Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Gatekeeper of Malakir

Kicker {B} (You may pay an additional {B} as you cast this spell.)
When Gatekeeper of Malakir enters the battlefield, if it was kicked, target player sacrifices a creature.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Soul Stair Expedition

Landfall — Whenever a land enters the battlefield under your control, you may put a quest counter on Soul Stair Expedition.
Remove three quest counters from Soul Stair Expedition and sacrifice it: Return up to two target creature cards from your graveyard to your hand.

Liturgy of Blood

Captivating Vampire

Other Vampire creatures you control get +1/+1.
Tap five untapped Vampires you control: Gain control of target creature. It becomes a Vampire in addition to its other types.

Liliana of the Dark Realms

+1: Search your library for a Swamp card, reveal it, put it into your hand, then shuffle.
−3: Target creature gets +X/+X or -X/-X until end of turn, where X is the number of Swamps you control.
−6: You get an emblem with "Swamps you control have '{T}: Add {B}{B}{B}{B}.'"

Blood Scrivener

If you would draw a card while you have no cards in hand, instead you draw two cards and you lose 1 life.

Predator's Gambit

Enchant creature
Enchanted creature gets +2/+1.
Enchanted creature has intimidate as long as its controller controls no other creatures. (It can't be blocked except by artifact creatures and/or creatures that share a color with it.)

Piranha Marsh

Piranha Marsh enters the battlefield tapped.
When Piranha Marsh enters the battlefield, target player loses 1 life.
{T}: Add {B}.

Vampire Outcasts

Bloodthirst 2 (If an opponent was dealt damage this turn, this creature enters the battlefield with two +1/+1 counters on it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Falkenrath Noble

Flying
Whenever Falkenrath Noble or another creature dies, target player loses 1 life and you gain 1 life.

Sorin's Thirst

Sorin's Thirst deals 2 damage to target creature and you gain 2 life.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Bloodthrone Vampire

Sacrifice a creature: Bloodthrone Vampire gets +2/+2 until end of turn.

Shadow Alley Denizen

Whenever another black creature enters the battlefield under your control, target creature gains intimidate until end of turn. (It can't be blocked except by artifact creatures and/or creatures that share a color with it.)

Butcher of Malakir

Flying
Whenever Butcher of Malakir or another creature you control dies, each opponent sacrifices a creature.

Profane Command

Choose two —
• Target player loses X life.
• Return target creature card with mana value X or less from your graveyard to the battlefield.
• Target creature gets -X/-X until end of turn.
• Up to X target creatures gain fear until end of turn. (They can't be blocked except by artifact creatures and/or black creatures.)

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Disciple of Bolas

When Disciple of Bolas enters the battlefield, sacrifice another creature. You gain X life and draw X cards, where X is that creature's power.

Ultimate Price

Reiver Demon

Flying
When Reiver Demon enters the battlefield, if you cast it from your hand, destroy all nonartifact, nonblack creatures. They can't be regenerated.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Lord of Lineage

Flying
Other Vampire creatures you control get +2/+2.
{T}: Create a 2/2 black Vampire creature token with flying.

Bloodline Keeper

Flying
{T}: Create a 2/2 black Vampire creature token with flying.
{B}: Transform Bloodline Keeper. Activate only if you control five or more Vampires.

Bloodline Keeper // Lord of Lineage

Skeletal Vampire

Flying
When Skeletal Vampire enters the battlefield, create two 1/1 black Bat creature tokens with flying.
{3}{B}{B}, Sacrifice a Bat: Create two 1/1 black Bat creature tokens with flying.
Sacrifice a Bat: Regenerate Skeletal Vampire.

Malakir Bloodwitch

Flying, protection from white
When Malakir Bloodwitch enters the battlefield, each opponent loses life equal to the number of Vampires you control. You gain life equal to the life lost this way.

Death's Approach

Enchant creature
Enchanted creature gets -X/-X, where X is the number of creature cards in its controller's graveyard.

Dirge of Dread

All creatures gain fear until end of turn. (They can't be blocked except by artifact creatures and/or black creatures.)
Cycling {1}{B} ({1}{B}, Discard this card: Draw a card.)
When you cycle Dirge of Dread, you may have target creature gain fear until end of turn.

Kalitas, Bloodchief of Ghet

{B}{B}{B}, {T}: Destroy target creature. If that creature dies this way, create a black Vampire creature token. Its power is equal to that creature's power and its toughness is equal to that creature's toughness.

