Descent into Madness

At the beginning of your upkeep, put a despair counter on this enchantment, then each player exiles X permanents they control and/or cards from their hand, where X is the number of despair counters on this enchantment.

Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Ophidian Eye

Flash (You may cast this spell any time you could cast an instant.)
Enchant creature
Whenever enchanted creature deals damage to an opponent, you may draw a card.

Circular Logic

Counter target spell unless its controller pays {1} for each card in your graveyard.
Madness {U} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Fiery Temper

Fiery Temper deals 3 damage to any target.
Madness {R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Call to the Netherworld

Return target black creature card from your graveyard to your hand.
Madness {0} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Malevolent Whispers

Gain control of target creature until end of turn. Untap that creature. It gets +2/+0 and gains haste until end of turn.
Madness {3}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Dark Withering

Destroy target nonblack creature.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Obsessive Search

Draw a card.
Madness {U} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Starlit Mantle

Flash (You may cast this spell any time you could cast an instant.)
Enchant creature you control
When this Aura enters, enchanted creature gains hexproof until end of turn. (It can't be the target of spells or abilities your opponents control.)
Enchanted creature gets +1/+1.

Mirror Shield

Equipped creature gets +0/+2 and has hexproof and "Whenever a creature with deathtouch blocks or becomes blocked by this creature, destroy that creature."
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Ring of Evos Isle

{2}: Equipped creature gains hexproof until end of turn. (It can't be the target of spells or abilities your opponents control.)
At the beginning of your upkeep, put a +1/+1 counter on equipped creature if it's blue.
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Winter Orb

As long as this artifact is untapped, players can't untap more than one land during their untap steps.

Mask of Avacyn

Equipped creature gets +1/+2 and has hexproof. (It can't be the target of spells or abilities your opponents control.)
Equip {3}

Just the Wind

Return target creature to its owner's hand.
Madness {U} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Mana Breach

Whenever a player casts a spell, that player returns a land they control to its owner's hand.

Nekusar, the Mindrazer

At the beginning of each player's draw step, that player draws an additional card.
Whenever an opponent draws a card, Nekusar deals 1 damage to that player.

Muck Drubb

Flash
When this creature enters, change the target of target spell that targets only a single creature to this creature.
Madness {2}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Psychotic Haze

Psychotic Haze deals 1 damage to each creature and each player.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Anje Falkenrath

Haste
{T}, Discard a card: Draw a card.
Whenever you discard a card, if it has madness, untap Anje Falkenrath.

Fevered Visions

At the beginning of each player's end step, that player draws a card. If the player is your opponent and has four or more cards in hand, this enchantment deals 2 damage to that player.

Alexi's Cloak

Flash
Enchant creature
Enchanted creature has shroud. (It can't be the target of spells or abilities.)

Grave Scrabbler

Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)
When this creature enters, if its madness cost was paid, you may return target creature card from a graveyard to its owner's hand.

Tandem Lookout

Soulbond (You may pair this creature with another unpaired creature when either enters. They remain paired for as long as you control both of them.)
As long as Tandem Lookout is paired with another creature, each of those creatures has "Whenever this creature deals damage to an opponent, draw a card."

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Murderous Compulsion

Destroy target tapped creature.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Curse of Fool's Wisdom

Enchant player
Whenever enchanted player draws a card, they lose 2 life and you gain 2 life.
Madness {3}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Curiosity

Enchant creature
Whenever enchanted creature deals damage to an opponent, you may draw a card.