {7}{B} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Lord of the Forsaken

Flying, trample
{B}, Sacrifice another creature: Target player mills three cards.
Pay 1 life: Add {C}. Spend this mana only to cast a spell from your graveyard.

Phyrexian Rager

When Phyrexian Rager enters the battlefield, you draw a card and you lose 1 life.

Song of Totentanz

Create X 1/1 black Rat creature tokens with "This creature can't block." Creatures you control gain haste until end of turn.

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Rowan, Scion of War

Menace
{T}: Spells you cast this turn that are black and/or red cost {X} less to cast, where X is the amount of life you lost this turn. Activate only as a sorcery.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Bond of Agony

As an additional cost to cast this spell, pay X life.
Each other player loses X life.

Jaya's Immolating Inferno

(You may cast a legendary sorcery only if you control a legendary creature or planeswalker.)
Jaya's Immolating Inferno deals X damage to each of up to three targets.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Underworld Breach

Each nonland card in your graveyard has escape. The escape cost is equal to the card's mana cost plus exile three other cards from your graveyard. (You may cast cards from your graveyard for their escape cost.)
At the beginning of the end step, sacrifice Underworld Breach.

Starving Revenant

When Starving Revenant enters the battlefield, surveil 2. Then for each card you put on top of your library, you draw a card and you lose 3 life.
Descend 8 — Whenever you draw a card, if there are eight or more permanent cards in your graveyard, target opponent loses 1 life and you gain 1 life.

Priest of Gix

When Priest of Gix enters the battlefield, add {B}{B}{B}.

Gruesome Realization

Choose one —
• You draw two cards and you lose 2 life.
• Creatures your opponents control get -1/-1 until end of turn.

Havoc Festival

Players can't gain life.
At the beginning of each player's upkeep, that player loses half their life, rounded up.

Priest of Urabrask

When Priest of Urabrask enters the battlefield, add {R}{R}{R}.

Earthquake

Earthquake deals X damage to each creature without flying and each player.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Spawn of Mayhem

Spectacle {1}{B}{B} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
Flying, trample
At the beginning of your upkeep, Spawn of Mayhem deals 1 damage to each player. Then if you have 10 or less life, put a +1/+1 counter on Spawn of Mayhem.

Veinwitch Coven

Menace
Whenever you gain life, you may pay {B}. If you do, return target creature card from your graveyard to your hand.

Ambition's Cost

You draw three cards and you lose 3 life.

Apex of Power

Exile the top seven cards of your library. Until end of turn, you may cast spells from among them.
If this spell was cast from your hand, add ten mana of any one color.

Defiler of Flesh

Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.

Tavern Swindler

{T}, Pay 3 life: Flip a coin. If you win the flip, you gain 6 life.

Blood Celebrant

{B}, Pay 1 life: Add one mana of any color.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Ancient Craving

Marshland Bloodcaster

Flying
{1}{B}, {T}: Rather than pay the mana cost of the next spell you cast this turn, you may pay life equal to that spell's mana value.

Dire Fleet Ravager

Menace, deathtouch
When Dire Fleet Ravager enters the battlefield, each player loses a third of their life, rounded up.