Sorin's Vengeance

Sorin's Vengeance deals 10 damage to target player or planeswalker and you gain 10 life.

Guul Draz Vampire

As long as an opponent has 10 or less life, Guul Draz Vampire gets +2/+1 and has intimidate. (It can't be blocked except by artifact creatures and/or creatures that share a color with it.)

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Blood Seeker

Whenever a creature enters the battlefield under an opponent's control, you may have that player lose 1 life.

Grasp of Darkness

Target creature gets -4/-4 until end of turn.

Bloodlord of Vaasgoth

Bloodthirst 3 (If an opponent was dealt damage this turn, this creature enters the battlefield with three +1/+1 counters on it.)
Flying
Whenever you cast a Vampire creature spell, it gains bloodthirst 3.

Sorin Markov

+2: Sorin Markov deals 2 damage to any target and you gain 2 life.
−3: Target opponent's life total becomes 10.
−7: You control target player during that player's next turn.

Vampire Nighthawk

Blood Tribute

Kicker—Tap an untapped Vampire you control. (You may tap a Vampire you control in addition to any other costs as you cast this spell.)
Target opponent loses half their life, rounded up. If this spell was kicked, you gain life equal to the life lost this way.

Assassinate

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Urge to Feed

Target creature gets -3/-3 until end of turn. You may tap any number of untapped Vampire creatures you control. If you do, put a +1/+1 counter on each of those Vampires.

Vampire Hexmage

First strike
Sacrifice Vampire Hexmage: Remove all counters from target permanent.

Vampire's Bite

Kicker {2}{B} (You may pay an additional {2}{B} as you cast this spell.)
Target creature gets +3/+0 until end of turn. If this spell was kicked, that creature gains lifelink until end of turn. (Damage dealt by the creature also causes its controller to gain that much life.)

Dread Cacodemon

When Dread Cacodemon enters the battlefield, if you cast it from your hand, destroy all creatures your opponents control, then tap all other creatures you control.

Drana, Kalastria Bloodchief

Flying
{X}{B}{B}: Target creature gets -0/-X until end of turn and Drana, Kalastria Bloodchief gets +X/+0 until end of turn.

Enslave

Enchant creature
You control enchanted creature.
At the beginning of your upkeep, enchanted creature deals 1 damage to its owner.

Diabolic Revelation

Search your library for up to X cards, put those cards into your hand, then shuffle.

Chancellor of the Dross

You may reveal this card from your opening hand. If you do, at the beginning of the first upkeep, each opponent loses 3 life, then you gain life equal to the life lost this way.
Flying, lifelink

Coat of Arms

Each creature gets +1/+1 for each other creature on the battlefield that shares at least one creature type with it. (For example, if two Goblin Warriors and a Goblin Shaman are on the battlefield, each gets +2/+2.)

Halo Hunter

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
When Halo Hunter enters the battlefield, destroy target Angel.

Leyline of the Void

If Leyline of the Void is in your opening hand, you may begin the game with it on the battlefield.
If a card would be put into an opponent's graveyard from anywhere, exile it instead.

Black Sun's Zenith

Put X -1/-1 counters on each creature. Shuffle Black Sun's Zenith into its owner's library.

Doom Blade

Xathrid Gorgon

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
{2}{B}, {T}: Put a petrification counter on target creature. It gains defender and becomes a colorless artifact in addition to its other types. Its activated abilities can't be activated. (A creature with defender can't attack.)

Triumph of Cruelty

At the beginning of your upkeep, target opponent discards a card if you control the creature with the greatest power or tied for the greatest power.

Geth's Verdict

Target player sacrifices a creature and loses 1 life.

Essence Harvest

Target player loses X life and you gain X life, where X is the greatest power among creatures you control.

Vampire Nocturnus

Play with the top card of your library revealed.
As long as the top card of your library is black, Vampire Nocturnus and other Vampire creatures you control get +2/+1 and have flying.

Nightmare

At the beginning of combat on your turn, if a card was put into exile this turn, put a +1/+1 counter on this creature.

Ancient Craving

You draw three cards and you lose 3 life.

Feast of Blood

Cast this spell only if you control two or more Vampires.
Destroy target creature. You gain 4 life.

Duskmantle Prowler

Haste (This creature can attack and {T} as soon as it comes under your control.)
Exalted (Whenever a creature you control attacks alone, that creature gets +1/+1 until end of turn.)

Royal Assassin

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Consume Spirit

Spend only black mana on X.
Consume Spirit deals X damage to any target and you gain X life.