Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Defiler of Instinct

First strike
As an additional cost to cast red permanent spells, you may pay 2 life. Those spells cost {R} less to cast if you paid life this way. This effect reduces only the amount of red mana you pay.
Whenever you cast a red permanent spell, Defiler of Instinct deals 1 damage to any target.

Blood Pact

Target player draws two cards and loses 2 life.

Expensive Taste

Exile the top two cards of target opponent's library face down. You may look at and play those cards for as long as they remain exiled.

Decadent Dragon

Flying, trample
Whenever Decadent Dragon attacks, create a Treasure token.

Decadent Dragon // Expensive Taste

Stonesplitter Bolt

Bargain (You may sacrifice an artifact, enchantment, or token as you cast this spell.)
Stonesplitter Bolt deals X damage to target creature or planeswalker. If this spell was bargained, it deals twice X damage to that permanent instead.

Spiteful Banditry

When Spiteful Banditry enters, it deals X damage to each creature.
Whenever one or more creatures your opponents control die, you create a Treasure token. This ability triggers only once each turn.

Defiler of Flesh

Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.

Myr Convert

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
{T}, Pay 2 life: Add one mana of any color.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent or discards a card.

Mithril Coat

Flash
Indestructible
When Mithril Coat enters, attach it to target legendary creature you control.
Equipped creature has indestructible.
Equip {3}

Lightning Bolt

Lightning Bolt deals 3 damage to any target.

Locthwain Scorn

Target creature gets -3/-3 until end of turn. You gain 2 life.

Virtue of Persistence

At the beginning of your upkeep, put target creature card from a graveyard onto the battlefield under your control.

Virtue of Persistence // Locthwain Scorn

Molten Collapse

Choose one. If you descended this turn, you may choose both instead. (You descended if a permanent card was put into your graveyard from anywhere.)
• Destroy target creature or planeswalker.
• Destroy target noncreature, nonland permanent with mana value 1 or less.

Ambition's Cost

You draw three cards and you lose 3 life.

Orcus, Prince of Undeath

Flying, trample
When Orcus, Prince of Undeath enters, choose one —
• Each other creature gets -X/-X until end of turn. You lose X life.
• Return up to X target creature cards with total mana value X or less from your graveyard to the battlefield. They gain haste until end of turn.

Rowan's Grim Search

Bargain (You may sacrifice an artifact, enchantment, or token as you cast this spell.)
If this spell was bargained, look at the top four cards of your library, then put up to two of them back on top of your library in any order and the rest into your graveyard.
You draw two cards and you lose 2 life.

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Doom Whisperer

Flying, trample
Pay 2 life: Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Abrade

Choose one —
• Abrade deals 3 damage to target creature.
• Destroy target artifact.

Banefire

Banefire deals X damage to any target.
If X is 5 or more, this spell can't be countered and the damage can't be prevented.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Electrodominance

Electrodominance deals X damage to any target. You may cast a spell with mana value X or less from your hand without paying its mana cost.

Shatterskull, the Hammer Pass

As Shatterskull, the Hammer Pass enters, you may pay 3 life. If you don't, it enters tapped.
{T}: Add {R}.

Shatterskull Smashing

Shatterskull Smashing deals X damage divided as you choose among up to two target creatures and/or planeswalkers. If X is 6 or more, Shatterskull Smashing deals twice X damage divided as you choose among them instead.

Shatterskull Smashing // Shatterskull, the Hammer Pass

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Tavern Swindler

{T}, Pay 3 life: Flip a coin. If you win the flip, you gain 6 life.

Bedevil

Destroy target artifact, creature, or planeswalker.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Rowan, Scion of War

Menace
{T}: Spells you cast this turn that are black and/or red cost {X} less to cast, where X is the amount of life you lost this turn. Activate only as a sorcery.

Bitter Triumph

As an additional cost to cast this spell, discard a card or pay 3 life.
Destroy target creature or planeswalker.

Dark Ritual

Font of Agonies

Whenever you pay life, put that many blood counters on Font of Agonies.
{1}{B}, Remove four blood counters from Font of Agonies: Destroy target creature.

Jaya's Immolating Inferno

(You may cast a legendary sorcery only if you control a legendary creature or planeswalker.)
Jaya's Immolating Inferno deals X damage to each of up to three targets.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Stormfist Crusader

Menace
At the beginning of your upkeep, each player draws a card and loses 1 life.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Crackle with Power

Crackle with Power deals five times X damage to each of up to X targets.

Defense Grid

Each spell costs {3} more to cast except during its controller's turn.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Big Score

As an additional cost to cast this spell, discard a card.
Draw two cards and create two Treasure tokens. (They're artifacts with "{T}, Sacrifice this artifact: Add one mana of any color.")

Dualcaster Mage

Flash
When Dualcaster Mage enters, copy target instant or sorcery spell. You may choose new targets for the copy.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Song of Totentanz

Create X 1/1 black Rat creature tokens with "This creature can't block." Creatures you control gain haste until end of turn.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Erebos's Intervention

Choose one —
• Target creature gets -X/-X until end of turn. You gain X life.
• Exile up to twice X target cards from graveyards.

March of Wretched Sorrow

As an additional cost to cast this spell, you may exile any number of black cards from your hand. This spell costs {2} less to cast for each card exiled this way.
March of Wretched Sorrow deals X damage to target creature or planeswalker and you gain X life.

Bolt Bend

This spell costs {3} less to cast if you control a creature with power 4 or greater.
Change the target of target spell or ability with a single target.