Ulamog, the Ceaseless Hunger

When you cast this spell, exile two target permanents.
Indestructible
Whenever Ulamog, the Ceaseless Hunger attacks, defending player exiles the top twenty cards of their library.

Ancient Stirrings

Look at the top five cards of your library. You may reveal a colorless card from among them and put it into your hand. Then put the rest on the bottom of your library in any order.

Sundering Titan

When Sundering Titan enters or leaves the battlefield, choose a land of each basic land type, then destroy those lands.

Karn, the Great Creator

Activated abilities of artifacts your opponents control can't be activated.
+1: Until your next turn, up to one target noncreature artifact becomes an artifact creature with power and toughness each equal to its mana value.
−2: You may reveal an artifact card you own from outside the game or choose a face-up artifact card you own in exile. Put that card into your hand.

Liquimetal Coating

{T}: Target permanent becomes an artifact in addition to its other types until end of turn.

Forest

Haywire Mite

When Haywire Mite dies, you gain 2 life.
{G}, Sacrifice Haywire Mite: Exile target noncreature artifact or noncreature enchantment.

Phyrexian Metamorph

({U/P} can be paid with either {U} or 2 life.)
You may have Phyrexian Metamorph enter as a copy of any artifact or creature on the battlefield, except it's an artifact in addition to its other types.

Oblivion Stone

{4}, {T}: Put a fate counter on target permanent.
{5}, {T}, Sacrifice Oblivion Stone: Destroy each nonland permanent without a fate counter on it, then remove all fate counters from all permanents.

Wurmcoil Engine

Deathtouch, lifelink
When Wurmcoil Engine dies, create a 3/3 colorless Phyrexian Wurm artifact creature token with deathtouch and a 3/3 colorless Phyrexian Wurm artifact creature token with lifelink.

The Stone Brain

{2}, {T}, Exile The Stone Brain: Choose a card name. Search target opponent's graveyard, hand, and library for up to four cards with that name and exile them. That player shuffles, then draws a card for each card exiled from their hand this way. Activate only as a sorcery.

Emrakul, the Promised End

This spell costs {1} less to cast for each card type among cards in your graveyard.
When you cast this spell, you gain control of target opponent during that player's next turn. After that turn, that player takes an extra turn.
Flying, trample, protection from instants

Urza's Mine

{T}: Add {C}. If you control an Urza's Power-Plant and an Urza's Tower, add {C}{C} instead.

Cityscape Leveler

Trample
When you cast this spell and whenever Cityscape Leveler attacks, destroy up to one target nonland permanent. Its controller creates a tapped Powerstone token.
Unearth {8}

All Is Dust

Each player sacrifices all permanents they control that are one or more colors.

Boseiju, Who Endures

{T}: Add {G}.
Channel — {1}{G}, Discard Boseiju, Who Endures: Destroy target artifact, enchantment, or nonbasic land an opponent controls. That player may search their library for a land card with a basic land type, put it onto the battlefield, then shuffle. This ability costs {1} less to activate for each legendary creature you control.

Chromatic Sphere

{1}, {T}, Sacrifice Chromatic Sphere: Add one mana of any color. Draw a card.

Sylvan Scrying

Search your library for a land card, reveal it, put it into your hand, then shuffle.

Walking Ballista

Walking Ballista enters with X +1/+1 counters on it.
{4}: Put a +1/+1 counter on Walking Ballista.
Remove a +1/+1 counter from Walking Ballista: It deals 1 damage to any target.

Urza's Power Plant

{T}: Add {C}. If you control an Urza's Mine and an Urza's Tower, add {C}{C} instead.

Talisman of Resilience

{T}: Add {C}.
{T}: Add {B} or {G}. Talisman of Resilience deals 1 damage to you.

Dismember

({B/P} can be paid with either {B} or 2 life.)
Target creature gets -5/-5 until end of turn.

Ugin, the Spirit Dragon

+2: Ugin, the Spirit Dragon deals 3 damage to any target.
−X: Exile each permanent with mana value X or less that's one or more colors.
−10: You gain 7 life, draw seven cards, then put up to seven permanent cards from your hand onto the battlefield.

The One Ring

Indestructible
When The One Ring enters, if you cast it, you gain protection from everything until your next turn.
At the beginning of your upkeep, you lose 1 life for each burden counter on The One Ring.
{T}: Put a burden counter on The One Ring, then draw a card for each burden counter on The One Ring.

Urza's Tower

{T}: Add {C}. If you control an Urza's Mine and an Urza's Power-Plant, add {C}{C}{C} instead.

Chalice of the Void

Chalice of the Void enters with X charge counters on it.
Whenever a player casts a spell with mana value equal to the number of charge counters on Chalice of the Void, counter that spell.

Stone of Erech

If a creature an opponent controls would die, exile it instead.
{2}, {T}, Sacrifice Stone of Erech: Exile target player's graveyard. Draw a card.

Urza's Saga

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Urza's Saga gains "{T}: Add {C}."
II — Urza's Saga gains "{2}, {T}: Create a 0/0 colorless Construct artifact creature token with 'This creature gets +1/+1 for each artifact you control.'"
III — Search your library for an artifact card with mana cost {0} or {1}, put it onto the battlefield, then shuffle.

Expedition Map

{2}, {T}, Sacrifice this artifact: Search your library for a land card, reveal it, put it into your hand, then shuffle.

Tormod's Crypt

{T}, Sacrifice Tormod's Crypt: Exile target player's graveyard.

Pithing Needle

As Pithing Needle enters, choose a card name.
Activated abilities of sources with the chosen name can't be activated unless they're mana abilities.

Engineered Explosives

Sunburst (This enters with a charge counter on it for each color of mana spent to cast it.)
{2}, Sacrifice Engineered Explosives: Destroy each nonland permanent with mana value equal to the number of charge counters on Engineered Explosives.